7-Ethyl-10-Hydroxycamptothecin CAS 86639-52-3 Irinotecan Hydrochloride Waena Ma'ema'e Ki'eki'e
Mea Hana Hana Irinotecan a me nā mea pili i waena:
Irinotecan Hydrochloride CAS: 100286-90-6
Irinotecan Free Base CAS: 97682-44-5
Irinotecan Hydrochloride Trihydrate CAS: 136572-09-3
7-Ethyl-10-Hydroxycamptothecin CAS: 86639-52-3
1-Chlorocarbonyl-4-Piperidinopiperidine Hydrochloride CAS: 143254-82-4
| Inoa Kimia | 7-Ethyl-10-Hydroxycamptothecin |
| Nā huaʻōlelo like | SN-38 |
| Helu CAS | 86639-52-3 |
| Helu CAT | RF-PI242 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
| ʻĀpana Molekala | C22H20N2O5 |
| Kaumaha Molecular | 392.41 |
| Brand | ʻO Ruifu Chemical |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Māmā Melemele Keʻokeʻo Puka |
| ʻIkepili (IR, UV) | (1) E like me nā koi (2) E hoʻokō me nā hoʻokolohua ʻae ʻia e like me ka spectrum maʻamau kuhikuhi. |
| Lae hehee | 228.0~235.0 ℃ |
| Na mea pili | ≤1.5% |
| 10-Hydroxycamptothecin | ≤0.30% |
| 7-Cthylcamptothecin | ≤0.70% |
| ʻO ka haumia ʻike ʻole ʻia | ≤0.50% |
| Nalo ma ka maloo | ≤1.0% |
| Metala Kaumaha | ≤10ppm |
| Koena ma ka Ignition | ≤0.10% |
| Akaka o ka Haʻina | Akaka |
| Hoʻāʻo | ≥98.0% (HPLC) |
| Kūlana hoʻāʻo | ʻOihana Kūlana |
| Hoʻohana | ʻO ka lāʻau lapaʻau waena o Irinotecan |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) me ke kūlana kiʻekiʻe.ʻO 7-Ethyl-10-Hydroxycamptothecin (CAS: 86639-52-3) he metabolite ikaika o ka Topoisomerase I inhibitor Irinotecan.SN-38 (NK012) kaohi i ka DNA a me RNA synthesis me IC50s o 0.077 a me 1.3 μM.ʻO 7-Ethyl-10-Hydroxycamptothecin (SN-38), ʻo ia ka metabolite ikaika o Irinotecan, he semisynthetic derivative o camptothecin, he alkaloid quinoline-based i loaʻa i ka ʻili o ka lāʻau camptotheca Kina a me ka lāʻau nothapodytes ʻĀsia.ʻOiai ʻo 7-Ethyl-10-Hydroxycamptothecin a hiki i ka 1,000 mau manawa ʻoi aku ka ikaika ma mua o Irinotecan, ʻaʻole ia i hoʻololi ʻia i moho lāʻau kūpono no ka mea hiki ʻole ke hoʻoheheʻe.Ke hoʻokau ʻia nei ia i nā hoʻokolohua lapaʻau i hui pū ʻia me nā ʻāpana ʻē aʻe i hiki ke ʻae ʻia i ka hopena e like me ka lāʻau antineoplastic.
