Lapatinib Intermediate CAS 231278-84-5 Maʻemaʻe >98.0% (HPLC)
Inoa Kimia | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Nā huaʻōlelo like | Lapatinib Intermediate 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl]-2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Helu CAS | 231278-84-5 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā tona |
ʻĀpana Molekala | C26H17ClFN3O3 |
Kaumaha Molecular | 473.90 |
Lae hehee | 225.0 a 235.0 ℃ |
ʻO ka mānoanoa | 1.407±0.06 g/cm3 |
Hōʻike Hōʻike | 1.694 |
COA & MSDS | Loaʻa |
Ke kumu | Shanghai, Kina |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Melemele ʻeleʻele i ka pauda paʻa melemele |
Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) |
Lae hehee | 225.0~235.0 ℃ |
Nalo ma ka maloo | <1.00% |
Koena ma ka Ignition | <0.50% |
Huina paumaele | <2.00% |
Nā Metala Kaumaha (e like me Pb) | <20ppm |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Waena o API (CAS 388082-77-7) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
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5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) mea waena o API (CAS 388082-77-7 ).(CAS 388082-77-7) he lāʻau lapaʻau e huli ana i ka maʻi maʻi umauma i hoʻomohala ʻia e British GlaxoSmithKline Co. ʻO ia ka tyrosine kinase inhibitor e hiki ke pale pono i ka hana tyrosine kinase o ke kanaka epidermal growth factor receptors 1 a me 2 (ErbB1, ErbB2).Hiki iā ia ke hana kūikawā ma nā ʻano like ʻole, e hōʻoiaʻiʻo ʻaʻole hiki i nā maʻi maʻi maʻi umauma ke loaʻa nā hōʻailona ulu.Kāohi ia i nā pūnaewele EGFR (ErbB-1) intracellular a me HER2 (ErbB-2) ATP, e pale ana i ka phosphorylation cell tumor a me ka hoʻāla ʻana, e kāohi ana i nā hōʻailona hoʻoponopono ma o ka homogeneity a me ka heterogeneity o EGFR (ErbB-1) a me HER2 (ErbB-1) dimerization.
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