Apixaban Intermediate CAS 545445-44-1 Maʻemaʻe >98.0% (HPLC)
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui o 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445 -44-1) me ke kūlana kiʻekiʻe, waena o Apixaban (CAS: 503612-47-3).Hiki iā Ruifu Chemical ke hāʻawi aku i ka honua holoʻokoʻa, ke kumukūʻai hoʻokūkū, ka lawelawe maikaʻi loa, ka liʻiliʻi a me ka nui nui i loaʻa.Kūʻai i nā Apixaban Intermediates,Please contact: alvin@ruifuchem.com
| Inoa Kimia | 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one |
| Nā huaʻōlelo like | Apixaban Intermediate 1;5,6-Dihydro-3-(4-Morpholinyl)-1-[4-(2-Oxo-1-Piperidinyl)phenyl]-2(1H)-Pyridinone;5-Morpholin-4-yl-1-[4-(2-Oxopiperidin-1-yl)phenyl]-2,3-Dihydropyridin-6-one;ʻO Apixaban haumia A |
| Kūlana Kūʻai | Ma ke Kahua, Hana Hana Kūʻai |
| Helu CAS | 545445-44-1 |
| ʻĀpana Molekala | C20H25N3O3 |
| Kaumaha Molecular | 355.43 g/mol |
| Lae hehee | >199℃(Dek.) |
| ʻO ka mānoanoa | 1.267 g/mL |
| COA & MSDS | Loaʻa |
| Ke kumu | Shanghai, Kina |
| Māhele | Kūwaena o Apixaban (CAS: 503612-47-3) |
| Brand | Kemika Ruifu |
| Nā mea | Nā kikoʻī | Nā hualoaʻa |
| Ka nana aku | Pauda Melemele Māmā | Pauda Melemele Māmā |
| Nalo ma ka maloo | <0.50% | 0.16% |
| Koena ma ka Ignition | <0.20% | 0.07% |
| Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC Area) | 99.12% |
| ʻO kēlā me kēia haumia kanaka | <0.50% | <0.50% |
| Huina paumaele | <2.00% | 0.88% |
| 1H NMR Spectrum | Kūlike me ka Hoʻolālā | Kūlike |
| LC-MS no ka ʻike | Kūlike | Kūlike |
| Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō me nā kikoʻī i hāʻawi ʻia | |
| Palapala noi | Kūwaena o Apixaban (CAS: 503612-47-3) | |
Pūʻolo:ʻO ka ʻōmole Fluorinated, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
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Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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ʻO 3-Morpholino-1-(4-(2-Oxopiperidin-1-yl)phenyl)-5,6-Dihydropyridin-2(1H)-one (CAS: 545445-44-1) he mea waena o Apixaban (CAS: 503612-47-3).
ʻO Apixaban kahi ʻano hou o ka waha Xa factor inhibitor i hoʻomohala pū ʻia e Bristol-Myers Squibb a me Pfizer.ʻO ka inoa kālepa ʻo Eratol, he ʻano hou o ka anticoagulant waha.Ma ke kāohi ʻana i kahi mea coagulation koʻikoʻi Xa, hiki iā Apixaban ke pale i ka hana thrombin a me ka thrombosis.Ma ʻApelila 26, 2007, hui pū ʻo Bristol-Myers Squibb me Pfizer e hoʻolaha i ka hui pū ʻana i ka hoʻomohala ʻana i kahi anticoagulant waha hou ʻo Apixaban nona Bristol-Myers Squibb ma ke ʻano he mea hou i Warfarin.I ka Mei 2011, ʻo Apixaban ka mea mua i ʻae i ka pale ʻana i ka thrombosis venous i nā poʻe maʻi makua e hana ana i ka ʻoki ʻoki ʻāʻī a i ʻole ke kuli ma 27 mau ʻāina EU, Iceland a me Norewai.Ma ka lā 20 o Nowemapa, 2012, ua ʻae ke Komisina ʻEulopa iā Ererto (Apixaban) no ka pale ʻana i ka hahau a me ka systemic embolism i nā poʻe maʻi makua me ka non-valvular atrial fibrillation (NVAF) me hoʻokahi a ʻoi aku paha nā mea pilikia.Ma hope mai, ua ʻae ka Canadian Food and Drug Administration, Iapana, a me ka US FDA iā Ererto (Apixaban) no ka pale ʻana i ka hahau a me ka systemic embolism i nā poʻe maʻi maʻi me ka non-valvular atrial fibrillation (NVAF) me hoʻokahi a ʻoi aku paha nā mea pilikia.Ma ʻApelila 12, 2013, ua hoʻolaha ʻia ka lāʻau anticoagulant hou ʻo Eloto (ELIQUIS) (Apixaban) i hui pū ʻia e Bristol-Myers Squibb a me Pfizer e hoʻopaʻa inoa ʻia ma Kina.
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