(Boc)2NH CAS 51779-32-9 Di-tert-Butyl Iminodicarboxylate Maʻemaʻe >99.0% (HPLC) Mea Hana Palekana
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui o Di-tert-Butyl Iminodicarboxylate ((Boc) 2NH) (CAS: 51779-32-9) me ke kūlana kiʻekiʻe.Hāʻawi ʻo Ruifu Chemical i kahi ʻano o nā reagents pale a me nā reagents hoʻohui.Hiki iā mākou ke hāʻawi i ka hāʻawi honua, ke kumukūʻai hoʻokūkū, nā mea liʻiliʻi a me ka nui i loaʻa.E kūʻai aku iā Di-tert-Butyl Iminodicarboxylate,Please contact: alvin@ruifuchem.com
Inoa Kimia | Di-tert-Butyl Iminodicarboxylate |
Nā huaʻōlelo like | (Boc)2NH;tert-Butyl Iminodicarboxylate;N-Boc-tert-Butylcarbamate;Iminodicarboxylic Acid Di-tert-Butyl Ester;ʻO Bis(tert-Butoxycarbonyl)amonia |
Kūlana Kūʻai | Loaʻa |
Helu CAS | 51779-32-9 |
ʻĀpana Molekala | C10H19NO4 |
Kaumaha Molekala | 217.27 g/mol |
Lae hehee | 114.0~120.0 ℃ |
ʻO ka mānoanoa | 1.037±0.06 g/cm3 |
Pilikino | Paʻi Lewa, Māmā |
Hiki i ka wai | ʻAʻole hiki ke hoʻonā i ka wai |
Ka hoʻoheheʻe | Chloroform, Methanol |
Waihona Temp. | Wahi anuanu a maloo (2~8 ℃) |
COA & MSDS | Loaʻa |
Māhele | Palekana Reagents |
Brand | Kemika Ruifu |
Nā mea | Nā Kūlana Nānā | Nā hualoaʻa |
Ka nana aku | Pauda Crystalline Keʻokeʻo | Hoʻokō |
Lae hehee | 114.0~120.0 ℃ | 118.8~119.3 ℃ |
Nalo ma ka maloo | <0.50% | 0.10% |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC) | 99.6% |
Infrared Spectrum | Kūlike i ka hoʻolālā | Hoʻokō |
NMR Spectrum | Kūlike i ka hoʻolālā | Hoʻokō |
Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō i nā kikoʻī i hāʻawi ʻia |
kolamu Chromatographic: SE-54 30m×0.25mm×0.5μm;
ʻIke: FID
Ka wela mua: 100 ℃
Ka manawa mua: 1min
Laki wela: 20 ℃ / min
Ka wela hope: 190 ℃
I ka hopena: 10 min
ʻO ke ana wela: 160 ℃
Ka wela o ka mea ike: 200 ℃
Māhele māhele: 50:1;
Laʻana nui: 0.2μl;
Mea hoʻoheheʻe: methanol
Ka hopena: Ua ʻoi aku ka maʻemaʻe ma mua o 99.0% ma ke ʻano hana maʻamau.
Pūʻolo:ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E kūʻai i loko o nā pahu i hoʻopaʻa ʻia ma kahi hale kūʻai maloʻo a maloʻo (2 ~ 8 ℃) mai nā mea like ʻole.E pale i ka malamalama a me ka wai.
Hoʻouna:Hāʻawi i ka honua ma FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Nā laʻana?Hāʻawi ka hapa nui o nā huahana i nā laʻana manuahi no ka loiloi maikaʻi, pono e uku ʻia ke kumukūʻai e nā mea kūʻai aku.
Hooia Hale Hana?Welina mai ka loiloi hale hana.E ʻoluʻolu e hoʻopaʻa manawa ma mua.
MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.
Manawa Hoʻouna? Inā i loko o ka waihona, ʻekolu lā hoʻouna ʻia.
Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.
Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.
Hoʻohui Kuʻuna?Hiki ke hāʻawi i nā lawelawe synthesis maʻamau e kūpono i kāu mau pono noiʻi.
Kūkākūkā uku?E hoʻouna mua ʻia ka invoice Proforma ma hope o ka hōʻoia ʻana o ke kauoha, hoʻopili ʻia kā mākou ʻike panakō.Uku e T/T (Telex Transfer), PayPal, Western Union, etc.
Nā hōʻailona pōʻino Xi - Hoʻonāukiuki
Nā Code Risk 36/37/38 - He mea hoʻonāukiuki i nā maka, ʻōnaehana hanu a me ka ʻili.
ʻO ka wehewehe palekana S26 - Inā pili me nā maka, holoi koke me ka wai nui a ʻimi i ka ʻōlelo aʻo kino.
S37/39 - E hoʻohana i nā mīkina lima kūpono a me ka pale maka/maka
WGK Kelemānia 3
HS Code 29241990
Nānā Hazard He mea hoʻonāukiuki
Di-tert-Butyl Iminodicarboxylate ((Boc)2NH) (CAS: 51779-32-9)
ʻO ka noi ʻana ʻo Di-tert-Butyl Iminodicarboxylate he lāʻau lapaʻau waena, hiki ke hoʻomākaukau ʻia e ka hopena hoʻokahi o ka formamide a me Boc2O.
Hoʻohana ʻia ka pūhui ma ke ʻano he reagent no ka hoʻomākaukau ʻana i nā amine mua mai nā alkyl halides.Ua hoʻolaha ʻia ma ke ʻano he ʻokoʻa i ka synthesis Gabriel no ka hoʻohuli like.Hiki ke hoʻomākaukau ʻia nā amine mai ka waiʻona ma ka hoʻohana ʻana i ka hopena Mitsunobu.I ka hoʻokō maʻamau, ua deprotonated ka reagent e hāʻawi i ka paʻakai potassium, ʻo ia ka N-alkylated.Hoʻopau ʻia nā pūʻulu pale Boc ma lalo o nā kūlana acidic.
ʻO Di-tert-Butyl Iminodicarboxylate kahi hui amine i hoʻohana ʻia e hoʻomākaukau i nā spirocycles conformationally constrained e like me CCR1 antagonists.
Hoʻomākaukau ʻia ka hopena o DMAP (0.61g, 5.0mmol) ma MeCN (15ml) e hoʻohui mālie ʻia i ka hopena o formamide (2.5g,56mmol) a me Boc2O (24).g, 110mol) i ka MeCN (15ml).Ma hope o ka hoʻoulu ʻana i ka lumi wela no 4h, ua hoʻomaha ʻia ka hopena melemele i 0 ° C, a ua hoʻohui mālie ʻia ka N,N-diethylenediamine (6.97g, 60mmol) ma 0 ℃.Ua hoʻouluʻia ka hopena o ka huiʻana i ka lumi wela no 12h a kānanaʻia ma o kahi silica pad;ua kānana ʻia ka hui ʻana ma ka lumi wela.A laila e hoʻoheheʻe ʻia ka solvent ma lalo o ke kaomi hoʻemi ʻia.Ua hoʻomaʻemaʻe ʻia ka huahana maʻemaʻe e ka silica gel chromatography a eluted me EtOAc/hexane (1:5) no ka loaʻa ʻana o ka huahana poʻo inoa, he paʻa keʻokeʻo (10.99g, 92%).