Aripiprazole Intermediate CAS 129722-34-5 Maʻemaʻe >98.0% (HPLC)
Hāʻawi ka mea hana i nā mea waena o Aripiprazole me ka maʻemaʻe kiʻekiʻe
Aripiprazole API CAS 129722-12-9
1-(2,3-Dichlorophenyl)piperazine Hydrochloride CAS 119532-26-2
7-Hydroxy-3,4-Dihydro-2(1H)-Quinolinone CAS 22246-18-0
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone CAS 129722-34-5
| Inoa Kimia | 7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone |
| Nā huaʻōlelo like | 7-(4-Bromobutoxy)-3,4-Dihydroquinolin-2(1H)-hoʻokahi;7-(4-Bromobutoxy) -1,2,3,4-Tetrahydro-2-Oxoquinoline;3,4-Dihydro-7-(4-Bromobutoxy)-2(1H)-Quinolinone;Aripiprazole haumia 3 |
| Helu CAS | 129722-34-5 |
| Helu CAT | RF-PI2269 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C13H16BrNO2 |
| Kaumaha Molecular | 298.18 |
| ʻO ka mānoanoa | 1.383 g/cm3 |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Keokeo a i ʻole Melemele Puka Puka |
| Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) |
| Lae hehee | 110.0~114.0 ℃ |
| Nalo ma ka maloo | <1.00% |
| Koena ma ka Ignition | <0.50% |
| Nā Metala Kaumaha (e like me Pb) | ≤20ppm |
| Proton NMR Spectrum | Kūlike i ka hoʻolālā |
| Kūlana hoʻāʻo | Kūlana ʻoihana |
| Hoʻohana | Kūwaena o Aripiprazole (CAS: 129722-12-9) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
7-(4-Bromobutoxy)-3,4-Dihydro-2(1H)-Quinolinone (CAS: 129722-34-5) he mea waena i ka synthesis o Aripiprazole (CAS: 129722-12-9).He huahana hoʻohaʻahaʻa i nā papa Aripiprazole.Aripiprazole (Abilify).ʻO ka mea hou loa, longactingaripiprazole (he arylpiperazine quinolinone derivative), ʻike ʻia he agonist ʻāpana o nā mea loaʻa D2 (ʻo ia hoʻi, hoʻoulu i kekahi mau mea loaʻa D2 i ka wā e pale ana i nā poʻe ʻē aʻe e pili ana i ko lākou wahi i loko o ka lolo a me ka neʻe o ka lāʻau).Aia ka bioavailability o Aripiprazole ma kahi o 87%, me ke kiʻekiʻe kiʻekiʻe o ka plasma koko i loaʻa ma 3 a 5 mau hola ma hope o ka lawe ʻana.Hoʻopili ʻia ia e ka dehydrogenation, oxidative hydroxylation, a me N-dealkylation, i hoʻopili nui ʻia e ka hepatic CYPs 3A4 a me 2D6.No ka mālama ʻana i ka schizophrenia a me nā maʻi psychotic pili.ʻO kahi dopamine D2-receptor antagonist koho me ka dopamine autoreceptor agonist hana.Antipsychotic.
