ʻO Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Mea Hoʻolako Mea Hana Argatroban Nā Kūwaena Pili:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
Inoa Kimia | Argatroban |
Nā huaʻōlelo like | ʻO Argatroban Anhydrous |
Helu CAS | 74863-84-6 |
Helu CAT | RF-API67 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C23H36N6O5S |
Kaumaha Molecular | 508.63 |
Lae hehee | 188.0~189.0 ℃ |
Lae paila | 801.3ºC ma 760 mmHg |
ʻO ka mānoanoa | 1.47 g/cm3 |
Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
ʻIke HPLC | ʻO ka manawa paʻa o ka piko kumu i loaʻa mai ka hoʻonā ho'āʻo e kūlike me ka mea i loaʻa mai ka solution maʻamau, e like me ka hoʻāʻo ma Assay |
ʻIkepili IR | Kūlike me ka IR Spectrum o AG RS |
Hōʻike UV | Ma ka hawewe 259nm a me 332nm ka lōʻihi o ka nalu, pono e loaʻa ka nui o ka absorption |
Wai | 2.5-4.5% |
ʻO ke kala a me ka mālamalama | Pono e hoʻomaʻemaʻe nā kala |
Pili i na mea | |
ʻO ka haumia A + ʻO ka haumia H | ≤0.10% |
haumia B | ≤0.10% |
Ka haumia C + Ka haumia E | ≤0.10% |
haumia D | ≤0.10% |
haumia I | ≤0.10% |
Bach o ka haumia ʻole i hōʻike ʻia | ≤0.10% |
Huina paumaele | ≤0.30% |
Nā mea hoʻoheheʻe koena | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl Acetate | ≤5000ppm |
Enantiomer (HPLC) | ≤0.10% |
Laki ʻIsomer (HPLC) | 30.0%-40.0% |
Klorida | ≤0.01% |
Koena ma ka Ignition | ≤0.10% |
Nā Metala Kaumaha | ≤10ppm |
Nā Endotoxins Bacterial | <5EU/mg |
Palena Microbial | TAMC ≤1000 cfu/g |
Hoʻāʻo | 98.0%-102.0% (ma ke kumu anhydrous) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | API, ʻAi ʻAi ʻAi ʻAi ʻAi ʻAi ʻAi ʻAi ʻAi |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana alakaʻi a me ka mea hoʻolako o Argatroban (CAS: 74863-84-6) me ke kūlana kiʻekiʻe, API.
ʻO Argatroban (CAS: 74863-84-6) he mea hou synthetic antithrombotic agent pono i ka mālama anticoagulation iā lākou ischemic stroke a hoʻolaha i ka intravascular coagulation.He anticoagulant ʻo ia kahi mole liʻiliʻi pololei thrombin inhibitor.I ka makahiki 2000, ua laikini ʻia ka argatroban e ka Food and Drug Administration (FDA) no ka prophylaxis a i ʻole ka mālama ʻana i ka thrombosis i nā maʻi me ka thrombocytopenia (HIT).I ka makahiki 2002, ua ʻae ʻia ia no ka hoʻohana ʻana i ka wā o ka hoʻoponopono coronary percutaneous i nā poʻe maʻi i loaʻa iā HIT a i ʻole ka pilikia no ka hoʻomohala ʻana.Ma 2012, ua ʻae ʻia e ka MHRA ma UK no ka anticoagulation i nā maʻi me ka heparin-induced thrombocytopenia Type II (HIT) e koi ana i ka antithrombotic therapy parenteral.