Capecitabine CAS 154361-50-9 Maʻemaʻe 98.0%~102.0% API Kūlana Kiʻekiʻe
Mea Kūʻai Kūʻai ʻo Capecitabine pili i waena:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
| Inoa Kimia | Capecitabine |
| Helu CAS | 154361-50-9 |
| Helu CAT | RF-API08 |
| Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
| ʻĀpana Molekala | C15H22FN3O6 |
| Kaumaha Molecular | 359.35 |
| Lae hehee | 110.0~121.0 ℃ |
| Kūlana Hoʻouna | Ma lalo o ka mahana wela |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Pauda keʻokeʻo |
| ʻIkepili | Pono ka la'ana o IR Spectrum me ka spectrum o ka ma'amau kuhikuhi |
| ʻIkepili | HPLC: Pono ka manawa paʻa o ka piko nui o ka hāpana hāpana e like me ka maʻamau kuhikuhi. |
| Maemae | 98.0% ~ 102.0% (ma ke kumu anhydrous a me ka solvent-free kumu) |
| ʻO ka hoʻololi ʻana | +96.0°~+100° |
| Māmā (KF) | ≤0.30% |
| Ke koena ma ka ʻā | ≤0.10% |
| Nā Metala Kaumaha | ≤20ppm |
| ʻO ka haumia pili A | ≤0.30% |
| ʻO ka haumia pili B | ≤0.30% |
| ʻO ka haumia pili C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Hoʻokahi ʻano haumia ʻole | ≤0.10% |
| Huina paumaele i hoakaka ole ia | ≤0.50% |
| Huina paumaele | ≤1.5% |
| Nā mea hoʻoheheʻe koena (GC) | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Toluene | ≤800ppm |
| Pyridine | ≤200ppm |
| Hexane | ≤290ppm |
| Huina Aerobic Microbial Helu | ≤200cfc/g |
| Ka helu ʻana i nā mea hu a me nā Molds | ≤50cfc/g |
| Kūlana hoʻāʻo | ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP) |
| Hoʻohana | ʻO ka maʻi maʻi maʻi maʻi metastatic |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Capecitabine (CAS: 154361-50-9) kahi ʻano hou o ka lāʻau pyrimidine fluorinated waha.Ua hoʻomohala ʻia ʻo Capecitabine e Roche Pharmaceuticals, a ʻo Xeloda kona inoa kālepa.Hiki i ka Capecitabine ke hoʻololi i loko o ka vivo i 5-FU, he lāʻau anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate e kuhikuhi ana i nā maʻi maʻi maʻi e keʻakeʻa i ka māhele cell a hoʻopau i ka RNA a me ka synthesis protein.Hoʻopili nui ʻia kona hopena i ke kiʻekiʻe o ka hōʻike enzyme TP i loko o ka ʻiʻo neoplastic a me ka DPD enzyme i ka ʻōlelo vivo.He kūpono ia e like me ka mālama hou ʻana no nā maʻi maʻi maʻi maʻi maʻi maʻi mua a metastatic paha i pane ʻole i ka paclitaxel a i ʻole anthracycline antibiotic.Ma ke ʻano he lāʻau anticancer, hoʻohana nui ʻia ia e mālama i ka maʻi maʻi umauma mua a metastatic paha, a me ka mālama ʻana no ka maʻi maʻi ʻaʻai liʻiliʻi liʻiliʻi, ka maʻi ʻaʻai pancreatic, ka maʻi maʻi ʻaʻai, ka maʻi ʻaʻai rectal, ka maʻi maʻi ʻāʻī, ka maʻi ʻōpū, a me nā maʻi maʻi ʻē aʻe. .
