Bacitracin Zinc CAS 1405-89-6 Manawa ≥70 IU/mg Peptide Antibiotic Factory
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o Bacitracin Zinc (Zinc Bacitracin) (CAS: 1405-89-6) me ke ʻano kiʻekiʻe.Hiki iā mākou ke hāʻawi i ka COA, ka lawe ʻana i ka honua holoʻokoʻa, nā mea liʻiliʻi a me ka nui i loaʻa.Inā makemake ʻoe iā Bacitracin Zinc (Zinc Bacitracin),Please contact: alvin@ruifuchem.com
| Inoa Kimia | Bacitracin Zinc |
| Nā huaʻōlelo like | Bacitracin Zinc Salt;Zinc Bacitracin |
| Kūlana Kūʻai | I loko o ka waihona, hana hiki ke 10 tona no ka makahiki |
| Helu CAS | 1405-89-6 |
| ʻĀpana Molekala | C66H101N17O16SZn |
| Kaumaha Molecular | 1486.07 |
| Lae hehee | 250 ℃ (Dek.) |
| Hiki i ka wai | 5.1 g/L |
| COA & MSDS | Loaʻa |
| Laʻana | Loaʻa |
| Brand | Kemika Ruifu |
| Nā mea | Nā kikoʻī | Nā hualoaʻa |
| Ka nana aku | Keʻokeʻo a i ʻole ʻulaʻula melemele-hina a i ʻole ka pauka beige | Kūlike |
| ʻIkepili | E hoʻokō i nā koi | Hōʻike i ka hopena maikaʻi |
| pH | 6.0-7.5 | 7.1 |
| Nalo ma ka maloo | ≤5.0% | 2.7% |
| Zinc (mea maloʻo) | 4.0%~6.0% | 4.20% |
| Ka mana | ≥70 IU/mg Microbial Assay (Dried Base) | 71 IU/mg |
| ʻO ka maʻi o Bacitracin A | ≥40.0% | 58.2% |
| Maʻiʻo o Active Bacitracin | ≥70.0% (Bacitracin A, B1, B2, a me B3) | 86.1% |
| Ka palena o nā Peptides Eluting Mua | ≤20.0% | 7.6% |
| Ka palena o Bacitracin F | ≤6.0% | 1.1% |
| Huina Aerobic Viable | <100 CFU/gram | Kūlike |
| Ka hopena | Kūlike ka Huahana i nā Kūlana USP44 | |
| Hoohana Nui | Antibiotic Peptide | |
Pūʻolo:ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E hoʻopaʻa paʻa i ka pahu a mālama i loko o kahi hale kūʻai maloʻo a maloʻo (2 ~ 8 ℃) a me kahi hale kūʻai maikaʻi mai nā mea like ʻole.E pale i ka malamalama a me ka wai.
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Bacitracins, paʻakikī zinc.
Bacitracins zinc complex [1405-89-6].
» ʻO Bacitracin Zinc ka paʻakikī zinc o ka bacitracin, nona ka hui ʻana o nā polypeptides antimicrobial, ʻo nā mea nui he bacitracins A, B1, B2, a me B3.Loaʻa ka mana o ka liʻiliʻi ma mua o 65 Bacitracin Units i ka mg, helu ʻia ma ke kumu maloʻo.ʻAʻole i emi iho ma lalo o 4.0 pākēneka a ʻaʻole ʻoi aku ma mua o 6.0 pākēneka o ka zinc (Zn), i helu ʻia ma ke kumu maloʻo.
Hoʻopili a mālama ʻia - E mālama i loko o nā pahu paʻa, a mālama i kahi anuanu.
Lepili-Lepili ia mea e hōʻike e hoʻohana ʻia i ka hana ʻana i nā lāʻau lapaʻau nonparenteral wale nō.Ma kahi i hoʻopaʻa ʻia no ka hoʻohui ʻana i ka lāʻau lapaʻau, e lepili iā ia i mea e hōʻike ai ʻaʻole ia he sterile a ʻaʻole hiki ke hōʻoia i ka ikaika no ka lōʻihi o 60 mau lā ma hope o ka wehe ʻana, a e hōʻike i ka helu o nā ʻāpana Bacitracin i ka milligram.Ma kahi i manaʻo ʻia e hoʻohana ʻia i ka hoʻomākaukau ʻana i nā ʻano hoʻohālikelike sterile, ʻōlelo ka lepili he sterile a pono e hoʻokō ʻia i ka hana hou ʻana i ka wā o ka hoʻomākaukau ʻana i nā ʻano hoʻohālikelike sterile.
Nā kūlana hōʻike USP <11>-
USP Bacitracin Zinc RS
ʻike-
A: Thin-Layer Chromatographic Identification Test <201BNP>: hoʻokō i nā koi.
B: Hoʻokō ia i nā koi o ke kaʻina hana chromatographic wai i ka hoʻāʻo no ka Composition.
Sterility <71>-Ma kahi e ʻōlelo ai ka lepili he sterile, ua hoʻokō ʻo ia i nā koi ke hoʻāʻo ʻia e like me ke kuhikuhi ʻana no ka Membrane Filtration ma lalo o ka Test for Sterility of the Product to be Examined, koe wale nō ka hoʻohana ʻana i ka Fluid A i kēlā me kēia L i hoʻohui ʻia 20 g of edetate disodium.
pH <791>: ma waena o 6.0 a me 7.5, i loko o kahi solution (saturated) i loaʻa ma kahi o 100 mg no mL.
Nalo ma ka maloʻo <731>-Moloo ma kahi o 100 mg i loko o ka pahu capillary-stoppered i loko o ka vacuum ma 60 no 3 mau hola: ʻaʻole e nalowale ma mua o 5.0% o kona kaumaha.
Zinc maʻiʻo- [nota-ʻO ka hoʻomākaukau maʻamau a me ka hoʻomākaukau hoʻāʻo hiki ke hoʻoheheʻe ʻia me ka 0.001 N hydrochloric acid, inā pono, e loaʻa ai nā hopena o nā koina kūpono, hiki ke hoʻololi ʻia i ka laina laina a i ʻole ka hana o ka mea kani.]
Hoʻomākaukau maʻamau-E hoʻololi i ka 3.11 g o ka zinc oxide, i kaupaona pololei ʻia, i kahi pahu volumetric 250-mL, e hoʻohui i 80 mL o 1 N hydrochloric acid, mahana e hoʻoheheʻe, hoʻoluʻu, hoʻoheheʻe me ka wai i ka nui, a hui.Loaʻa i kēia hopena he 10 mg o ka zinc no ka mL.E hoʻoheheʻe hou i kēia hopena me ka 0.001 N hydrochloric acid no ka loaʻa ʻana o nā hoʻomākaukau maʻamau i loaʻa ka 0.5, 1.5, a me 2.5 µg o ka zinc no ka mL.
Hoʻomākaukau hoʻāʻo-E hoʻoneʻe ma kahi o 200 mg o Bacitracin Zinc, i kaupaona pololei ʻia, i kahi pahu volumetric 100-mL.E hoʻoheheʻe i loko o ka 0.01 N hydrochloric acid, e hoʻoheheʻe me ka mea hoʻokahi i ka leo, a hui pū.Pipet 2 mL o kēia haʻina i loko o ka pahu volumetric 200-mL, e hoʻoheheʻe me 0.001 N hydrochloric acid i ka nui, a hui.
Kaʻina hana-E hoʻoholo like i ka absorbances o ka Standard hoomakaukau a me ka ho'āʻo hoʻomākaukau ma ka zinc resonance laina o 213.8 nm, me ka atomic absorption spectrophotometer kupono (e nana Spectrophotometry a me Light-scattering <851>), lako me ka zinc hollow-cathode kukui a he lapalapa ea-acetylene, e hoʻohana ana i ka 0.001 N hydrochloric acid ma ke ʻano he hakahaka.E kahakii i ka hoomoe ana o na mea hoomakaukau ma'amau me ka no'ono'o, ma µg no mL, o ka zinc, a e kaha i ka laina pololei i kupono loa i na kiko ekolu.Mai ka pakuhi i loaʻa mai, e hoʻoholo i ka neʻe ʻana, ma µg no mL, o ka zinc ma ka hoʻomākaukau hoʻāʻo.E helu i ka maʻiʻo o ka zinc, ma ka pākēneka, ma ka ʻāpana o ka Bacitracin Zinc i lawe ʻia e ke kumu:
1000C / W
i loko o ka C ka hoʻopaʻa ʻana ma µg no mL, o ka zinc ma ka hoʻomākaukau hoʻāʻo;a ʻo W ka paona, ma ka mg, o ka hapa o Bacitracin Zinc i lawe ʻia.
Hui-
Buffer- E hoʻoheheʻe i 34.8 g o ka potassium phosphate, dibasic, i 1 L o ka wai.Hoʻoponopono me ka 27.2 g o ka potassium phosphate, monobasic, hoʻoheheʻe ʻia i 1 L o ka wai, i kahi pH o 6.0.
Māhele Mobile-E hoʻomākaukau i ka hui ʻana o ka methanol, ka wai, Buffer, a me ka acetonitrile (26:15:5:2).E hui maikaʻi, a me ka degas.
Diluent-Dissolve 40 g o ka edetate disodium i 1 L o ka wai.Hoʻoponopono me ka sodium hydroxide dilute i kahi pH o 7.0.
ʻO ka hoʻonā kūpono o ka ʻōnaehana-Hoʻoheheʻe i ka nui o ka USP Bacitracin Zinc RS i kaupaona pololei ʻia ma ka Diluent e loaʻa ai kahi hopena me ka helu nominal ma kahi o 2.0 mg no ka mL.
Hōʻike i ka hopena paepae-E hoʻoheheʻe i ka nui, me ka wai, kahi leo kūpono o ka ʻōnaehana kūpono e loaʻa ai kahi hopena me ka ʻike ʻike ʻia o 0.01 mg no mL.
ʻO ka hoʻonā ʻike kiʻekiʻe-E hoʻopau i ka nui o ka USP Bacitracin Zinc RS i kaupaona ʻia i loko o kahi puʻupuʻu kūpono o ka Diluent e loaʻa ai kahi hopena me ka manaʻo nominal ma kahi o 2.0 mg no ka mL.E wela i ka ʻauʻau wai paila no 30 mau minuke.Hoʻolili i ka lumi wela.
Hoʻonā hoʻāʻo-E hoʻopau i ka nui o ka Bacitracin Zinc i kaupaona pono ʻia i ka Diluent no ka loaʻa ʻana o kahi hopena me ka manaʻo nominal ma kahi o 2.0 mg no ka mL.
Pūnaehana Chromatographic (e nānā i ka Chromatography <621>)-Ua hoʻolako ʻia ka chromatograph wai me kahi mea ʻike absorbance a me kahi kolamu 4.6- × 250-mm ka hopena i loaʻa iā 5-µm packing L1.ʻO 1.0 mL ka nui o ke kahe i kēlā me kēia minuke.E hoʻonoho i ka lōʻihi nalu o ka mea ʻike ma 300 nm.Inject ma kahi o 100 µL o ka Peak identification solution, a e ʻike i kahi o ka bacitracin F, he haumia i ʻike ʻia, me ka hoʻohana ʻana i ka manawa paʻa pili i hōʻike ʻia ma ka Papa 1.
Papa 1
Manawa Hoʻopaʻa Paʻa Pili (kokoke)
Bacitracin C1 0.5
Bacitracin C2 0.6
Bacitracin C3 0.6
Bacitracin B1 0.7
ʻO Bacitracin B2 0.7
ʻO Bacitracin B3 0.8
ʻO Bacitracin A 1.0
ʻO Bacitracin F 2.4
E hoʻololi i ka lōʻihi nalu o ka mea ʻike a hoʻonoho iā 254 nm.Chromatograph i ka ʻōnaehana kūpono kūpono, a hoʻopaʻa i nā pane kiʻekiʻe e like me ke kuhikuhi ʻana no ke Kaʻina hana: e ʻike i nā piko o nā mea ikaika loa o ka bacitracin (bacitracins A, B1, B2 a me B3), nā peptides eluting mua (nā mea e hoʻoheheʻe ʻia ma mua o ka piko ma muli o ka bacitracin B1 ) a me ka haumia, bacitracin F, me ka hoʻohana ʻana i nā koina manawa paʻa pili i hāʻawi ʻia ma ka Papa 1. E helu i ka ratio peak-to-valley me ka hoʻohana ʻana i ke ʻano:
Hp / HV
ʻo ia ka Hp ke kiʻekiʻe ma luna o ka palena kumu o ka piko ma muli o ka bacitracin B1;a ʻo HV ke kiʻekiʻe ma luna o ka palena haʻahaʻa o ka piko e hoʻokaʻawale ana i ka piko bacitracin B1 mai ka piko ma muli o ka bacitracin B2.ʻAʻole emi ka ratio peak-to-valley ma mua o 1.2.
Kaʻina hana-Hoʻokaʻawale i nā puke like (100 µL) o ka mea hoʻoheheʻe, hoʻonā hoʻāʻo, a me ka hoʻonā paepae hōʻike.E hoʻopaʻa i nā chromatograms ma kahi o ʻekolu manawa o ka manawa paʻa o ka bacitracin A. E ʻike i nā piko me ka hoʻohana ʻana i nā manawa paʻa pili i hōʻike ʻia ma ka Papa 1. E ana i nā ʻāpana kiʻekiʻe o nā piko āpau i ka hoʻonā Hoʻo.[note-Hoʻowahāwahā i kekahi piko i loko o ka ho'āʻo ho'āʻo i loaʻa kahi ʻāpana liʻiliʻi ma mua o ka ʻāpana o ka bacitracin A kiʻekiʻe ma ka hopena paepae hōʻike;e mālama ʻole i ka piko i ʻike ʻia ma ka Diluent.]
memo-Ua wehewehe ʻia ka ʻāpana o nā helu ma lalo nei ʻo ia ka ʻāpana o nā piko a pau koe ka paepae hōʻike.
maʻiʻo o ka bacitracin a-E helu i ka pākēneka o ka bacitracin A me ka hoʻohana ʻana i ke ʻano:
(rA / Huina nui) × 100
ʻo ka rA ka pane ʻāpana mai ka bacitracin A. ʻAʻole emi ka ʻike ma lalo o 40.0% o ka nui o ka nui.
maʻiʻo o ka bacitracin hana-E helu i ka pākēneka o ka bacitracin hana (bacitracin A, B1, B2, a me B3) me ka hoʻohana ʻana i ke ʻano:
(rA + rB1 + rB2 + rB3 / Ka huina nui)×100
i loko o ka rA, rB1, rB2, a me rB3 nā pane wahi mai bacitracin A, B1, B2, a me B3.ʻAʻole emi ka huina o ka bacitracin A, B1, B2, a me B3 ma mua o 70.0% o ka huina nui.
ka palena o nā peptides eluting mua - E helu i ka pakeneka o nā peaks a pau i hoʻoheheʻe ʻia ma mua o ka piko ma muli o ka bacitracin B1 me ka hoʻohana ʻana i ke ʻano:
(rPreB1 / Huina ʻāpana) ×100
i loko o ka rPreB1 ka huina o nā pane o nā piko a pau e hoʻoheheʻe ʻia ma mua o ka piko no ka bacitracin B1.ʻAʻole ʻoi aku ka palena o nā peptides eluting mua (ʻo ka poʻe eluting ma mua o ka piko ma muli o ka bacitracin B1) ʻaʻole ʻoi aku ma mua o 20.0%.
palena o bacitracin f- E helu i ka pākēneka o ka bacitracin F me ka hoʻohana ʻana i ke kumu:
100 × (rF / rA)
i loko o ka rF ka pane o ka bacitracin F mai ka hoʻonā Ho'āʻo;a ʻo rA ka pane o ka bacitracin A mai ka hoʻonā Hoʻo.ʻO ka palena o ka bacitracin F, kahi haumia i ʻike ʻia, ʻaʻole ia ma mua o 6.0%.
E hoʻomau me Bacitracin Zinc e like me ke kuhikuhi ʻana ma lalo o Antibiotics-Microbial Assays 81.
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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HS Code 2941909099
Lawe ʻia ʻo Bacitracin mai ka hopena moʻomeheu o ka lichen (Bacillus licheniformis) a he antibiotic polypeptide.ʻO ka pauka keʻokeʻo a i ʻole melemele māmā, ʻaʻala ʻole a ʻala iki paha, ʻono ʻawaʻawa, hygroscopic.Hiki ke hoʻoheheʻe ʻia i loko o ka wai a me ka ethanol, ʻaʻole paʻa, ʻaʻole hiki ke hoʻohana ʻia ka hopena wai ma ka lumi wela, paʻa ʻole i ka pH 9, a pono e hoʻopaʻa ʻia i loko o ka friji ma hope o ka hemo ʻana.Ua helu ʻia kēia huahana ma ke ʻano he hua maloʻo, a ʻo ka titer no ka milligram ʻaʻole e emi ma lalo o 55 bacitracin units.ʻO Bacitracin zinc ka bacitracin zinc paʻakai, ʻoi aku ka paʻa ma mua o ka bacitracin.Hoʻohana ʻia ia ma ke ʻano he meaʻai meaʻai a loaʻa iā ia nā hana o ka hoʻoulu ʻana i ka ulu a me ka ulu ʻana o nā holoholona a me nā moa, pale i nā maʻi ʻōpū, a me ka hoʻonui ʻana i ka uku hānai.Ua like ka dosage me ka bacitracin.Ua like ke ano o Bacitracin antibacterial me ka penicillin, nona ka hopena antibacterial ikaika i ka hua bacteria gram-positive a me ka hopena maopopo ole i ka bacteria gram-negative.No nā maʻi koʻikoʻi o Staphylococcus aureus kū i ka lāʻau.ʻAʻole komo ʻia ka lawelawe waha a hoʻohana ʻia no ka maʻi ʻōpū.Hoʻohana maikaʻi ʻia ka hoʻohana ʻana i waho no ka ʻili o ke kino, nā maʻi waha a me nā maka a me ka mastitis i hoʻokumu ʻia e ka maʻi bacteria koʻikoʻi.He hopena pōʻino ma nā puʻupaʻa.Ua hoʻohana ʻia ʻo Bacitracin zinc ma ke ʻano he mea hoʻohui lāʻau hānai.ʻAʻole ʻae ʻia ka lawelawe waha, no laila ke manaʻoʻiʻo ʻia ʻaʻohe pilikia koena lāʻau i nā holoholona a me nā huahana moa.ʻO kēia huahana he lāʻau antibiotic haiki-spectrum, nona ka hopena antibacterial ikaika i ka hapa nui o nā bacteria gram-positive.He mea maikaʻi nō hoʻi ia e kūʻē i nā spirochetes a me actinomycetes, akā ʻaʻole pono ia e kūʻē i ka bacteria gram-negative.Loaʻa ka hopena synergistic me nā ʻano lāʻau antibiotic e like me penicillin G, streptomycin, neomycin, polymyxin, etc. Hoʻohana nui ʻia kona paʻakai zinc ma ke ʻano he meaʻai meaʻai, nona nā hana o ka pale ʻana i ka maʻi ʻōpū, hoʻoikaika i ka ulu a hoʻomaikaʻi i ka uku hānai.Hiki i ka maʻi bacteria ke ulu mālie i ke kū'ē i kēia huahana, akā ʻaʻohe kūʻē kūʻē ma waena o kēia huahana a me nā lāʻau ʻē aʻe.He mea ʻawaʻawa kēia huahana a ʻaʻole hiki ke hoʻopaʻa ʻia.Hiki ke lawe waha ʻia no ka mālama ʻana i ka maʻi maʻi bacteria i nā holoholona a me ka maʻi dysentery Treponema i nā puaʻa.ʻO ka maʻi maʻi, hoʻohana pinepine ʻia i ka hui pū ʻana me nā lāʻau lapaʻau like ʻole e like me penicillin, streptomycin, neomycin, polymyxin B, etc. e hoʻonui i ka pono.
ʻO Bacitracin Zinc kahi paʻakikī i hana ʻia e ka bacitracin a me nā ion zinc.he antibiotic polypeptide a ʻo ia ka mea hoʻohana nui i ka meaʻai antibiotic i kēia manawa.ʻO ka nui o ka zinc he 2% ~ 12%.ʻO nā huahana synthetic he keʻokeʻo a melemele paha, me ka ʻala kūikawā, maʻalahi e hoʻoheheʻe i loko o nā mea alkaline nāwaliwali, a hiki ke hoʻoheheʻe ʻia i ka wai, methanol a me ka ethanol.He hopena antibacterial ikaika ko Bacitracin zinc e kū'ē i ka bacteria Gram-positive, a he mau waiwai antibacterial kekahi e kū'ē i kekahi mau bacteria Gram-negative.Hiki i ka hoʻohana ʻana i ka zinc bacitracin i loko o ka hānai puaʻa piha ke hoʻoikaika i ka ulu ulu, hoʻomaikaʻi i ka uku hānai, a pale i ka maʻi bacterial puaʻa a me nā maʻi hanu maʻi.ʻO ka manaʻo hoʻohui maʻamau he 10 ~ 100mg / kg, a ʻaʻole i hoʻomaikaʻi maikaʻi ʻia ka hopena ma mua o ka pae hoʻohui.ʻAʻole komo ʻo Bacitracin Zinc i loko o ka ʻōpū puaʻa, no laila ʻaʻohe pilikia i koe.He mea hoʻohui antibiotic palekana a hilinaʻi.He mea ʻona loa ka Bacitracin Zinc a ʻaʻole hiki ke komo maʻalahi e ka ʻōpū, no laila ʻaʻole hiki ke hoʻohana ʻia i mea lapaʻau no nā maʻi ʻōnaehana.
ʻO nā antibiotics Polypeptide he hopena antibacterial ikaika i ka bacteria gram-positive, a he hopena antibacterial hoʻi i kekahi mau hua bacteria gram-negative, spirochetes, actinomycetes a me ka penicillin-resistant staphylococci.ʻO ka hana antibacterial ka mea e pale ai i ka hoʻokumu ʻana o ka paia cell bacterial a hōʻino i ka membrane plasma cell bacterial.Hiki iā ia ke hoʻoikaika i ka ulu ʻana o nā microorganisms pono i loko o ka ʻōpū, hoʻonui i ka permeability o ka mucosa intestinal, a hoʻoikaika i ka absorption o nā meaʻai.Hoʻohana nui ʻia ia e hāpai i ka ulu ʻana o nā holoholona a me nā moa, pale a hoʻopaʻa i ka maʻi maʻi bacterial o nā holoholona a me ka moa a me ke koko maʻi i hoʻokumu ʻia e Treponema.ʻAʻole hiki ke komo i loko o ka Bacitracin zinc, a ʻo ka hapa nui o ia mea e hoʻokuʻu ʻia me nā feces i loko o 2 mau lā, no laila ʻaʻole maʻalahi ka noho ʻana i nā holoholona a me nā huahana moa;ʻAʻole hiki i ka bacteria ke kū'ē i ka bacitracin, a ʻaʻohe kūʻē kūʻē me nā lāʻau ʻē aʻe, A he hopena synergistic me ka penicillin, streptomycin, neomycin, aureomycin, polymyxin, a me nā mea ʻē aʻe.Hoʻopili ʻia kēia huahana me ke olaquindox, kitasamycin, virginiamycin, a me Enramycin.
Ma ke ʻano he meaʻai meaʻai, hoʻohana nui ʻia ia e hāpai i ka ulu ʻana o nā holoholona a me nā moa, pale i ka maʻi maʻi bacterial o nā holoholona a me nā moa a me ka maʻi maʻi koko i hoʻokumu ʻia e treponema.ʻAʻole hiki ke komo i loko o ka Bacitracin zinc, a ʻo ka hapa nui o ia mea e hoʻokuʻu ʻia me nā feces i loko o 2 mau lā, no laila ʻaʻole maʻalahi ka noho ʻana i nā holoholona a me nā huahana moa;ʻAʻole hiki i ka bacteria ke kū'ē i ka bacitracin, a ʻaʻohe kūʻē kūʻē me nā lāʻau ʻē aʻe, A he hopena synergistic me ka penicillin, streptomycin, neomycin, aureomycin, polymyxin, a me nā mea ʻē aʻe.Hoʻopili ʻia kēia huahana me ke olaquindox, kitasamycin, virginiamycin, a me Enramycin.
ʻO Bacitracin Zinc kahi antibiotic polypeptide, nona ka hopena bactericidal i ka maʻi bacteria gram-positive.ʻO kāna hana ka mea nui e kāohi i ka synthesis o ka pā bacterial o ka bacteria, a hiki ke hui pū me ka membrane cell o nā maʻi koʻikoʻi, e hōʻino i ka pono o ka membrane cell, a ke kumu i ka puka ʻana o nā mea nui i loko o ke kelepona.Kāohi pono i nā hua bacteria Gram-positive a me kekahi mau bacteria Gram-negative;Ua lohi ka nui o ka pale ʻana i ka maʻi bacteria i ka zinc bacitracin, a ʻaʻohe kūʻē keʻa me nā lāʻau ʻē aʻe.ʻO nā antibiotic polypeptide ke kāohi i ka dephosphorylation o lipid pyrophosphate, no laila ke kāohi nei i ka synthesis o nā paia cell bacteria.
