Atazanavir Sulfate CAS 229975-97-7 Maʻemaʻe ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor
Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Atazanavir Sulfate
CAS: 229975-97-7
HIV-1 Protease Inhibitor
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | ʻO Atazanavir Sulfate |
Nā huaʻōlelo like | BMS-232632 Sulfate |
Helu CAS | 229975-97-7 |
Helu CAT | RF-API71 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C38H52N6O7.H2SO4 |
Kaumaha Molecular | 802.93 |
Lae hehee | 195.0~198.0 ℃ |
Ka hikiwawe | ʻAʻole hiki ke hoʻoheheʻe i ka wai, hiki ke hoʻoheheʻe ʻia i DMSO |
Waihona Loihi | E mālama i ka wā lōʻihi ma -20 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pada keʻokeʻo a i ʻole keʻokeʻo |
Sulfate | 12.0-12.5% |
Nalo ma ka maloo | ≤0.50% |
Koena ma ka Ignition | ≤0.10% |
Nā Metala Kaumaha | ≤20ppm |
Hoʻokahi haumia | ≤0.30% |
Huina paumaele | ≤1.0% |
Maʻemaʻe/Ana Hana Hana | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | HIV-1 Protease Inhibitor Anti-HIV |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) he ʻano paʻakai sulfate o atazanavir i koho nui ʻia i ka HIV-1 protease inhibitor, ʻo ia ka mea hoʻopaneʻe protease mua i ʻae ʻia no ka hoʻoponopono ʻana i hoʻokahi lā.ʻO Atazanavir Sulfate kahi pani a me ka mea paʻa o CYP3A4, a me ka mea hoʻopaneʻe a me ka mea hoʻoulu i ka P-glycoprotein (P-gp).ʻO Atazanavir Sulfate kekahi mea hoʻopaneʻe SARS-CoV 3CLpro me kahi IC50 o 3.49 μM.ʻO Atazanavir Sulfate he azapeptide a me HIV-protease inhibitor i hoʻohana ʻia i ka mālama ʻana i nā maʻi HIV a me AIDS i hui pū ʻia me nā Agen Anti-HIV ʻē aʻe, ua kūkulu ʻia a hoʻolaha ʻia e Bristol-Myers Squibb (BMS), ma lalo o ka laikini honua mai Novartis, no ka mālama ʻana i ka maʻi HIV.Ua hoʻokuʻu ʻia ʻo Atazanavir ma US ʻo Reyataz™ i Iulai 2003. Antiviral.Ua hōʻike ʻia ʻo Atazanavir e ʻoi aku ka ikaika ma mua o nā ʻelima mau mea hoʻopaneʻe protease HIV-1 i kēia manawa.Hoʻopaʻa koho ʻo Atazanavir i ka hoʻoili ʻana o ka viral Gag a me Gag-Pol polyproteins i nā maʻi HIV-1 ma o ka hoʻopaʻa ʻana i ka pae hana o ka HIV-1 protease, pēlā e pale ai i ka hoʻokumu ʻana o nā virion makua.ʻAʻole ikaika ʻo Atazanavir i ka maʻi HIV-2.