7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3 Tolvaptan Intermediate
Mea Hana Mea Hana, High Quality, Commercial Production
Tolvaptan a me nā mea pili e pili ana:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
Inoa Kimia | 7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-one |
Nā huaʻōlelo like | 7-Chloro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-one;7-Chloro-3,4-dihydro-1H-benzo[b]azepin-5(2H)-kahi |
Helu CAS | 160129-45-3 |
Helu CAT | RF-PI395 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
ʻĀpana Molekala | C10H10ClNO |
Kaumaha Molecular | 195.65 |
Lae hehee | 103.0 a 107.0 ℃ |
Ka hoʻoheheʻe | Hiki ke hoʻoheheʻe ʻia i ka Methanol |
Brand | ʻO Ruifu Chemical |
'ikamu | Nā kikoʻī |
Ka nana aku | ʻOmaomao māmā a i ka pauda melemele māmā |
Nā ʻano ʻike | NMR, HPLC |
Maʻemaʻe / Kaʻina Hanana | ≥99.0% (HPLC) |
Nalo ma ka maloo | ≤1.0% |
Koena ma ka Ignition | ≤0.50% |
ʻO kēlā me kēia haumia hoʻokahi | ≤0.50% |
Huina paumaele | ≤1.0% |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Intermediate o Tolvaptan (CAS 150683-30-0), ka mālama ʻana i ka Hyponatremia |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
ʻO 7-Chloro-1,2,3,4-tetrahydrobenzo [b] azepin-5-one (CAS 160129-45-3) he mea waena i ka synthesis o Tolvaptan (CAS 150683-30-0).ʻO Tolvaptan kahi mea koho, hoʻokūkū waha nonpeptide arginine vasopressin V2 receptor antagonist me kahi IC50 o 1.28µM no ka pale ʻana i ka AVP-induced platelet aggregation.Hoʻohana ʻia ʻo Tolvaptan e mālama i ka hyponatremia e pili ana me ka puʻuwai congestive, cirrhosis, a me ka maʻi o ka hormone antidiuretic kūpono ʻole.Aia ʻo Tolvaptan i nā hoʻokolohua lapaʻau wikiwiki no ka maʻi maʻi maʻi polycystic.ʻO ka lapaʻau ʻana me Tolvaptan e hoʻemi wikiwiki a hoʻomau i ke kaumaha o ke kino e like me ka piʻi ʻana o ka mimi, hoʻomaikaʻi a / a hoʻomaʻamaʻa paha i ka sodium serum i nā maʻi hyponatremic, e hōʻemi i nā hōʻailona a me nā hōʻailona o ka congestion a hoʻonui i ka makewai.