CAS 945667-22-1 Maʻemaʻe >99.0% (HPLC) API

ʻO ka wehewehe pōkole:

CAS: 945667-22-1

Maʻemaʻe: >99.0% (HPLC)

Nānā: Pada Keʻokeʻo

API, Mea Kiʻekiʻe, Hana Kalepa

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Chemical Supply pili i waena
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CAS 945667-22-1
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2-(3-Hydroxy-1-Adamantyl)-2-Oxoacetic Acid CAS 709031-28-7

Na Waiwai Kemika:

Nā huaʻōlelo like	BMS-477118 Hydrate;Onglyza Hydrate;(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-Hydroxy-1-Adamantyl)acetyl]-2-Azabicyclo [3.1.0]hexane-3-Carbonitrile Hydrate;(1S,3S,5S)-2-[(S)-2-Amino-2-[(1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl]acetyl]-2-Azabicyclo [3.1.0 ]hexane-3-Carbonitrile Hydrate
Helu CAS	945667-22-1
Helu CAT	RF-PI1992
Kūlana Kūʻai	Ma ka waihona, hoʻonui ʻia a hiki i nā tona
ʻĀpana Molekala	C18H25N3O2·H2O
Kaumaha Molecular	333.43
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Pauda keʻokeʻo
ʻike ʻike	A: IR B: Manawa Paʻa HPLC
Maʻemaʻe / Kaʻina Hanana	>99.0% (HPLC, Ma ke kumu maloʻo)
Waiwai (KF)	5.3%~7.3%
Koena ma ka Ignition	<0.20%
Hoʻokahi haumia	<0.50%
Huina paumaele	<1.00%
Nā Metala Kaumaha	<10ppm
Arsenic (As)	<2ppm
Microbiology
Huina Papa	<1000cfu/g
Huna & Mold	<100cfu/g
E. Coli	ʻinoʻino
S. Aureus	ʻinoʻino
Salmonella	ʻinoʻino
Ola Pahu	24 mahina
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	API;Hoʻohana ʻia no ka mālama ʻana i ka maʻi diabetes type II

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

ʻO ka API (CAS: 945667-22-1) he mea hoʻopaneʻe dipeptidyl peptidase-4 (DPP4) koho a hoʻohuli ʻia i hiki ke hoʻohana ʻia no ka hoʻomohala ʻana i ka mālama ʻana no ka maʻi diabetes type 2.He mea koho a hiki ke hoʻololi i ka DPP4 inhibitor me IC50 o 26 nM a me Ki o 1.3 nM.IC50 waiwai: 26 nM.Pahuhopu: DPP4 in vitro: Loaʻa iā ia he Ki mau o ka 1.3 nM no ka pale ʻana i ka DPP4, ʻo ia ka 10-fold ʻoi aku ka ikaika ma mua o Sitagliptin (ʻelua DPP4 inhibitors) me Ki o 13 a me 18 nM.Eia kekahi, hōʻike ia i ka kikoʻī ʻoi aku ka nui o ka DPP4 ma mua o ka DPP8 a i ʻole DPP9 enzymes (400- a me 75-fold, kēlā me kēia).ʻO ka metablite ikaika o ia mea he ʻelua ʻoi aku ka ikaika ma mua o ka makua.ʻO nā mea ʻelua (CAS: 945667-22-1) a me kāna metabolite i koho nui loa (> 4000-fold) no ka pale ʻana i ka DPP4 i hoʻohālikelike ʻia me kahi ʻano o nā proteases ʻē aʻe.(CAS: 945667-22-1) hoʻemi i ka hoʻohaʻahaʻa ʻana o ka incretin hormone glucagon-like peptide-1, ma laila e hoʻonui ai i kāna mau hana, a pili pū me ka hoʻomaikaʻi ʻana i ka hana β-cell a me ka hoʻopau ʻana i ka huna ʻana o ka glucagon. i ka eliciting marked dose-dependent enhancements in glucose clearance in the dose range 0.13-1.3 mg/kg in ob/ob mice pili i nā mana.