Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Maʻemaʻe ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate
Hoʻolako i nā mea kikowaena pili i ka Sitagliptin Phosphate Monohydrate:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Intermediate CAS 486460-21-3
Inoa Kimia | Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid |
Nā huaʻōlelo like | (R)-Sitagliptin N-Boc-Acid Impurity |
Helu CAS | 486460-00-8 |
Helu CAT | RF-PI1192 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
ʻĀpana Molekala | C15H18F3NO4 |
Kaumaha Molecular | 333.31 |
Lae hehee | 136.0~138.0 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
ʻIke ʻia e HPLC | ʻO ka manawa paʻa o ka laʻana e kūlike me ka maʻamau kuhikuhi |
Nalo ma ka maloo | ≤0.50% |
Lehu Sulphated | ≤0.50% |
Metala Kaumaha | <20ppm |
Isomer | ≤0.50% |
Na mea pili | |
haumia A | ≤0.50% |
ʻO nā mea haumia ʻē aʻe | ≤0.50% |
Huina paumaele | ≤0.50% |
Maemae | ≥99.5% (HPLC) |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Ka waena o Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai.
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ʻO Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) he mea koʻikoʻi ia no ka hoʻomākaukau ʻana i ka sitagliptin.ʻO Sitagliptinphosphate ka dipeptidase -IV (DPP-4) inhibitor mua i ʻae ʻia e FDA ma 2006. Hoʻohana ʻia ia no ka mālama ʻana i ka maʻi diabetes type II.Loaʻa ka hopena hypoglycemic inā hoʻohana wale ʻia a i hui pū ʻia me ka metformin a me ka pioglitazone, a palekana ke lawe ʻia, ʻae ʻia, me ka liʻiliʻi o nā hopena ʻino.I ʻAukake 2009, ua ʻae ʻia ka lāʻau lapaʻau e ka European Union ma ke ʻano he lāʻau lapaʻau mua no ka mālama ʻana i ka maʻi diabetes type 2.Ma hope o 2011, ua ʻae kekahi ma hope o nā ʻāina i ka hui pū ʻana o ka sitagliptin phosphate a me alpha glycosidase inhibitors a i ʻole insulin.ʻO Sitagliptin phosphate ka mea mua i ʻae ʻia e ka FDA i ka dipeptidyl peptidase-IV inhibitor e hoʻohana ʻia i ka mālama ʻana i ka maʻi diabetes type 2 ma kahi mamao, ma lalo o ka inoa kālepa Januvia.
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Sitagliptin CAS 486460-32-6 Maʻemaʻe >99.0% (HPLC...
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Sitagliptin Phosphate Monohydrate CAS 654671-77...
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2,4,5-Trifluorophenylacetic Acid CAS 209995-38-...
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Buty...
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Sitagliptin Triazole Hydrochloride CAS 762240-9...
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ʻO Sitagliptin Phosphate Monohydrate Intermediate ...