Azithromycin Dihydrate CAS 117772-70-0 Assay 945~1030μg/mg API Hale Hana Kiʻekiʻe
Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Azithromycin Dihydrate
CAS: 117772-70-0
API Kūlana Kiʻekiʻe, Hana Hana Kūʻai
Inoa Kimia | ʻO Azithromycin Dihydrate |
Helu CAS | 117772-70-0 |
Helu CAT | RF-API95 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C38H72N2O12 |
Kaumaha Molecular | 748.99 |
Lae hehee | 126 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keokeo a aneane keokeo pauda |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i ka Anhydrous Ethanol a me ka Methylene Chloride, ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai. |
ʻIkepili IR/HPLC | Kūlike me ka maʻamau kuhikuhi Azithromycin |
Crystallinity | Kū i nā koi |
pH | 9.0~11.0 |
Hoʻololi Optical kikoʻī | -45.0°~-49.0° |
Nā Metala Kaumaha | ≤20ppm |
Wai | 4.0-5.0% |
Koena ma ka Ignition | ≤0.20% |
Na mea pili | |
Azithromycin-N-oxide | ≤0.50% |
3'-(NN-Didemethyl)Azithromycin(aminozaithromycin) | ≤0.50% |
ʻO ka hui pili ʻo Azithromycin F | ≤0.50% |
Desosaminylazithromycin | ≤0.30% |
N-Demethylazithromycin | ≤0.70% |
ʻO Azithromycin-C | ≤0.50% |
3'-De(dimethylamino)-3'-oxoazithromycin | ≤0.50% |
ʻO Azaerythromycin A | ≤0.50% |
ʻO Azithromycin Impurity P | ≤0.20% |
2-Desetyl-2-Propylazithromycin | ≤0.50% |
3'-N-DemETHYL-3'n-[(4-methylphenyl)sulfonyl]Azithromycin | ≤0.50% |
ʻO Azithromycin-B | ≤1.0% |
ʻO nā mea haumia ʻole i hōʻike ʻia | ≤0.20% |
Huina paumaele | ≤3.0% |
Nā mea hoʻoheheʻe koena | |
Methanol | ≤0.30% |
Ethanol | ≤0.05% |
Acetone | ≤0.50% |
Chloroform | ≤0.006% |
Hoʻāʻo | 945~1030μg/mg (C38H72N2O12 ma ke kumu anhydrous) |
Ola Pahu | 24 mahina |
Kūlana hoʻāʻo | USP Kūlana |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Azithromycin kahi lāʻau lapaʻau macrolide ākea me ka hapalua o ke ola a me ke kiʻekiʻe o ke komo ʻana o ka ʻiʻo 3. Ua ʻae mua ʻia e ka FDA i ka makahiki 1991. Hoʻohana nui ʻia ia no ka mālama ʻana i nā maʻi hanu, enteric a me genitourinary maʻi a hiki hoʻohana ʻia ma kahi o nā macrolides ʻē aʻe no kekahi mau maʻi i hoʻouna ʻia i ka moekolohe a me nā maʻi enteric.He mea pili i ka erythromycin.Kāohi ʻo Azithromycin i ka ulu ʻana o ka maʻi bacteria ma ke keʻakeʻa ʻana i kā lākou protein synthesis.Hoʻopaʻa ia i ka subunit 50S o ka ribosome bacteria, no laila ke kāohi nei i ka unuhi ʻana o ka mRNA.ʻAʻole pili ʻia ka synthesis acid nucleic.