Candesartan Cilexetil CAS 145040-37-5 Maʻemaʻe >99.0% (HPLC) API Kiʻi Hōʻike ʻia

Candesartan Cilexetil CAS 145040-37-5 Maʻemaʻe >99.0% (HPLC) API Hale Hana

ʻO ka wehewehe pōkole:

Inoa Kemika: Candesartan Cilexetil

CAS: 145040-37-5

Maʻemaʻe: >99.0% (HPLC)

ʻAno: Keʻokeʻo a i ʻole-White Crystalline Powder

He Antagonist Koho Angiotensin II Receptor

API Kūlana Kiʻekiʻe, Hana Hana Kūʻai

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Chemical Supply Candesartan Cilexetil Intermediate Me ka Maʻemaʻe Kiʻekiʻe
Candesartan Cilexetil CAS 145040-37-5
Candesartan CAS 139481-59-7
1-Chloroethyl Cyclohexyl Carbonate CAS 99464-83-2
Candesartan Cilexetil Intermediate Eethyl Ester C6 CAS 139481-41-7
Candesartan Cilexetil Intermediate CAS 139481-44-0
Trityl Candesartan Cilexetil CAS 170791-09-0

Na Waiwai Kemika:

Inoa Kimia	ʻO Candesartan Cilexetil
Nā huaʻōlelo like	TCV-116;1-((((Cyclohexyloxy)carbonyl)oxy)ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H -benzo[d]imidazole-7-Carboxylate
Helu CAS	145040-37-5
Helu CAT	RF-PI1891
Kūlana Kūʻai	Ma ka waihona, hoʻonui ʻia a hiki i nā tona
ʻĀpana Molekala	C33H34N6O6
Kaumaha Molecular	610.66
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Keʻokeʻo a i ka pauka kristal keʻokeʻo
ʻIke HPLC	ʻO ka manawa paʻa o ka piko nui ma ka chromatogram o ka hāpana e pili ana i kēlā i loko o ka chromatogram i loaʻa me ka maʻamau.
ʻIkepili IR	Ua like ka IR infrared absorption spectrum me ka Candesartan Cilexetil reference standard
ʻO ka māmā a me ke kala kala	ʻO ka hopena i loko o ka chloroform ma 5% he akaka a kala ʻole
Maʻemaʻe / Kaʻina Hanana	>99.0% (HPLC)
Lae hehee	155.0~160.0 ℃
Nalo ma ka maloo	<0.30%
Koena ma ka Ignition	<0.10%
Nā Metala Kaumaha	<10ppm
Arsenic (As)	<1ppm
Puka Lahui	90% <30 μm
Nā mea haumia kino	na HPLC
Ethyl Candesartan	<0.15%
ʻO Desethyl Candesartan	<0.15%
N2-Ethyl Candesartan Cilexei	<0.15%
ʻO ka haumia ʻike ʻole ʻia	<0.15%
Huina paumaele	<0.60%
ʻIke ʻia e ka Potentiometry	99.0~101.0% o C33H34N6O6, helu ʻia ma ka mea anhydrous
Organic Volatile haumia
Methano	<0.30%
Ethanol	<0.50%
ʻO Diethyl Etera	<0.50%
Aceton	<0.50%
Dichlorometana	<0.06%
ʻO Dimethylformamide	<0.088%
Microbiological Contarnination
Huina Aerobic Microbial Helu	<1000cfu/g
Molds & Yeasts	<100cfu/g
E.Coli	ʻAʻole
Salmonella	ʻAʻole
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	API;ʻAi Antihypertensive

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

ʻO Candesartan Cilexetil (TCV-116) (CAS: 145040-37-5) he angiotensin II receptor antagonist me IC50 o 0.26 nM, i hoʻohana ʻia i ka mālama ʻana i ka hypertension.ʻO Candesartan kahi angiotensin-receptor blocker (ARB) hiki ke hoʻohana wale ʻia a i ʻole me nā lāʻau ʻē aʻe e mālama i ka hypertension.Hāʻawi ʻia ia ma ka waha e like me ka prodrug, candesartan cilexetil, i hoʻololi koke ʻia i kāna metabolite ikaika, candesartan, i ka wā o ka absorption i ka ʻōpū o ka ʻōpū.Hoʻohaʻahaʻa ʻo Candesartan i ke koko ma o ka hoʻopaʻapaʻa ʻana i ka ʻōnaehana renin-angiotensin-aldosterone (RAAS);hoʻokūkū ʻo ia me ka angiotensin II no ka hoʻopaʻa ʻana i ka subtype angiotensin II receptor type-1 (AT1) a pale i ke kahe koko e hoʻonui i nā hopena o ka angiotensin II.ʻAʻole like me ka angiotensin-converting enzyme (ACE) inhibitors, ʻaʻole i loaʻa i nā ARB ka hopena ʻino o ka ʻu maloʻo.Hiki ke hoʻohana ʻia ʻo Candesartan no ka mālama ʻana i ka hypertension, ka hoʻokaʻawale systolic hypertension, left ventricular hypertrophy a me ka nephropathy diabetic.Hiki ke hoʻohana ʻia ma ke ʻano he mea hana ʻokoʻa no ka mālama ʻana i ka puʻuwai puʻuwai, systolic dysfunction, myocardial infarction a me ka maʻi coronary artery.