6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9 PF-07321332 Boceprevir Intermediate
Mea Kūʻai Kūʻai PF-07321332 Paxlovid E pili ana i waena me ke kūlana kiʻekiʻe.
L-tert-Leucine (H-Tle-OH) CAS 20859-02-3
Caronic Anhydride CAS 67911-21-1
(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-Carboxylic Acid Methyl Ester Hydrochloride 565456-77-1
Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate CAS 328086-60-8
6,6-Dimethyl-3-azabicyclo[3.1.0]hexane CAS 943516-54-9
Inoa Kimia | 6,6-Dimethyl-3-azabicyclo[3.1.0]hexane |
Helu CAS | 943516-54-9 |
Helu CAT | RF-PI316 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C7H13N |
Kaumaha Molecular | 111.18 |
Lae paila | 135 ℃ |
ʻO ka mānoanoa | 0.911 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | ʻO ka wai alohilohi kala ʻole |
Maemae | ≥98.0% |
Hoʻokahi haumia | ≤0.50% |
Huina paumaele | ≤2.0% |
Nā Metala Kaumaha | ≤20ppm |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena o PF-07321332 Paxlovid (CAS 2628280-40-8) a me Boceprevir (CAS 394730-60-0) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO 6,6-Dimethyl-3-azabicyclo [3.1.0] hexane (CAS 943516-54-9) ka waena o PF-07321332 Paxlovid (CAS 2628280-40-8) a me Boceprevir (CAS 394730-60-0).ʻO ka Pfizer's Paxlovid PF-07321332 kahi lāʻau lapaʻau antiviral waha e kuhikuhi ana i ka SARS-CoV-2 betacoronavirus e pale i ka COVID-19.ʻO Paxlovid kahi mea pale protease i hōʻike i ka hana antiviral in vitro e kūʻē iā SARS-CoV-2 a me nā coronaviruses ʻē aʻe, e hōʻike ana i ka hiki ke hoʻohana i ka mālama ʻana i ka COVID-19, a me ka hoʻohana ʻana i nā hoʻoweliweli virus e hiki mai ana, wahi a Pfizer.ʻO ka Boceprevir (EBP 520) he mea hoʻopaneʻe protease HCV NS3 me ka Ki o 14 nM i loko o nā hoʻokolohua enzyme ʻelua a me kahi EC90 o 350 nM i ka hoʻopiʻi replicon cell-based.Kāohi ʻo Boceprevir i ka hana SARS-CoV-2 3CLpro.