Cyano-Irbesartan CAS 138401-24-8 Maʻemaʻe >98.0% (HPLC) Hale Hana Kūwaena ʻo Irbesartan
ʻO Ruifu Chemical Supply Irbesartan Intermediates:
Irbesartan CAS 138402-11-6
Cyano-Irbesartan CAS 138401-24-8
Trityl Irbesartan CAS 138402-10-5
TTBB CAS 124750-51-2
Irbesartan ʻaoʻao Chain Hydrochloride CAS 151257-01-1
Inoa Kimia | Cyano-Irbesartan |
Nā huaʻōlelo like | CyanoIrbesartan;Irbesartan Cyano haumia;Irbesartan Hydrocarbon;Irbesartan haumia 6;2-Butyl-3-[[2'-cyano-[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4,4]non-1-en-4-one;4'-[(2-Butyl-4-oxo-1,3-diazaspiro[4,4]non-1-en-3-yl)methyl]-[1,1'-biphenyl]-2-carbonitrile |
Helu CAS | 138401-24-8 |
Helu CAT | RF-PI1892 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C25H27N3O |
Kaumaha Molecular | 385.51 |
ʻO ka mānoanoa | 1.15 |
Solubility (Soluble in) | Methanol |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keokeo a aneane keokeo ka pauda i ke aniani |
Maʻemaʻe / Kaʻina Hanana | >98.0% (HPLC) |
Maemae | >97.0% (Me ka Hui Nitrogen) |
Lae hehee | 91.0 a 95.0 ℃ |
Nalo ma ka maloo | <1.00% |
Hoʻokahi haumia | <1.00% |
Nā Metala Kaumaha | <20ppm |
Infrared Spectrum | Kūlike i ka hoʻolālā |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Kūwaena / haumia o Irbesartan (CAS: 138402-11-6) |
Pūʻolo: ʻOmole, ʻeke ʻeke Aluminum, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
ʻO Cyano-Irbesartan (CAS: 138401-24-8) kahi waena a haumia paha o Irbesartan (CAS: 138402-11-6).ʻO Irbesartan kahi mea hoʻokae hoʻokipa angiotensin II (Angiotensin II, Ang II).Hoʻokaʻawale ʻia nā mea hoʻokipa Angiotensin II i ʻelua ʻano: AT1 a me AT2.Hoʻopili koho ʻo Irbesartan i ka mea hoʻokipa AT1 o AnglI.Hiki iā ia ke pale i ka hoʻololi ʻana o Ang i Ang, hiki ke kūʻē i ka angiotensin-converting enzyme 1 receptor (AT1).ʻO ka hopena antagonistic ma AT1 he 8500 manawa ma mua o AT2.Hiki iā ia ke pale i ka hoʻopaʻa ʻana o Ang a me AT1 receptor ma o Inhibit vasoconstriction a me ka hoʻokuʻu ʻana o ka aldosterone, ka hopena i kahi hopena hypotensive.ʻAʻole ʻae kēia huahana i ka angiotensin hoʻololi i ka enzyme (ACE), renin, nā mea hoʻokipa hormone ʻē aʻe, ʻaʻole hoʻi e kāohi i nā kahawai ion e pili ana i ka hoʻoponopono ʻana i ke koko a me ke koena sodium.Hiki i ka Irbesartan ke hōʻemi i ka hoʻoponopono hou ʻana o ka myocardium, a laila e hōʻemi i ka nui o ka make o nā mea maʻi me ka hypertension.ʻO kēia ka lāʻau lapaʻau maikaʻi loa no ka mālama ʻana i ka hypertension a me nā maʻi cardiovascular.