Trelagliptin Succinate Intermediate CAS 865759-24-6 Maʻemaʻe >98.0% (HPLC)

ʻO ka wehewehe pōkole:

ʻO Trelagliptin Succinate Intermediate-int D

CAS: 865759-24-6

Maʻemaʻe: >98.0% (HPLC)

ʻIke: Keʻokeʻo-Keʻokeʻo a i ka Crystal Melemele Māmā

Intermediate o Trelagliptin Succinate (CAS: 1029877-94-8) no ka mālama ʻana i ka maʻi maʻi type 2

Hoʻokaʻaʻike: Kauka Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

Mea Kūʻai Kūʻai ʻo Trelagliptin Succinate E pili ana i waena:
6-Chloro-3-Methyluracil CAS 4318-56-3
2-Cyano-5-Flurobenzyl Bromide CAS 421552-12-7
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
Trelagliptin Succinate Intermediate-int D CAS 865759-24-6
Trelagliptin Succinate CAS 1029877-94-8
Please contact: alvin@ruifuchem.com

Na Waiwai Kemika:

Inoa Kimia	ʻO Trelagliptin Succinate Intermediate-int D
Nā huaʻōlelo like	2-((6-Chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile;2-[(6-Chloro-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl)methyl]-4-fluorobenzonitrile
haumia	Trelagliptin haumia 17
Kūlana Kūʻai	Ma ka Waihona, Ka Uuna Kūʻai
Helu CAS	865759-24-6
ʻĀpana Molekala	C13H9ClFN3O2
Kaumaha Molecular	293.68 g/mol
ʻO ka mānoanoa	1.49±0.10 g/cm3
Waihona Temp.	Wahi Puanu a maloo
COA & MSDS	Loaʻa
Brand	Kemika Ruifu

Nā kikoʻī:

Nā mea	Nā Kūlana Nānā	Nā hualoaʻa
Ka nana aku	Keʻokeʻo-keʻokeʻo a i ka Crystal Melemele Māmā	Kūlike
ʻIkepili
HPLC	ʻO ka manawa paʻa o ka laʻana hōʻike kiʻekiʻe nui e like me ka maʻamau kuhikuhi	Kūlike
IR - Spectrum Infrared	IR Absorption spectra o ka laʻana a me ka maʻamau i concordant	Kūlike
Nānā
Nalo ma ka maloo	<0.50%	0.3%
Huina paumaele	<2.00%	Kūlike
Maʻemaʻe / Kaʻina Hanana	>98.0% (HPLC)	99.1%
Ka hopena	Ua hoʻāʻo ʻia ka huahana a hoʻokō i nā kikoʻī

Pūʻolo/Paʻa/Hoʻouna:

Pūʻolo:ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E kūʻai i loko o nā pahu i hoʻopaʻa ʻia ma kahi hale kūʻai maloʻo a maloʻo maikaʻi mai nā mea like ʻole.E pale i ka malamalama a me ka wai.E pale i ka malamalama;Paʻa ea.
Hoʻouna:Hāʻawi i ka honua ma FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.

Pono:

ʻO ka mana kūpono: lawa nā lako a me nā ʻenehana

ʻOihana Hoʻonaʻauao: Hoʻokahi lawelawe kūʻai kūʻai

Puke OEM: Loaʻa ka pūʻolo maʻamau a me ka lepili

Hoʻouna wikiwiki: Inā i loko o ke kumukūʻai, ʻekolu lā hoʻouna i hōʻoia ʻia

Hoʻolako Paʻa: E mālama i ka waiwai kūpono

Kākoʻo ʻenehana: Loaʻa ka hopena ʻenehana

Hana Hana Hana Kuʻuna: Mai ka grama a hiki i ke kilo

Kūlana Kiʻekiʻe: Hoʻokumu i kahi ʻōnaehana hōʻoia maikaʻi piha

FAQ:

Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

15 mau makahiki ʻike?Loaʻa iā mākou ma mua o 15 mau makahiki o ka ʻike i ka hana ʻana a me ka hoʻokuʻu ʻana aku i kahi ākea ākea o nā intermediates pharmaceutical kiʻekiʻe a i ʻole nā kemika maikaʻi.

Mākeke Nui?E kūʻai aku i ka mākeke kūloko, ʻAmelika ʻĀkau, ʻEulopa, India, Korea, Iapana, Australia, etc.

Nā pono?ʻO ke kūlana kiʻekiʻe, ke kumukūʻai kūpono, nā lawelawe ʻoihana a me ke kākoʻo ʻenehana, ka lawe wikiwiki ʻana.

ʻAno maikaʻiHōʻoiaʻiʻo?Pūnaehana hoʻomalu maikaʻi koʻikoʻi.ʻO nā lako ʻoihana no ka nānā ʻana ʻo NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.

Nā laʻana?Hāʻawi ka hapa nui o nā huahana i nā laʻana manuahi no ka loiloi maikaʻi, pono e uku ʻia ke kumukūʻai e nā mea kūʻai aku.

Hooia Hale Hana?Welina mai ka loiloi hale hana.E ʻoluʻolu e hoʻopaʻa manawa ma mua.

MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.

Manawa Hoʻouna? Inā i loko o ka waihona, ʻekolu lā hoʻouna ʻia.

Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.

Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.

Hoʻohui Kuʻuna?Hiki ke hāʻawi i nā lawelawe synthesis maʻamau e kūpono i kāu mau pono noiʻi.

Kūkākūkā uku?E hoʻouna mua ʻia ka invoice Proforma ma hope o ka hōʻoia ʻana o ke kauoha, hoʻopili ʻia kā mākou ʻike panakō.Uku e T/T (Telex Transfer), PayPal, Western Union, etc.

Noi:

Hoʻohana ʻia ʻo 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile (CAS: 865759-24-6) waena o Trelagliptin Succinate (CAS: 1029877-94-8).ʻO Trelagliptin Succinate, i hoʻomohala ʻia e Takeda, Iapana, i hoʻokuʻu ʻia ma Malaki 2015, ma lalo o ka inoa kālepa Zafatek, hoʻohana ʻia e mālama i ka maʻi maʻi type 2.ʻO Trelagliptin kahi mea hoʻopaneʻe ultra-long-acting dipeptidyl peptidase IV (DPP-4) ma ke koho a hoʻomau mau ʻana i ka DPP-4 e kāohi i ke kiʻekiʻe o ke kō koko.ʻO Trelagliptin ka lāʻau lapaʻau hypoglycemic wiki mua ma ka mākeke, a pono e lawe ʻia nā mea like DPP-4 ma ka mākeke i hoʻokahi manawa i ka lā.ʻO ka pōmaikaʻi o ka lāʻau Zafatek e hāʻawi i nā koho lapaʻau maʻalahi no nā maʻi maʻi maʻi.Manaʻo ia e hoʻomaikaʻi nui i ka maʻalahi a me ka hoʻokō ʻana o nā maʻi.ma Malaki 26, 2015, ua hoʻolaha ʻo Takeda i ka lāʻau lapaʻau Iapana hou ua ʻae ʻia ka lāʻau maʻi diabetes hou ʻo Zafatek e ke Kuhina o ke olakino, hana a me ka pono (MHLW) no ka mālama ʻana i ka maʻi diabetes type 2.Hoʻomaopopo ka ʻae ʻana iā Zafatek i lilo i ka lāʻau hypoglycemic waha mua o ka pule ma ka mākeke ma ka honua, a ke hōʻike nei hoʻi i kahi blockbuster i hāʻule e Takeda i ka mākeke diabetes.
ʻO Trelagliptin kahi dipeptidyl peptidase IV (DPP-4) i hoʻokahi pule i hoʻokahi pule e hoʻomalu i nā pae kōpaʻa koko ma ke koho ʻana a hoʻomau i ka DPP-4.ʻO DPP-4 kahi enzyme e hiki ai ke hoʻomaka i ka hana ʻole o ka incretin (glucagon-like peptide -1 (GLP-1) a me ka glucose-dependent insulinotropic polypeptide (GIP)), kahi mea nui i ka hoʻoponopono glucose koko.Hiki ke hoʻonui i ka hoʻopaʻa ʻana o DPP-4 i ke kō koko koko e pili ana i ka huna ʻana o ka insulin, no laila ke kāohi nei i ke kiʻekiʻe o ke kō koko.Hoʻokumu ʻia ka hoʻouna ʻana o Trelagliptin NDA i ka ʻikepili kūpono a me ka palekana mai kekahi mau hoʻokolohua lapaʻau pae III i mālama ʻia i nā mea maʻi Iapana me ka maʻi diabetes type 2.Ua hōʻoia ʻia ka maikaʻi o Trelagliptin i nā hoʻāʻo āpau, a he palekana maikaʻi a hoʻomanawanui.Hiki i ka Trelagliptin Administration i hoʻokahi pule ke hoʻomalu pono i ke kiʻekiʻe o ke kō koko a manaʻo ʻia e hoʻomaikaʻi i ka mālama ʻana i ka lāʻau lapaʻau.