5-Bromo-2-Chloropyrimidine CAS 32779-36-5 Maʻemaʻe ≥99.5% (HPLC) Macitentan Intermediate Factory
Mea Manufacturer Hoolako Kalepa Macitentan Related Intermediates
5-(4-Bromophenyl)-4,6-Dichloropyrimidine CAS 146533-41-7
5-Bromo-2-Chloropyrimidine CAS 32779-36-5
| Inoa Kimia | 5-Bromo-2-Chloropyrimidine |
| Nā huaʻōlelo like | 2-Chloro-5-Bromopyrimidine;ʻO Macitentan Intermediate 5 |
| Helu CAS | 32779-36-5 |
| Helu CAT | RF-PI854 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C4H2BrClN2 |
| Kaumaha Molecular | 193.43 |
| Lae hehee | 73.0~79.0℃ (māmā) |
| Lae paila | 95 ℃/15 mmHg |
| Ka hoʻoheheʻe | Hiki ke hoʻoheheʻe ʻia i ka Methanol;ʻAʻole hiki ke hoʻonā i ka wai |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
| ʻIkepili | IR/HPLC |
| Maʻemaʻe / Kaʻina Hanana | ≥99.5% (HPLC) |
| Māmā (KF) | ≤0.50% |
| Koena ma ka Ignition | ≤0.20% |
| Hoʻokahi haumia | ≤0.30% |
| Huina paumaele | ≤0.50% |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | Nā Kūwaena Lapaʻau;Macitentan Intermediate |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
Hoʻohana ʻia ʻo 5-Bromo-2-Chloropyrimidine (CAS: 32779-36-5) ma ke ʻano he pharmaceutical intermediate, i ka synthesis o Active Pharmaceutical Ingredients (APIs).Hoʻohana ʻia nō hoʻi ia i loko o ka hoʻohui ʻana i ke keʻa o nā organometallics indium me 2,5-Dihalopyrimidines.ʻO 5-Bromo-2-Chloropyrimidine ka mea waena o Macitentan (CAS: 441798-33-0).Ua loaʻa iā Macitentan ka ʻae ʻana o ka US FDA ma ʻOkakopa 2013 no ka mālama ʻana i ka pulmonary arterial hypertension (PAH) (WHO group I) e hoʻopaneʻe i ka piʻi ʻana o ka maʻi.
