Anastrozole CAS 120511-73-1 API Factory High Quality
Hāʻawi Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Anastrozole
CAS: 120511-73-1
inoa | Anastrozole |
Nā huaʻōlelo like | Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile |
Helu CAS | 120511-73-1 |
Helu CAT | RF-API74 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C17H19N5 |
Kaumaha Molecular | 293.37 |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i DMSO a me Ethanol |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
ʻIkepili A | Kūlike ʻo IR/MS me ka maʻamau kuhikuhi |
ʻIkepili B | ʻO ka HPLC a me ke ʻano kiʻekiʻe: E like me ka kuhikuhi |
Lae hehee | 81.0~84.0 ℃ |
Waiwai (na KF) | ≤0.30% |
Koena ma ka Ignition | ≤0.10% |
Nalo ma ka maloo | ≤0.50% |
Nā Metala Kaumaha | ≤10ppm |
Na mea pili | |
haumia A | ≤0.10% |
haumia B | ≤0.20% |
haumia C | ≤0.20% |
haumia D | ≤0.10% |
haumia E | ≤0.10% |
Hoʻokahi 'ē aʻe haumia | ≤0.10% |
Huina paumaele | ≤0.50% |
Nā mea hoʻoheheʻe koena | |
Cyclohexane | ≤0.30% |
Ethyl Acetate | ≤0.50% |
Hoʻāʻo | 98.0%~102.0% (ma ke kumu maloʻo) |
Ola Pahu | 24 mahina |
Kūlana hoʻāʻo | ʻOihana Kūlana;ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP). |
Hoʻohana | Lapaʻau no ka maʻi maʻi umauma |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Anastrozole (CAS 120511-73-1), he non-steroidal, kolu o ka hanauna achiral triazole derivative i kūʻai ʻia e like me ARIMIDEX® e AstraZeneca Pharmaceuticals LP1.ʻO ia kekahi o ke kolu o ka hanauna aromatase inhibitor kahi mea hoʻokūkū hoʻokūkū nui a koho i ka aromatase, no laila ke kāohi nei i ka hoʻololi ʻana o ka testosterone i estradiol a me androstenedione i estrone.Hoʻopili ʻia ka enzyme aromatase ma o ka hoʻokūkū hoʻokūkū o ka aromatase i ka hemegroup o cytochrome P450, e hoʻemi ana i ka biosynthesis estrogen i nā ʻiʻo peripheral o ke kino a me ka umauma.
He lāʻau lapaʻau maʻamau ʻo Anastrozole no ka maʻi maʻi umauma mua.E like me nā mea ʻokoʻa aromatase ʻē aʻe, ʻo kāna hopena koʻikoʻi koʻikoʻi ka piʻi ʻana o ka haʻihaʻi o ka iwi, no ka anastrozole i kaupalena ʻia i ka wā mālama.He ʻano ʻawaʻawa kona ke hoʻohālikelike ʻia me ka chemotherapy;akā naʻe, ua ʻike ʻia ka nui o nā poʻe maʻi i mālama ʻia me ka anastrozole i hoʻopiʻi i nā hōʻailona hui ma mua o ka mea i manaʻo ʻia, ʻoi aku ka ʻoʻoleʻa kikohoʻe e like me ka rheumatoid arthritis.ʻO kekahi mau hoʻokolohua lapaʻau o anastrozole no nā wahine postmenopausal me ka maʻi maʻi umauma ma ʻEulopa a me ʻAmelika Hui Pū ʻIa i hōʻike i nā maʻi musculoskeletal ma ke ʻano he hopena ʻino.ʻO Anastrozole (Arimidex®) he mea hoʻopaneʻe aromatase i ʻae ʻia i ka EU, ka US a me nā ʻāina ʻē aʻe o ka honua no ka hoʻohana ʻana ma ke ʻano he lapaʻau adjuvant i nā wahine postmenopausal me ka maʻi maʻi umauma maʻi maʻi.Ua ʻae ʻia ma ka EU a me nā ʻāina ʻē aʻe o ka honua no ka hoʻomau ʻana i ka mālama adjuvant i nā wahine i loaʻa mua i ka 2-3 makahiki o ka adjuvant tamoxifen lapaʻau no ka maʻi maʻi umauma.