Enzalutamide CAS 915087-33-1 Maʻemaʻe >99.0% (HPLC)
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui o Enzalutamide (CAS: 915087-33-1) me ke kūlana kiʻekiʻe.Hiki iā Ruifu Chemical ke hāʻawi aku i ka honua holoʻokoʻa, ke kumukūʻai hoʻokūkū, ka lawelawe maikaʻi loa, ka liʻiliʻi a me ka nui nui i loaʻa.Kūʻai iā Enzalutamide (CAS: 915087-33-1),Please contact: alvin@ruifuchem.com
Inoa Kimia | ʻO Enzalutamide |
Nā huaʻōlelo like | MDV-3100;MDV 3100;4-[3-[4-Cyano-3-(Trifluoromethyl)phenyl]-5,5-Dimethyl-4-Oxo-2-Thioxo-1-Imidazolidinyl]-2-Fluoro-N-Methylbenzamide |
Kūlana Kūʻai | I loko o ka waihona, ka hiki ke hana 50 kgs i kēlā me kēia mahina |
Helu CAS | 915087-33-1 |
ʻĀpana Molekala | C21H16F4N4O2S |
Kaumaha Molecular | 464.44 g/mol |
Lae hehee | 198.0~200.0 ℃ |
ʻO ka mānoanoa | 1.49 |
COA & MSDS | Loaʻa |
Ke kumu | Shanghai, Kina |
Brand | Kemika Ruifu |
Nā mea | Nā kikoʻī | Nā hualoaʻa |
Ka nana aku | Keʻokeʻo i ka pauda paʻa keʻokeʻo | Hoʻokō |
Maʻemaʻe / Kaʻina Hanana | >99.0% (HPLC) | 99.57% |
Wai na Karl Fischer | <0.50% | 0.23% |
Koena ma ka Ignition | <0.10% | 0.06% |
Nā Metala Kaumaha (Pb) | ≤20ppm | <10ppm |
Na mea pili | ||
Max.Hoʻokahi haumia | <0.50% | <0.50% |
Huina paumaele | <1.00% | 0.43% |
Infrared Spectrum | Kūlike me ka Hoʻolālā | Hoʻokō |
1H NMR Spectrum | Kūlike me ka Hoʻolālā | Hoʻokō |
Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō me nā kikoʻī i hāʻawi ʻia |
Pūʻolo:ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E hoʻopaʻa paʻa i ka pahu a mālama i loko o kahi hale kūʻai maloʻo a maloʻo (2 ~ 8 ℃) a me kahi hale kūʻai maikaʻi mai nā mea like ʻole.E pale i ka malamalama a me ka wai.
Hoʻouna:Hāʻawi i ka honua ma ka lewa, e FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Nā laʻana?Hāʻawi ka hapa nui o nā huahana i nā laʻana manuahi no ka loiloi maikaʻi, pono e uku ʻia ke kumukūʻai e nā mea kūʻai aku.
Hooia Hale Hana?Welina mai ka loiloi hale hana.E ʻoluʻolu e hoʻopaʻa manawa ma mua.
MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.
Manawa Hoʻouna? Inā i loko o ka waihona, ʻekolu lā hoʻouna ʻia.
Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.
Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.
Hoʻohui Kuʻuna?Hiki ke hāʻawi i nā lawelawe synthesis maʻamau e kūpono i kāu mau pono noiʻi.
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Enzalutamide (CAS: 915087-33-1) he antagonist androgen-receptor (AR) me IC50 o 36 nM, e ālai ana i nā androgens mai ka hoʻopaʻa ʻana i ka androgen receptor a pale i ka translocation nuklea a me ka co-activator recruitment o ka ligand-receptor complex.Ua hōʻike ʻia ʻo Enzalutamide e hoʻoulu i ka apoptosis cell tumor, a ʻaʻohe hana agonist.He moho ʻo Enzalutamide no ka mālama ʻana i ka maʻi prostate pale castration.ʻO Enzalutamide, ka lua o ka hanauna androgen receptor (AR) hōʻailona hōʻailona.Hiki iā ia ke pale i ka hoʻopaʻa ʻana o nā androgens i ka AR, AR nuclear translocation, a me ka hui ʻana o ka AR me DNA.I ʻAukake 2012, ua ʻae ka FDA iā Enzalutamide, i kūʻai ʻia e Medivation a me Astellas Pharma US no ka mālama ʻana i ka maʻi maʻi prostate castration-resistant prostate (CRPC), kūikawā no kēlā mau maʻi i loaʻa mua iā Docetaxel.