5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 ʻOihana Kūwaena ʻo Dapagliflozin
Mea Manufacturer Supply, High Purity, Commercial Production
Dapagliflozin (CAS: 461432-26-8) Nā Kūwaena Pili:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Inoa Kimia | 5-Bromo-2-Chlorobenzoic Acid |
| Nā huaʻōlelo like | 2-Chloro-5-Bromobenzoic Acid |
| Helu CAS | 21739-92-4 |
| Helu CAT | RF-PI439 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C7H4BrClO2 |
| Kaumaha Molecular | 235.46 |
| Lae hehee | 154.0 a i 156.0 ℃ (māmā) |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Pau-keʻokeʻo a i ka pauda Melemele Māmā |
| Hoʻāʻo | ≥99.0% |
| Wai (KF) | ≤0.50% |
| Koena ma ka Ignition | ≤0.30% |
| 2-Chlorobenzoic Acid | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Huina paumaele | ≤1.0% |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Ka waena o Dapagliflozin (CAS: 461432-26-8), ʻano maʻi diabetes II |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
Hoʻohana ʻia ka 5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) ma ke ʻano he mea hoʻomaka i ka synthesis o Dapagliflozin (CAS: 461432-26-8), kahi mea koho sodium-glucose cotransporter-2 inhibitor e hōʻemi i ka renal. glucose reabsorption a hoʻohana ʻia e mālama i nā maʻi me ka maʻi diabetes type II.ʻO Dapagliflozin kahi mea pale SGLT-2 (SLC5A2) ikaika a koho me EC50 o 1.1 nM.Loaʻa iā ia ka permeability maikaʻi ma waena o nā membrane cell Caco-2 a he substrate no ka P-glycoprotein (P-gp).Ua ʻae ʻia ʻo Dapagliflozin i ka makahiki 2012 e FDA.
