ʻO Brimonidine Tartrate CAS 70359-46-5 Hōʻike 99.0%~101.0%

ʻO Brimonidine Tartrate (CAS: 70359-46-5) kahi mea koho α2-receptor blocker, i hoʻomohala maikaʻi ʻia e ka US Company Allergan, kahi lāʻau lapaʻau maka.Hiki iā ia ke hoʻemi i ke kaomi intraocular (IOP).ʻO ka Brimonidine Tartrate ophthalmic solution saling i ka mākeke ʻo Brimonidine Tartrate form, he lāʻau hoʻohaʻahaʻa IOP maikaʻi no ka glaucoma hāmama ākea a me ka mālama hypertension ocular o nā maʻi, akā no nā pae argon laser IOP.ʻO ka Brimonidine Tartrate ophthalmic solution he ʻano hana ʻelua o ka hana ma o ka hoʻemi ʻana i ka hana hoʻokalakupua wai a me ka hoʻonui ʻana i ka papa puaʻa o ka wai scleral outflow therapeutic kumu.Ma hope o ka hāʻule ʻana i ka maka, wikiwiki ka hopena, a hiki ke piʻi i ka piko i ka wā e hoʻohana ai a hiki i 2h, a hiki i ka manawa kūpono ke mālama i ka 12h.Hiki i ke koko ke ʻike i nā ʻāpana o nā lāʻau lapaʻau.Loaʻa kēia huahana i ka metabolism mua i loko o ke akepaʻa, a hoʻokuʻu ʻia nā metabolites i loko o ka mimi e nā puʻupaʻa.ʻAʻole pili ka systemic absorption a me ka hāʻawi ʻana, a ʻaʻole pono ka poʻe ʻelemakule i ka hoʻoponopono ʻana.ʻO ka Brimonidine Tartrate ophthalmic solution i hoʻohālikelike ʻia me nā α-blockers ʻē aʻe, liʻiliʻi ka momona-soluble, ʻoiai ʻaʻole maʻalahi ke hele i loko o ka pale koko-lolo a ʻaʻole hoʻopuka i ka sedation, hypotension a me nā ʻano like ʻole o ka clonidine central adverse reactions.ʻO ka Brimonidine Tartrate Ophthalmic Solution he mea koho nui loa no nā mea loaʻa α2-adrenergic, a ʻoi aku ka nui o ka α2 / α1 ratio o ka pili o ka mea hoʻokipa ma mua o 1000 mau manawa.Hiki i ka hopena o nā mea loaʻa alpha 2 ke alakaʻi i ke kaomi intraocular haʻahaʻa.A ʻo ke kuleana o nā mea loaʻa alpha 1 hiki ke alakaʻi i ka ʻokiʻoki ʻana o ka vascular, ka hoʻihoʻi ʻana o ka lihilihi a i ʻole ka hōʻemi ʻana a me ka dilation o ka haumāna.ʻO ka hoʻohana lōʻihi ʻana o kēia huahana ʻaʻole ia e hoʻomaka i ka desensitization wikiwiki.Eia kekahi, ke hoʻohālikelike ʻia me nā β-blockers, hāʻule ka maka Brimonidine Tartrate no nā hopena cardiovascular liʻiliʻi, ʻaʻohe hopena i ka hana o ka māmā, no laila ua kūpono ia no nā poʻe maʻi kīnā β-blockers.Eia kekahi, ke hoʻohana wale ʻia ka β-blocker, ʻaʻole hiki ke hoʻokō i nā kumu therapeutic, a hiki iā ʻoe ke hoʻonui i ka FDA i ka manawa like.