3-Chloro-4-(3-Fluorobenzyloxy)aniline CAS 202197-26-0 Lapatinib Ma'ema'e Waena >98.0% (HPLC)
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui o 3-Chloro-4-(3-Fluorobenzyloxy) aniline (CAS: 202197-26-0) me ke kūlana kiʻekiʻe.Hiki iā Ruifu Chemical ke hāʻawi aku i ka honua holoʻokoʻa, ke kumukūʻai hoʻokūkū, ka lawelawe maikaʻi loa, ka liʻiliʻi a me ka nui nui i loaʻa.Kūʻai i nā Lapatinib Intermediates,Please contact: alvin@ruifuchem.com
Inoa Kimia | 3-Chloro-4-(3-Fluorobenzyloxy)aniline |
Nā huaʻōlelo like | 3-Chloro-4-[(3-Fluorophenyl)methoxy]aniline;4-(3-Fluorobenzyloxy)-3-Chlorobenzenamine;ʻO Lapatinib Intermediate B |
Kūlana Kūʻai | Ma ke Kahua, Hana Hana Kūʻai |
Helu CAS | 202197-26-0 |
ʻĀpana Molekala | C13H11ClFNO |
Kaumaha Molecular | 251.69 g/mol |
Lae hehee | 78.0 a 82.0 ℃ |
ʻO ka mānoanoa | 1.306±0.06 g/cm3 |
COA & MSDS | Loaʻa |
Laʻana | Loaʻa |
Ke kumu | Shanghai, Kina |
Brand | Kemika Ruifu |
Nā mea | Nā Kūlana Nānā | Nā hualoaʻa |
Ka nana aku | Palaka a ʻEleʻele Pauda | Hoʻokō |
Lae hehee | 78.0 a 82.0 ℃ | 80.7 ℃ |
Nalo ma ka maloo | <1.00% | Hoʻokō |
Koena ma ka Ignition | <0.50% | Hoʻokō |
Nā mea haumia pili e HPLC | <2.00% | 0.64% |
Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) | 99.36% |
1H NMR Spectrum | Kūlike me ka Hoʻolālā | Hoʻokō |
Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō me nā kikoʻī i hāʻawi ʻia | |
Palapala noi | Ka waena o Lapatinib / Lapatinib Ditosylate Monohydrate |
Pūʻolo:ʻO ka ʻōmole Fluorinated, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E hoʻopaʻa paʻa i ka pahu a mālama i loko o kahi hale kūʻai maloʻo a me ka makani maikaʻi mai nā mea like ʻole.E pale i ka malamalama a me ka wai.
Hoʻouna:Hāʻawi i ka honua ma ka lewa, e FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 mau makahiki ʻike?Loaʻa iā mākou ma mua o 15 mau makahiki o ka ʻike i ka hana ʻana a me ka hoʻokuʻu ʻana aku i kahi ākea ākea o nā intermediates pharmaceutical kiʻekiʻe a i ʻole nā kemika maikaʻi.
Mākeke Nui?E kūʻai aku i ka mākeke kūloko, ʻAmelika ʻĀkau, ʻEulopa, India, Korea, Iapana, Australia, etc.
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MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.
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Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.
Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.
Hoʻohui Kuʻuna?Hiki ke hāʻawi i nā lawelawe synthesis maʻamau e kūpono i kāu mau pono noiʻi.
Kūkākūkā uku?E hoʻouna mua ʻia ka invoice Proforma ma hope o ka hōʻoia ʻana o ke kauoha, hoʻopili ʻia kā mākou ʻike panakō.Uku e T/T (Telex Transfer), PayPal, Western Union, etc.
UN ID 3077
HS Code 2921420090
Papa Hazard 9
Hui Pūʻulu III
ʻO 3-Chloro-4-(3-Fluorobenzyloxy)aniline (CAS: 202197-26-0) he mea waena i ka synthesis o Lapatinib / Lapatinib Ditosylate Monohydrate.
ʻO Lapatinib kahi lāʻau lapaʻau e nānā ana i ka maʻi kanesa o ka umauma i hoʻomohala ʻia e British GlaxoSmithKline Co. ʻO nā mea loaʻa ErbB kanaka no ka ʻohana receptor type I tyrosine kinase (TK), me ErbB1 (EGFR), ErbB2 (HER2), ErbB3 (HER3), a me ErbB4 (HER4) .ʻO nā mea hoʻokipa ErbB-1 (EGFR) a me ErbB-2 (HER-2) i hoʻohālikelike pinepine ʻia a hoʻololi ʻia paha i nā maʻi maʻi maʻi.Ua ʻike ʻia ʻo ke kanaka epidermal growth factor receptor 2 (ErbB-2, HER-2) he oncogene kanaka pili loa me ka maʻi maʻi umauma.ʻO kāna ʻōlelo kiʻekiʻe i ka maʻi maʻi umauma e wānana pinepine i ka metastasis lymph node a me ka ʻokoʻa ʻana o ka maʻi tumora, me ka maikaʻi ʻole o ka prognosis.ʻO HER-2 kekahi o nā molekele i hoʻopaʻa ʻia no ka maʻi maʻi maʻi maʻi.Hiki i ka Lapatinib ke hana like ma ka Her-1 Her-2.ʻOi aku ka nui o nā hopena olaola o kēia ʻano hana e pale ai i ka hoʻonui ʻana a me ka ulu ʻana o nā cell tumor ma mua o ka hana wale ʻana i hoʻokahi pahuhopu.Hoʻohana ʻia ka hui pū ʻana o Lapatinib me Capecitabine e mālama i nā maʻi me ka maʻi maʻi maʻi a i ʻole metastatic o ka umauma me ka overexpression o ka epidermal receptor2 kanaka, ua mālama ʻia me nā anthracyclines, paclitaxel, a me trastuzumab.Ua hōʻike ʻia nā hoʻokolohua lapaʻau e mālama pono ʻo Lapatinib i nā maʻi maʻi maʻi maʻi ʻano HER2 me ka pale ʻana iā Herceptin.