7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1 Maʻemaʻe >99.0% (GC) Agomelatine Intermediate
Mea alakaʻi alakaʻi a me ka mea hoʻolako o Agomelatine Intermediates
Agomelatine CAS 138112-76-2
7-Methoxy-1-Tetralone CAS 6836-19-7
7-Methoxy-1-Naphthaleneacetic Acid CAS 6836-22-2
7-Methoxy-1-Naphthylacetonitrile CAS 138113-08-3
7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester CAS 6836-21-1
Please contact: alvin@ruifuchem.com
| Inoa Kimia | 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester |
| Nā huaʻōlelo like | Ethyl 2-(7-Methoxynaphthalen-1-yl)acetate |
| Helu CAS | 6836-21-1 |
| Helu CAT | RF2687 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C15H16O3 |
| Kaumaha Molecular | 244.29 |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Māmā Melemele Alohilohi Liquid |
| Maʻemaʻe / Kaʻina Hanana | >99.0% (GC) |
| Wai (na Karl Fischer) | <0.50% |
| Na mea pili | <1.00% |
| Infrared Spectrum | Kūlike i ka hoʻolālā |
| NMR Spectrum | Kūlike i ka hoʻolālā |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | Lapaʻau Kūwaena o Agomelatine (CAS: 138112-76-2) |
Pūʻolo: Fluorinated ʻO ka'ōmole, 25kg / Barrel, aiʻole e like me ka makemake o ka mea kūʻai
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
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ʻO ka 7-Methoxy-1-Naphthaleneacetic Acid Ethyl Ester (CAS: 6836-21-1) he mea hoʻohana pono i ka organik synthetic intermediate, hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau waena o Agomelatine (CAS: 138112-76-2).ʻO Agomelatine, ka mea i hoʻomohala ʻia e ka hui French Servier, ʻo ia ka honua melatonin receptors MT1 a me MT2 agonist class of antidepressants.Hoʻohana ia i ka mālama ʻana i nā poʻe maʻi makua me ke kaumaha koʻikoʻi.ʻO Agomelatine kahi lāʻau antidepressant.ʻO Agomelatine kahi agonist o ka melatonin (MT) receptors a me kahi derivative o melatonin.Hoʻopili ia i nā mea loaʻa MT1 a me MT2 (Kis = 0.14 a me 0.41 nM, kēlā me kēia) a loaʻa kahi waiwai EC50 o 0.1 nM i kahi [35S] GTPγS hoʻopaʻa ʻana i ka hoʻohana ʻana i nā cell CHO e hōʻike ana i nā mea loaʻa MT2.Hoʻokaʻawale ʻia ʻo ia ma ke ʻano he norepinephrine-dopamine disinhibitor (NDDI) ma muli o kāna antagonism o ka 5-HT2C receptor.ʻO ka hoʻouluʻana o nā mea loaʻa 5-HT2C e ke serotonin e kāohi i ka hoʻokuʻu dopamine a me nā norepinephrine.
