1-(3-Methoxypropyl)-4-Piperidinamine CAS 179474-79-4 Prucalopride Succinate Maʻemaʻe Kūwaena >98.0% (GC)

ʻO kēia huahana he 1-(3-Methoxypropyl) -4-Piperidinamine.Loaʻa i ka C9H20N2O ʻaʻole e emi iho ma mua o 98.0%, helu ʻia ma ke kumu anhydrous.
[Pono: ʻAʻole waihoʻoluʻu kēia huahana i ka wai melemele māmā.
E lawe i ka wai kūpono o kēia huahana, e hoʻohui i ka solvent (methanol), e hoʻoheheʻe iā ia, e hoʻoholo e like me ke ʻano o ka hoʻoholo ʻana i ka wai (Appendix Ⅷ M, ke ʻano mua A), e hoʻohana i nā kulu hoʻāʻo a Fisher e hoʻoholo a hiki i ka hoʻololi ʻana o ka hopena mai ka melemele māmā. i ʻulaʻula ʻulaʻula e hōʻike ana i ka helu hope, a hana i kahi hoʻāʻo ʻē aʻe.E helu e like me kēia ʻano: ʻaʻole pono ka nui o ka wai ma mua o 1.0%.
ʻO ka ʻoluʻolu (%) = (AB) F/W×100%
Aia, ʻo A ka nui o ka wai a Fisher i hoʻopau ʻia e ka huahana hoʻāʻo (ml);
ʻO B ka nui o ka wai hoʻāʻo a Fisher i hoʻopau ʻia e kahi hakahaka, ml;
ʻO F ke kaumaha o ka hopena hoʻāʻo a Fisher e like me ka wai no 1ml, mg;
ʻO W ke kaumaha o ka huahana hoʻāʻo, mg
ʻO ka haumia hoʻokahi
E like me nā kūlana ʻike a me nā ʻano ma lalo o [ka hoʻoholo ʻana i ka ʻike], ua hoʻopaʻa ʻia ka chromatogram a ʻo ka manawa paʻa mai ka piko nui he 3 mau manawa.Inā loaʻa kahi kiʻekiʻe haumia i ka hopena hoʻāʻo, ʻaʻole ʻoi aku ka haumia hoʻokahi ma mua o 0.5% a ʻaʻole ʻoi aku ka nui o nā haumia a pau ma mua o 2.0% e like me ke ʻano o ke ʻano maʻamau.
[Ka Hoʻoholo Maikaʻi] E like me ke ʻano o ka hoʻoholo ʻana i ke koena solvent (Hoʻohui Ⅷ P)
(6%) cyanopropyl phenyl - (94%) dimethylpolysiloxane (a i ʻole polarity like) e like me ke kolamu capillary wai paʻa;
Ua hoʻohana ʻia ke ʻano hoʻomehana i hoʻolālā ʻia o ka ʻōnaehana sampling headspace column capillary me nā kūlana chromatographic gas.ʻO ka mahana mua he 100 ℃ no 5min, a ua hoʻokiʻekiʻe ʻia ka mahana ma 15 ℃ i kēlā me kēia minuke i 250 ℃ no 4min.He 250 ℃ ka wela inlet, a he 280 ℃ ka mahana detector.ʻO 4ml / min ka kahe kahe.ʻO ka ratio shunt he 8: 1.
Ma kahi o 0.6g o kēia huahana i lawe ʻia, kaupaona pono ʻia, waiho ʻia i loko o kahi ʻōmole 10ml, hoʻoheheʻe ʻia me ka methanol a hoʻoheheʻe ʻia i ka pālākiō, e like me ka hopena huahana hoʻāʻo.Ua hoʻokomo ʻia ka hāpana hāpana me 1μl no ka liʻiliʻi ʻelua mau manawa.Hoʻoholo ʻia ka ʻāpana kiʻekiʻe o ka piko e ana ʻia.ʻAʻole i emi iho ka maʻemaʻe kiʻekiʻe ma mua o 98.0% e like me ke ʻano maʻamau maʻamau.