6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile CAS 356783-31-8 Maʻemaʻe ≥98.0% (HPLC) Favipiravir Intermediate COVID-19
Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Hāʻawi Kalepa Favipiravir a me nā mea pili e pili ana:
Favipiravir CAS 259793-96-9
2-Aminopropanediamide CAS 62009-47-6
Diethyl Aminomalonate Hydrochloride CAS 13433-00-6
3,6-Dichloropyrazine-2-Carbonitrile CAS 356783-16-9
3,6-Difluoropyrazine-2-Carbonitrile CAS 356783-28-3
6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile CAS 356783-31-8
6-Bromo-3-Hydroxypyrazine-2-Carboxamide CAS 259793-88-9
3-Hydroxypyrazine-2-Carboxamide CAS 55321-99-8
Inoa Kimia | 6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile |
Nā huaʻōlelo like | 6-Fluoro-3-oxo-3,4-Dihydropyrazine-2-Carbonitrile |
Helu CAS | 356783-31-8 |
Helu CAT | RF-API294 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C5H2FN3O |
Kaumaha Molecular | 139.09 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Melemele ʻeleʻele a hiki i ka pauda keʻokeʻo |
ʻIkepili | IR, HPLC |
Māmā (KF) | ≤1.0% |
Koena ma ka Ignition | ≤0.50% |
Hoʻokahi haumia | ≤1.0% |
Huina paumaele | ≤2.0% |
Nā Metala Kaumaha | ≤20ppm |
Maemae | ≥98.0% (na HPLC) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena o Favipiravir (CAS 259793-96-9);Antiviral;COVID-19 |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO 6-Fluoro-3-Hydroxypyrazine-2-Carbonitrile (CAS 356783-31-8) he mea waena o Favipiravir (CAS 259793-96-9).ʻO Favipiravir kahi lāʻau antiviral ākea ākea hou e kuhikuhi ana i ka RNA-dependent RNA polymerase (RdRp).Ua hoʻokumu mua ʻia ʻo Favipiravir i ka hopena o 1990s e kahi hui i kūʻai ʻia ma hope e ka ʻoihana Iapana ʻo Fujifilm ma ke ʻano o kāna hoʻololi ʻana mai ka ʻoihana kiʻi i ka mālama olakino.Ma hope o ka hoʻāʻo ʻia ʻana e kūʻē i ka nui o nā maʻi maʻi, ua ʻae ʻia ka lāʻau lapaʻau ma Iapana i ka makahiki 2014 no ka hoʻohana pilikia ʻana i nā maʻi maʻi maʻi a i ʻole e mālama i nā maʻi maʻi hou.I ka wā o ka puka ʻana o ka coronavirus hou, ua hōʻike ʻia nā hopena o ka Phase I clinical study o ka lāʻau lapaʻau i paʻi ʻia ma Malaki 2020 e loaʻa paha i ka lāʻau lapaʻau ka hopena o ka wikiwiki ʻana i ka maʻi maʻi e hōʻoluʻolu i ka holomua o ka pneumonia coronavirus hou.Hiki ke hoʻohana ʻia ʻo Favipiravir i ka mālama ʻana i nā maʻi me COVID-19 i ʻōlelo ʻia e WHO.Ua hoʻomaʻemaʻe ʻia e ka Drugs Controller General of India (DCGI) no ka hoʻohana ʻana i ka "emergency restricted" ma waena o nā mea maʻi COVID-19.