5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde CAS 881674-56-2 Vonoprazan Fumarate Ma'ema'e Waena ≥99.0%
Hoʻolako ʻia ʻo Vonoprazan Fumarate a me Intermediate pili
5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde CAS 881674-56-2
Pyridine-3-Sulfonyl Chloride CAS 16133-25-8
Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Inoa Kimia | 5-(2-Fluorophenyl)-1H-Pyrrole-3-Carbaldehyde |
| Nā huaʻōlelo like | Vonoprazan Fumarate (TAK-438) Waena 3 |
| Helu CAS | 881674-56-2 |
| Helu CAT | RF-PI330 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C11H8FNO |
| Kaumaha Molecular | 189.19 |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Melemele a Palaunu Pada |
| Lae hehee | 122.0~131.0 ℃ |
| ʻIkepili: RT(HPLC) | E kulike me ka maʻamau kuhikuhi |
| Nalo ma ka maloo ana | ≤0.50% |
| Koena Ma ka Ignition | ≤0.50% |
| Na mea pili | |
| Maemae | ≥99.0% |
| ʻO kēlā me kēia haumia hoʻokahi | ≤0.50% |
| Huina paumaele | ≤1.0% |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Ka waena o Vonoprazan Fumarate (TAK-438) (CAS 881681-01-2) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
5-(2-Fluorophenyl) -1H-Pyrrole-3-Carbaldehyde (CAS 881674-56-2) hana ma ke ʻano he reagent i ka hoʻomākaukau synthetic o nā derivatives pyrrole novel e like me ka pāpaʻi pākīpika-competitive acid blocker (P-CAB).ʻO 5-(2-Fluorophenyl)pyrrole-3-Carboxaldehyde ka waena o Vonoprazan Fumarate (CAS 1260141-27-2).ʻO Vonoprazan fumarate (Takecab®), iʻikeʻia a hoʻomohalaʻia e Takeda a me Otsuka, ua'āponoʻia e ka PMDA o Iapana i ka lāʻo Dekemaba 2014, a ua hōʻikeʻia no ka mālamaʻana i ka maʻi'ōpū, ka maʻi maʻi duodenal a me ka reflux esophagitis.Loaʻa i ka Vonoprazan fumarate kahi hana hou o ka hana i kapa ʻia ʻo potassium-competitive acid blockers, e hoʻokūkū hoʻokūkū i ka hoʻopaʻa ʻana o nā ion potassium iā H+, K+-ATPase (ʻike pū ʻia ʻo ka pauma proton) i ka hana hope loa o ka huna ʻana o ka ʻōpū o ka ʻōpū i loko o nā pūnaʻi parietal ʻōpū.ʻAʻole ʻae ʻo Vonoprazan i ka hana Na +, K + -ATPase a hiki i ka 500 mau manawa kiʻekiʻe ma mua o kā lākou mau waiwai IC50 e kūʻē i ka hana gastric H +, K + -ATPase.Eia kekahi, ʻaʻole i hoʻopilikia ʻia ka lāʻau lapaʻau e ka ʻōpū huna huna, ʻaʻole like me nā PPI.
