4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Maʻemaʻe >98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory

ʻO ka wehewehe pōkole:

Inoa: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

CAS: 417721-36-9

Maʻemaʻe: >98.5% (HPLC)

ʻAno: Keʻokeʻo-keʻokeʻo a i ka pauda Melemele Māmā

Kūwaena o Lenvatinib Mesylate CAS 857890-39-2

ʻO ke kūlana kiʻekiʻe, ka hana kālepa

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Me ka Maʻemaʻe Kiʻekiʻe
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Na Waiwai Kemika:

Inoa Kimia	4-Chloro-7-Methoxyquinoline-6-Carboxamide
Nā huaʻōlelo like	4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Lenvatinib haumia 12;Lenvatinib haumia B;Lenvatinib haumia LFS-B
Helu CAS	417721-36-9
Helu CAT	RF-PI1971
Kūlana Kūʻai	Ma ka waihona, ka mana hana 50MT/makahiki
ʻĀpana Molekala	C11H9ClN2O2
Kaumaha Molecular	236.65
Lae hehee	>205℃ (Dek.)
ʻO ka mānoanoa	1.380±0.060 g/cm3
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Pau-keʻokeʻo a i ka pauda Melemele Māmā
Maʻemaʻe / Kaʻina Hanana	>98.5% (HPLC)
Nalo ma ka maloo	<0.50%
Koena ma ka Ignition	<0.50%
Huina paumaele	<1.50%
Proton NMR Spectrum	Kūlike i ka hoʻolālā
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	Waena o Lenvatinib Mesylate (CAS: 857890-39-2)

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

Hoʻohana nui ʻia ʻo 4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) ma ke ʻano he waena o Lenvatinib Mesylate (CAS: 857890-39-2).Hoʻomohala ʻia e Eisai Inc., ʻo lenvatinib mesylate he mea hoʻokae endothelial growth factor receptor (VEGF) i loaʻa ka hana e kūʻē i nā subtypes VEGF 1, 2, a me 3 a ua ʻae ʻia e ka FDA ma 2015 no ka mālama ʻana i ka maʻi maʻi thyroid like ʻole. hou, metastatic, a holomua paha a ʻaʻole i pane i ka lāʻau iodine radioactive.I Mei 2016, ua ʻae ka FDA i ka lāʻau lapaʻau ma ke ʻano he hui hui me everolimus no ka mālama ʻana i ka maʻi maʻi maʻi renal cell carcinoma.No ka mea, ua manaʻo ʻia ʻo VEGF (a me ka fibroblast growth factor receptors, i kapa ʻia ʻo FGFRs) i ke kuleana i nā ala hōʻailona cardiovascular, ua manaʻo ʻia ʻo VEGF2R a me FGFR inhibition nā mea hana ma hope o ka hopena mua o ka lenvatinib mesylate, ʻo ia ka hypertension.