Atazanavir CAS 198904-31-3 Maʻemaʻe ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor
Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Atazanavir
CAS: 198904-31-3
HIV-1 Protease Inhibitor
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | ʻO Atazanavir |
Nā huaʻōlelo like | BMS-232632 |
Helu CAS | 198904-31-3 |
Helu CAT | RF-API70 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C38H52N6O7 |
Kaumaha Molecular | 704.86 |
Lae hehee | 207.0~209.0 ℃ |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia ma DMSO;ʻAʻole hiki ke hoʻonā i ka wai |
Waihona Loihi | E mālama i ka wā lōʻihi ma -20 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pauda keʻokeʻo |
Puka | Kumu Kuokoa |
Nalo ma ka maloo | ≤0.50% |
Koena ma ka Ignition | ≤0.20% |
Nā Metala Kaumaha | ≤20ppm |
haumia A | ≤0.10% |
haumia B | ≤0.10% |
Hoʻokahi haumia | ≤0.20% |
Huina paumaele | ≤1.0% |
Maʻemaʻe/Ana Hana Hana | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | HIV-1 Protease Inhibitor Anti-HIV |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
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ʻO Atazanavir (CAS 198904-31-3) he lāʻau antiretroviral, novel a me ka lāʻau azapeptide ikaika o ka papa protease inhibitor (PI).Ua kūʻai ʻia ma lalo o ka inoa kalepa ʻo Reyataz.E like me nā antiretrovirals ʻē aʻe, hoʻohana ʻia ia e mālama i ka maʻi o ke kanaka immunodeficiency virus type 1 (HIV-1) protease enzyme me ka inhibition mau Ki o 66 nmol/L a hoʻopaʻa pū i ka hoʻopiʻi viral o HIV-1 me 50% ka manaʻo kūpono EC50 mai. 2.6 a 5.3 nmol/L.Hoʻopaʻa ʻo Atazanavir i ka protease HIV-1 e pale ana i ka wehe ʻana o ka gag a me ka gag-pol polyproteins, ka mea i hopena i ka hoʻokumu ʻana i nā virion ʻaʻole i oʻo i loko o nā sela i hoʻopili ʻia e ka HIV-1.Loaʻa i ka Atazanavir kahi ʻano kemika C-2 symmetric ʻē aʻe a me ka mana antiretroviral maʻamau i nā maʻi HIV like ʻole i hoʻohālikelike ʻia me nā mea hoʻopanee protease ʻē aʻe, me Indinavir, Nelfinavir, Ritonavir, Saquinavir a me Amprenavir.Hoʻokaʻawale ʻia ʻo Atazanavir mai nā PI ʻē aʻe i hiki ke hāʻawi ʻia i hoʻokahi lā i kēlā me kēia lā a he liʻiliʻi ka hopena i ka ʻike lipid o ka mea maʻi.E like me nā mea pale protease ʻē aʻe, hoʻohana ʻia ia me nā lāʻau lapaʻau HIV ʻē aʻe.ʻO Atazanavir kahi mea hoʻopaneʻe protease HIV hou ʻo azapeptide.Antiviral.Lawe ʻia ma ka waha i hoʻokahi manawa i ka lā.
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