3-[1-(Dimethylamino)ethyl]phenol CAS 105601-04-5 Rivastigmine Tartrate Ma'ema'e Waena >98.0% (HPLC)

ʻO 3-[1-(Dimethylamino)ethyl]phenol (CAS: 105601-04-5) kahi mea waena o Rivastigmine Tartrate (CAS: 129101-54-8).ʻO Rivastigmine Tartrate ka rivastigmine maʻi maʻi o Alzheimer, ʻo rivastigmine ka physostigmine derivative e Novartis no ka manawa mua i hoʻomohala maikaʻi i ka inoa kalepa ʻo Exelon, kahi mole me ka hale karbamate ma laila, he ʻano amino acid o ka koho cerebral cholinesterase inhibitor, hiki ke kāohi i ka acetylcholinesterase a butyrylcholinesterase, cholinergic neurons ma ka hoʻopaneʻe ʻana i ka hoʻokuʻu ʻana o ka acetylcholine degradation a me ka ikehu e hoʻoikaika ana i ka conduction nerve cholinergic, hiki ke hoʻomaikaʻi i nā pilikia hana cognitive i hoʻopili ʻia e ka cholinergic, a laila e hoʻomaikaʻi ai i ka hana cognitive o nā maʻi maʻi o Alzheimer.He nāwaliwali ka hoʻopaʻa ʻana o ka protein plasma Rivastigmine, maʻalahi ma o ka pale koko-lolo, kahi kiʻekiʻe o ka koho lolo.ʻAʻole wale ia e hana maʻalahi i ka cerebral cortex a me ka hippocampus i maʻalahi loa, akā makemake pū kekahi i ka subtype dominant o AChE i loko o ka lolo, e hoʻemi ana i ka maikaʻi o nā hopena ʻaoʻao cholinergic peripheral.ʻO ka Rivastigmine i loko o vivo ka hapalua o ke ola he pōkole a lōʻihi ka lōʻihi o ka hana.ʻAʻole like me ka tacrine, ʻoi aku ka ikaika o kēia huahana i ka hippocampus a me ka cortex o ka hopena inhibitory enzyme G1.Ke kauka no ka mālama ʻana i ke ʻano dementia ʻano haʻahaʻa a me ka haʻahaʻa, a i ʻole ka maʻi Alzheimer hiki ke hoʻopaʻapaʻa ʻia ʻo ia ka maʻi o Alzheimer.