S-Adenosyl-L-Methionine (Ademetionine; SAMe) CAS 29908-03-0
ʻO Ruifu Chemical ka mea hana nui o S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) me ke kūlana kiʻekiʻe.Hiki iā Ruifu Chemical ke hāʻawi aku i ka honua holoʻokoʻa, ke kumukūʻai hoʻokūkū, ka lawelawe maikaʻi loa, ka liʻiliʻi a me ka nui nui i loaʻa.Kūʻai iā S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com
Inoa Kimia | S-Adenosyl-L-Methionine |
Nā huaʻōlelo like | Ademetionine;S-Adenosylmethionine;SAME;SAM;AdoMet |
Kūlana Kūʻai | Ma ke Kahua, Hana Hana Kūʻai |
Helu CAS | 29908-03-0 |
ʻĀpana Molekala | C15H22N6O5S |
Kaumaha Molecular | 398.44 g/mol |
Lae hehee | 267.0~269.0 ℃ |
Pilikino | Hygroscopic loa |
Hiki i ka wai | Hiki i ka wai |
Aala & ʻono | Nā hiʻohiʻona |
COA & MSDS | Loaʻa |
Laʻana | Loaʻa |
Ke kumu | Shanghai, Kina |
Brand | Kemika Ruifu |
Nā mea | Nā kikoʻī | Nā hualoaʻa |
Ka nana aku | Kokoke Keʻokeʻo Paʻa Maʻemaʻe (Very Hygroscopic) | Hoʻopaʻa ʻia |
Ka hikiwawe | Hiki i ka wai | |
ʻIkepili | 1. Ka hoʻololi kino | Ka hopena maikaʻi |
2. IR: Kūlike me ka spectrum i loaʻa me RS | Hoʻopaʻa ʻia | |
3. Hoʻokō ka manawa paʻa o kahi kiʻekiʻe nui i nā noi | Hoʻopaʻa ʻia | |
Waiwai ʻakika | 1.5-2.5 | 1.9 |
Maopopo a me ke kala o ka hoʻonā | ʻAʻole ʻoi aku ka ʻeleʻele ma mua o RS Y1 | Hoʻopaʻa ʻia |
Wai na Karl Fischer | ≤3.00% | 2.2% |
Koena ma ka Ignition | ≤0.30% | 0.14% |
Nā Metala Kaumaha (Pb) | ≤10ppm | <10ppm |
Endotoxin | ≤0.3EU/mg | Hoʻopaʻa ʻia |
Microbiological | Pono e hoʻokō i ke koi | |
Huina Papa | ≤1000cfu/g | 55cfu/g |
Huna & Mold | ≤100cfu/g | 12cfu/g |
E. Coli | ʻAʻole/10g | Hoʻokō |
S. Aureus | ʻAʻole/10g | Hoʻokō |
Salmonella | ʻAʻole/10g | Hoʻokō |
S-Adenosyl-L-Homocystein | ≤0.50% | 0.10% |
Methithioadenosine | ≤1.00% | 0.24% |
Adenine | ≤0.50% | 0.09% |
Na mea pili | ||
ʻO nā mea haumia nui ʻē aʻe | ≤0.20% | 0.01% |
ʻO nā mea haumia ʻē aʻe | ≤0.50% | 0.006% |
(S,S) Isomer | >62.0% | 79.4% |
Butanedisulfonate | 46.0~49.0% (Kumu ma luna o ka maloʻo) | 47.5% |
Ademetionine | 50.0~53.0% (Kumu ma luna o ka maloʻo) | 52.1% |
Huina maʻiʻo | >97.5% (Ma muli o ka maloʻo) | 99.6% |
Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō me nā kikoʻī i hāʻawi ʻia | |
Ola Pahu | 2 makahiki i ka mālama pono ʻana |
Pūʻolo:ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
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Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Nā laʻana?Hāʻawi ka hapa nui o nā huahana i nā laʻana manuahi no ka loiloi maikaʻi, pono e uku ʻia ke kumukūʻai e nā mea kūʻai aku.
Hooia Hale Hana?Welina mai ka loiloi hale hana.E ʻoluʻolu e hoʻopaʻa manawa ma mua.
MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.
Manawa Hoʻouna? Inā i loko o ka waihona, ʻekolu lā hoʻouna ʻia.
Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.
Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.
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Nā Code Risk R49 - Hiki ke hoʻoulu i ka maʻi kanesa ma ka inhalation
R23 - He ʻona ma ka inhalation
R34 - Ke kumu o ke kuni
ʻO ka wehewehe palekana S53 - Hōʻalo i ka hoʻolaha - loaʻa nā ʻōlelo kuhikuhi kūikawā ma mua o ka hoʻohana ʻana.
S23 - Mai hanu i ka mahu.
S36/37/39 - E hoʻohana i nā lole pale kūpono, nā mīkina lima a me ka pale maka/maka.
S45 - Inā loaʻa ka pōʻino a i ʻole ka maikaʻi ʻole, e ʻimi koke i ka ʻōlelo aʻo kino (e hōʻike i ka lepili inā hiki.)
HS Code 2934999099
ʻO S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) kahi mea hoʻohui maʻamau i komo i ka hoʻoili pūʻulu methyl.Ua ʻike mua ʻia ʻo SAMe ma Italia e GL Cantoni i ka makahiki 1952, ʻo SAMe kahi mole i hana mau ʻia e nā cell ola a pau, hiki ke pale i ka maʻi maʻi ate, hoʻoikaika i ka cartilaginous tissue forming a concrescence, hiki ke kōkua i ke kaua ʻana i ke kaumaha, ka maʻi Alzheimer, ka maʻi ate, a me ka ʻeha o ke kino. ʻO ka osteoarthritis, ua ʻae ʻia ʻo SAME i kēia manawa he lāʻau lapaʻau koʻikoʻi e mālama ai i nā maʻi ate.I kēia mau lā, hoʻohana maʻamau ʻia ʻo SAMe i nā lāʻau lapaʻau, ʻoihana meaʻai mālama olakino ma ka mākeke kūloko a me ka honua.Kūʻai ʻia ʻo SAMe ma ʻAmelika Hui Pū ʻIa ma ke ʻano he meaʻai meaʻai.
1. ʻO S-Adenosyl-L-Methionine kahi meaʻai maikaʻi no ke akepaʻa, hiki ke pale i ka waiʻona, nā lāʻau lapaʻau a me ka pōʻino o ke akepaʻa;
2. He hopena koʻikoʻi ko S-Adenosyl-L-Methionine i ka maʻi maʻi maʻi maʻi a me nā kumu ʻē aʻe e hōʻino ai i ka ate, ka maʻi puʻuwai, ka maʻi kanesa a pēlā aku.
3. Ua ʻike ʻia ka maikaʻi o ka S-Adenosyl-L-Methionine e like me nā lāʻau lapaʻau no ka mālama ʻana i ka ʻāʻī a me ke kaumaha nui.
4. Ma ʻAmelika Hui Pū ʻIa, kūʻai ʻia ʻo SAM ma ke ʻano he meaʻai meaʻai ma lalo o ka inoa kūʻai aku ʻo SAM-e.Ua hōʻike kekahi mau haʻawina ʻo ka lawe mau ʻana i ka SAM hiki ke kōkua i ke kaua ʻana i ke kaumaha, ka maʻi ate, a me ka ʻeha osteoarthritis.Ua hōʻike ʻia kekahi mau hoʻokolohua lapaʻau he maikaʻi ia no ke kaumaha, kekahi mau maʻi ate a me ka osteoarthritis.ʻAʻole i hōʻoia ʻia nā hōʻailona ʻē aʻe.
5. Hoʻohana maʻi no ka hoʻomaikaʻi ʻana i ka hana ate.ʻO ka hui pū ʻana me L-DOPA no ka mālama ʻana i ka maʻi o Parkinson hiki ke hoʻomaikaʻi i ka pono o L-dopa a hōʻemi i nā hopena ʻaoʻao.Hiki ke ʻike ʻia ka ʻeha kūloko, ka hopohopo no ka manawa pōkole a me ka insomnia ma ke kahua o ka injection.
ʻO S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) he hopena maikaʻi hoʻi i ka maʻi o ka maʻi o ka maʻi, ka ʻiʻo fibrous, ka migraine a me nā maʻi ʻē aʻe, a he hopena liʻiliʻi.I ka hoʻomaka ʻana o ka makahiki 1970, ua hoʻohana ʻia ʻo SAMe ma ke ʻano he lāʻau lapaʻau no ka arthritis ma ʻEulopa.I ka makahiki 1999, ua ʻae ka US FDA i ka SAMe ma ke ʻano he huahana olakino a ua lilo ʻo ia i mea kūʻai maikaʻi loa ma ʻAmelika Hui Pū ʻIa.
Hoʻomākaukau nui ʻia ʻo S-Adenosyl-L-Methionine e ka synthesis chemical, fermentation a me ka hoʻololi enzymatic.ʻO ke ʻano fermentation ʻo ia ka hoʻohui ʻana i ka L-Methionine precursor i ke kumu kumu i loaʻa nā kumu C a me N, a hiki ke loaʻa ka nui o S-Adenosylmethionine ma o ka culturing microbial cell.ʻO kēia ke ala nui no ka hana ʻenehana o S-Adenosylmethionine.I waena o lākou, hiki ke loaʻa i nā microorganisms i hoʻohana ʻia no ka fermentation ma o ka screening a i ʻole recombination hana kūkulu ʻana, i hoʻopaʻa ʻia i nā ʻatikala a me nā patent ma ka home a ma waho.Ua hāʻawi kekahi mau haʻawina i kahi ʻano hoʻomākaukau o S-adenosylmethionine, me ka hoʻohana ʻana i ka polyhydroxy organic reagents e pale i ka hana o ka enzyme, me ka hoʻohana ʻana i ka adenosine triphosphate precursor, L-Methionine a me nā ion phosphate ma ke ʻano he substrates, glucose a / a me ka maltose ma ke ʻano he mea hāʻawi ikehu, hoʻohui i kahi haku mele. o nā ʻiona metala, a me ka hoʻohana ʻana i kahi kānana hana permeable e hoʻopololei i ka hana ʻana o S-Adenosylmethionine i loko o nā cell holoʻokoʻa.Ke hoʻohana nei i ka hoʻohui ʻana o nā ion metala e hoʻoponopono i ke kahe metabolic e hoʻomaikaʻi i ka pono o ka hoʻohui ʻana i ka ikehu, e hoʻohui i nā reagents organik e pale i ka hana o ka bacteria a me nā enzymes, me ka hoʻohana ʻana i kahi kānana hana permeable e hoʻomākaukau ai i ka S-Adenosylmethionine, e hoʻopōkole i ka manawa synthesis, a e hōʻiliʻili i ka huahana ma waho o ke kelepona, hiki ke mālama i ke kumukūʻai o ka hoʻokaʻawale ʻana a maʻalahi i nā ʻanuʻu hana.
Ua kaupalena ʻia ka ʻike e pili ana i ka palekana lōʻihi o S-Adenosyl-L-Methionine no ka mea ua lawe ka poʻe i komo i ka hapa nui o nā haʻawina no nā manawa pōkole wale nō.Eia naʻe, i hoʻokahi haʻawina o ka maʻi ate pili i ka waiʻona, ua lawe nā mea komo i ka S-Adenosyl-L-methionine no 2 mau makahiki;i loko o kēlā haʻawina, ʻaʻohe hopena koʻikoʻi i hōʻike ʻia.
ʻAʻole pono ka poʻe me ka maʻi bipolar (he maʻi i ʻike ʻia e ka loli ʻana o ka naʻau, mai ke kaumaha a hiki i ka mania) ʻaʻole pono e lawe i ka SAMe no ko lākou mau hōʻailona kaumaha koe wale nō ma lalo o ka mākaʻikaʻi ʻana o kahi mea mālama ola no ka mea hiki i ka SAMe ke hoʻonui i nā hōʻailona o ka mania.
ʻOiai ua hoʻohana ʻia ʻo S-Adenosyl-L-Methionine e mālama i ka cholestasis i ka wā hāpai, ʻaʻole i hoʻokumu ʻia kona palekana i ka wā hāpai.
Hiki i ka SAMe ke hoʻemi i nā hopena o levodopa (L-dopa), he lāʻau lapaʻau i hoʻohana ʻia e mālama i ka maʻi o Parkinson.Hiki nō hoʻi iā SAMe ke launa pū me nā lāʻau lapaʻau a me nā mea hoʻohui meaʻai e hoʻonui ai i ke kiʻekiʻe o ke serotonin (he mea kemika i hana ʻia e nā pūnana nerve), e like me nā antidepressants, L-tryptophan, a me St. John's wort.
Aia kekahi mana'o no'ono'o e pili ana i ka ho'ohana 'ana i ka SAMe e ka po'e ma'i immunocompromised (e like me ka po'e ma'i HIV).ʻO ka poʻe i hoʻopilikia i ka immunocompromised ka pilikia no ka maʻi Pneumocystis carinii, a hoʻonui ʻo SAMe i ka ulu ʻana o kēia microorganism.
ʻAʻole maʻamau nā hopena ʻaoʻao o SAMe, a i ka wā e loaʻa ai, he mau pilikia liʻiliʻi lākou e like me ka nausea a i ʻole nā huhū digestive.