7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2 Maʻemaʻe >99.0% (HPLC) Afatinib Dimaleate Intermediate Factory

ʻO ka wehewehe pōkole:

Inoa: 7-Chloro-6-Nitro-4-Hydroxyquinazoline

CAS: 53449-14-2

Maʻemaʻe: >99.0% (HPLC)

ʻAno: Melemele māmā a hiki i ka pauda ʻulaʻula

Waena o Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Nā Kūwaena Hoʻolako Kimia o Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4(1H)-hoʻokahi CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5

Na Waiwai Kemika:

Inoa Kimia	7-Chloro-6-Nitro-4-Hydroxyquinazoline
Nā huaʻōlelo like	7-Chloro-4-Hydroxy-6-Nitroquinazoline;7-Chloro-6-Nitro-4-Quinazolinol;7-Chloro-6-Nitro-4-Quinazolinone;7-Chloro-6-Nitro-4(3H)-Quinazolinone;7-Chloro-6-Nitro-3,4-Dihydroquinazolin-4-one;7-Chloro-6-Nitroquinazolin-4(3H)-hoʻokahi
Helu CAS	53449-14-2
Helu CAT	RF-PI2030
Kūlana Kūʻai	Ma ka waihona, hoʻonui ʻia a hiki i nā tona
ʻĀpana Molekala	C8H4ClN3O3
Kaumaha Molecular	225.59
ʻO ka ʻike	Paʻa wela
Ka hikiwawe	Hiki ke hoʻoheheʻe ʻia i ka Dimethylformamide
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Melemele māmā i ka pauda ʻulaʻula
ʻIkepili (HPLC)	Pono ka manawa paʻa o ka laʻana me ka maʻamau
Maʻemaʻe / Kaʻina Hanana	>99.0% (HPLC)
Lae hehee	300.0~303.0 ℃
Waiwai (KF)	<0.50%
Koena ma ka Ignition	<0.30%
haumia 1	<0.50% (7-Chloro-4-Hydroxyquinazoline CAS: 31374-18-2)
haumia 2	<0.50% (5,7-Dichloro-4[1H]quinazolinone)
haumia 3	<1.00% (7-Chloro-8-Nitro-4[1H]quinazolinone)
ʻO nā mea haumia hoʻokahi	<0.20%
Huina paumaele	<1.00%
Nā Metala Kaumaha (e like me Pb)	<20ppm
Infrared Spectrum	Kūlike i ka hoʻolālā
Proton NMR Spectrum	Proton NMR Spectrum
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	Ka waena o Afatinib, Afatinib Dimaleate

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

ʻO 7-Chloro-6-Nitro-4-Hydroxyquinazoline (CAS: 53449-14-2) kahi mea waena o Afatinib Dimaleate (CAS: 850140-73-7).He ʻohana ErbB hiki ʻole ke hoʻohuli ʻia ʻo Afatinib e kāohi i ka hoʻouna ʻana i ka ʻike a pale i nā ala nui e pili ana i ka ulu ʻana o ka maʻi kanesa a me ka mahele.No ka mea hiki ke hoʻoulu ʻia ka mīkini unuhi ʻike ʻohana ErbB e nā homodimers a me nā heterodimers, hiki ke hoʻopau i ka lawe ʻana i ka ʻike ma lalo o ka ʻohana ErbB (e like me EGFR, HER2, ErbB3 a me ErbB4).Hoʻohana ʻia ʻo Afatinib no ka mālama ʻana i kekahi ʻano o ka maʻi maʻi ʻaʻai māmā (non-small cell lung cancer) i laha i nā wahi ʻē aʻe o ke kino.Aia ia i kahi papa o nā lāʻau i ʻike ʻia he kinase inhibitors.Hana ia ma ka hoʻolohi a hoʻōki paha i ka ulu ʻana o nā maʻi maʻi maʻi.Hoʻopili ia i kekahi pūmua (epidermal receptor-EGFR) i kekahi mau maʻi koko.