Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer
Hāʻawi Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Ka inoa: Bicalutamide
CAS: 90357-06-5
ʻO Bicalutamide i ka mālama ʻana i ka Advanced Prostate Cancer
API no ke kūlana kiʻekiʻe, hana kālepa
inoa | Bicalutamide |
Nā huaʻōlelo like | N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide |
Helu CAS | 90357-06-5 |
Helu CAT | RF-API76 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C18H14F4N2O4S |
Kaumaha Molecular | 430.37 |
Ka Mahana Waihona | 2-8 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a i ka pauka kristal keʻokeʻo |
ʻIkepili A | IR: Kūlike ke kiko o ka hāpana me ke kūlana kuhikuhi |
ʻIkepili B | HPLC: ʻO ka manawa paʻa o ka piko nui o ka hāpana hāpana e pili ana i ka hopena maʻamau |
ʻIkepili C | ʻIkepili Fluoride Organic |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i ka Acetone a me Tetrahydrofuran, hiki ke hoʻoheheʻe ʻia i ka Ethyl Acetate |
Lae hehee | 191.0~195.0 ℃ |
Waiwai (na KF) | ≤0.20% |
Maʻiʻo Fluoride | 15.9%~18.5% |
Nalo ma ka maloo | ≤0.50% |
Koena ma ka Ignition | ≤0.10% |
Nā Metala Kaumaha | ≤10ppm |
Nā mea hoʻoheheʻe koena | |
Tetrahydrofuran | ≤0.072% |
Toluene | ≤0.089% |
N-Hexane | ≤0.029% |
Acetone | ≤0.50% |
Ethyl Acetate | ≤0.50% |
Na mea pili | |
N,N'-Dimethyl Acetamide | ≤0.109% |
ʻO Bicalutamide Aminobenzonitrile | ≤0.10% |
ʻO Bicalutamide pili i ka hui A Isomer A | ≤0.10% |
ʻO Bicalutamide Pūnaʻi Pili A Isomer B | ≤0.10% |
Desfluoro Bicalutamide | ≤0.20% |
2-Fluoro Bicalutamide | ≤0.20% |
ʻO Deoxy Bicalutamide | ≤0.20% |
Bicalutamide Sulfide | ≤0.10% |
ʻO nā mea haumia ʻole i hōʻike ʻia | ≤0.10% |
Huina paumaele | ≤0.50% |
Ka nui o ka ʻāpana | 90%<10um;50%<5um |
Hoʻāʻo | 98.0%~102.0% (ma ke kumu maloʻo) |
Nā hoʻokolohua Microbiological | |
Huina Aerobic Viable | ≤500CFU/g |
Huna a me ka Molds | ≤50CFU/g |
Ola Pahu | 24 mahina |
Kūlana hoʻāʻo | ʻOihana Kūlana;USP Kūlana |
Hoʻohana | API, i ka mālama ʻana i ka Advanced Prostate Cancer |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Bicalutamide (CAS: 90357-06-5) he mea kū'ē i ka androgen non-steroidal, e hoʻokūkū ana i ka receptor androgen me ka androgen, poloka i ka lawe ʻana o ka androgen, a ke kāohi i ka hoʻopaʻa ʻana o nā androgens i ka mea i manaʻo ʻia.Hoʻopaʻa ia me ka androgen receptor i hoʻokumu i ka paʻakikī receptor, e komo i ka nucleus a hui pū me ka nucleoprotein, no laila ke keʻakeʻa nei i ka ulu ʻana o nā cell tumor.Hiki ke lilo i lāʻau lapaʻau mua no ka mālama ʻana i ka maʻi maʻi prostate kiʻekiʻe.Ua hoʻokuʻu ʻia ʻo Bicalutamide ma United Kingdom, kāna mākeke honua mua loa, no ka mālama ʻana i ka maʻi maʻi prostate holomua i hui pū ʻia me kahi LHRH analog a i ʻole castration surgical.ʻO kahi antiandrogen non-steroidal, peripherally selective antiandrogen, bicalutamide ke kāohi i ka hana o dihydrotestosterone a me ka testosterone ma nā wahi i hoʻopaʻa ʻia e ka hoʻokūkū hoʻokūkū i ka cytosolic androgen receptor.Ua hōʻike maikaʻi ʻia me ka loaʻa ʻole o nā hopena ʻaoʻao cardiovascular a me ka metabolic ma muli o ka pōmaikaʻi o ka nele i kekahi hana steroid.Ua hōʻike ʻia ka maikaʻi o ka bicalutamide ma ke ʻano he monotherapy.Ua hōʻike pū ʻia nā helu pane hoʻohiki i ka mālama ʻana i ka colorectal, ka umauma, ka pancreas a me nā maʻi maʻi ʻaʻa ʻole liʻiliʻi.