Caspofungin Acetate Cancidas CAS 179463-17-3 Hale Hana API Maʻemaʻe Kiʻekiʻe
Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Caspofungin Acetate
CAS: 179463-17-3
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | ʻO Caspofungin Acetate |
Nā huaʻōlelo like | Cancidas;MK-0991 Acetate;L-743872 Acetate |
Helu CAS | 179463-17-3 |
Helu CAT | RF-API58 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C52H88N10O15·2C2H4O2 |
Kaumaha Molecular | 1213.42 |
Lae hehee | >197 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pauda keʻokeʻo a ʻaneʻane keʻokeʻo |
ʻIkepili IR | IR: Pono ka laʻana o ka hoʻāʻo ʻana i ka Caspofungin Acetate Reference Standard |
ʻIke HPLC | HPLC: Pono ka manawa paʻa o ka piko kumu i loaʻa mai ka hopena hoʻāʻo me ka mea i loaʻa mai ka hopena maʻamau, e like me ka hoʻāʻo ma Assay |
Ka malamalama a me ke kala | Pono ka hoʻonā ʻana e akaka a kala ʻole |
Hoʻololi kikoʻī | -102.0° ~ -108.0° |
pH | 5.0-7.0 |
Wai | ≤10.0% |
Na mea pili I | (Ma ka Anhydrous and Acetic Acid Free Basis) |
haumia A | ≤0.10% |
haumia B | ≤0.10% |
haumia D | ≤0.30% |
haumia E | ≤0.10% |
Ka haumia ʻole i hōʻike ʻia F | ≤0.10% |
ʻO ka haumia ʻole i hōʻike ʻia G | ≤0.10% |
Pneumocandin B0 | ≤0.10% |
Hoʻokahi i ʻike ʻole ʻia ka haumia | ≤0.10% |
Huina paumaele | ≤1.0% |
Na Mea Pili II | ≤0.10% |
Nā mea hoʻoheheʻe koena | |
Ethyl Acetate | ≤5000ppm |
Ethanol | ≤5000ppm |
Methanol | ≤5000ppm |
Acetonitrile | ≤410ppm |
Tetrahydrofuran | ≤720ppm |
Acetic Acid Content | 9.0%~11.0% (Ka helu ʻia ma ke kumu Anhydrous) |
Ethylendiamine | ≤0.10% |
Koena ma ka Ignition | ≤0.10% |
Nā Metala Kaumaha (e like me Pb) | ≤10ppm |
Hana ʻIke / ʻIke | 97.0%~102.0% (Ma ka Anhydrous a me Solvent Free Basis) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Mea Hana Lapaʻau Hoʻoikaika (API) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Caspofungin Acetate (CAS: 179463-17-3) kahi lāʻau antifungal lipopeptide.ʻO ka Caspofungin acetate no ka injection i'āpono muaʻia e FDA ma USA, a me ka EMEA maʻEulopa, i ka makahiki 2001. ʻO Caspofungin Acetate he wai hoʻoheheʻe wai, paʻa, aza-substituted semisynthetic derivative o Pneumocandin B, kahi huahana fermentation o ka haʻiki Zalerion arboricola.ʻO ka lipopeptide caspofungin, kaohi i ka synthesis o 1,3-beta-D-glucans i loaʻa wale i loko o ka pā hale fungal, kahi e alakaʻi ai i ka lysis kikoʻī o nā cell pathogenic.He fungicidal ka pūhui ma mua o ka fungistatic, kahi hiʻohiʻona maʻamau i waena o nā mea antifungal.ʻOi aku ka ikaika o Caspofungin ma mua o ka amphotericin B, flucytosine, fluconazole a me itraconazole e kūʻē i nā ʻano Candida.