CAS 361442-04-8 Maʻemaʻe >99.0% (HPLC) API

ʻO ka wehewehe pōkole:

Nā huaʻōlelo like: BMS-477118;ʻO Onglyza

CAS: 361442-04-8

Maʻemaʻe: >99.0% (HPLC)

Nānā: Pada Keʻokeʻo

API, Mea Kiʻekiʻe, Hana Kalepa

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Chemical Supply pili i waena
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Na Waiwai Kemika:

Nā huaʻōlelo like	BMS-477118;Onglyza;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-Hydroxy-1-Adamantyl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-Carbonitrile;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-Hydroxytricyclo [3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane -3-Carbonitrile
Helu CAS	361442-04-8
Helu CAT	RF-PI1991
Kūlana Kūʻai	Ma ka waihona, hoʻonui ʻia a hiki i nā tona
ʻĀpana Molekala	C18H25N3O2
Kaumaha Molecular	315.41
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Pauda keʻokeʻo
ʻala	ʻano ʻano
ʻike ʻike	A: IR B: Manawa Paʻa HPLC
Maʻemaʻe / Kaʻina Hanana	>99.0% (HPLC)
Malamalama o ka Wai	Alohilohi, kala ʻole, ʻaʻohe mea i hoʻopaʻa ʻia
Anana Anaina	100% Holo i ka 80 Mesh
Lae hehee	202.0~212.0 ℃
Nalo ma ka maloo	<0.50%
Lehu Sulphated	<0.20%
Hoʻololi kikoʻī	+174.0°~+186.0°
Hoʻokahi haumia	<0.50%
Huina paumaele	<1.00%
Nā Metala Kaumaha	<10ppm
Arsenic (As)	<2.0ppm
Ke kēpau (Pb)	<1.0ppm
Cadmium (Cd)	<1.0ppm
Nā mea hoʻoheheʻe koena	<100ppm
Pesticide koena	ʻinoʻino
Microbiology
Huina Papa	<1000cfu/g
Huna & Mold	<100cfu/g
E. Coli	ʻinoʻino
S. Aureus	ʻinoʻino
Salmonella	ʻinoʻino
Ola Pahu	24 mau mahina mai ka lā hana inā mālama pono ʻia
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	API;ʻO ka maʻi maʻi diabetes type 2

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

(BMS-477118) (CAS: 361442-04-8) he mea ikaika, koho, hoʻololi, hoʻokūkū a me ka waha i ka dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) mea hoʻonā.Loaʻa iā BMS-477118 ka peotential no ka noiʻi maʻi diabetes type 2.BMS-477118he lāʻau maʻi diabetes type 2 hiki ke hoʻoulu i ka pancreas e hana hou aku i ka insulin ma hope o ka ʻai ʻana.Ua hōʻea ʻia e ka hui pū ʻana o AstraZeneca a me Bristol-Myers Squibb Company a nona ka DPP-IV inhibitor.BMS-477118pāʻani i ka hana ma o ka pale ʻana i ka hoʻohaʻahaʻa GLP-l.ʻO GLP-I nā hormones i hana maoli ʻia i loko o ka ʻōpū ma hope o ka ʻai ʻana i ka meaʻai.Hiki iā ia ke hoʻoponopono i ka huna ʻana o ka insulin a hoʻoikaika i ka hoʻohana ʻana i ka glucose i loko o nā ʻiʻo peripheral.Hiki i ka lāʻau lapaʻau hoʻokahi o BMS-477118 ke hoʻomaikaʻi i ka mana glucose koko a me ka lāʻau lapaʻau hui pū ʻia o BMS-477118 me Metformin, Sulfonylurea a me Thiazolidinediones hiki ke hoʻonui i ka hopena curative.Ke alakaʻi nei ia i ka haʻahaʻa haʻahaʻa o ka hypoglycemia a me kāna mau hopena ʻino e like me ka placebo, e hōʻike ana i ka hoʻomanawanui ʻoi aku ka maikaʻi.Ma Iulai 31, 2009, BMS-477118 nā papa (Onglyza), he lāʻau lapaʻau hou o ka maʻi diabetes type 2, i noiʻi pū ʻia a hoʻomohala ʻia ʻo AstraZeneca a me Bristol-Myers Squibb i ʻae ʻia e ka US FDA.Hiki ke lawe ʻia i hoʻokahi lā no ka mālama ʻana i ka maʻi diabetes type 2 i hui pū ʻia me ka mālama ʻana i ka meaʻai a me ka hoʻoikaika kino.