ʻO Dantrolene Sodium Salt Hydrate CAS 14663-23-1 API Hale Hana Kiʻekiʻe
Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Dantrolene Sodium Salt Hydrate
CAS: 14663-23-1
Hoʻomaha ʻAiʻo iwi.Kāleka Kāleka Kāleka
API no ke kūlana kiʻekiʻe, hana kālepa
| Inoa Kimia | ʻO Dantrolene Sodium Salt Hydrate |
| Nā huaʻōlelo like | 1-[5-(4-Nitrophenyl)furfurylideneamino]hydantoin Sodium Salt Hydrate |
| Helu CAS | 14663-23-1 |
| Helu CAT | RF-API78 |
| Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
| ʻĀpana Molekala | C14H11N4NaO5 |
| Kaumaha Molecular | 338.25 |
| Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia ma DMSO |
| Kūlana Hoʻouna | Hoʻouna ʻia ma lalo o ka wela ambient |
| Brand | Kemika Ruifu |
| 'ikamu | Nā kikoʻī |
| Ka nana aku | Melemele-Alani i ka Alani Crystalline Pauda.ʻAʻohe hōʻike ʻike ʻia o ka haumia e nā mea ʻē |
| ʻIkepili A | ʻO ka IR Absorption (197K) |
| ʻIkepili B | ʻO ka manawa paʻa o ka piko nui i loko o ka chromatogram o ka hoʻomākaukau ho'āʻo e pili ana i kēlā i loko o ka chromatogram o ka hoʻomākaukau maʻamau, e like me ka loaʻa ʻana ma ka assay. |
| ʻIkepili C | Hoʻokō i nā koi o ka hoʻāʻo ahi no ka Sodium (191) |
| ʻIkepili D | Māhele 1: Ua hoʻokumu ʻia kahi ʻano nui, keʻokeʻo, crystalline precipitate Mahele 2: ʻAʻole e nalowale ka ea Mahele 3: Hoʻoheheʻe ʻia ka wai Mahele 4: ʻAʻohe wai i hoʻokumu ʻia |
| Waiwai (na KF) | 14.5%~17.0% |
| Ka nui o ka ʻāpana | 90% emi ma mua o 200um |
| Hoʻāʻo | 90.0%~96.0% o C14H10N405 ma ke kumu anhydrous |
| Na mea pili | (HPLC, Wahi%) |
| Huihui pili A | ≤0.15% |
| Huihui pili B | ≤0.50% |
| Huihui pili C | ≤0.30% |
| Nā mea hoʻoheheʻe koena | |
| Ethanol | ≤2000ppm |
| Methanol | ≤2000ppm |
| Acetone | ≤2000ppm |
| DMF | ≤620ppm |
| Nā Metala Kaumaha | ≤10ppm |
| Ola Pahu | 2 Makahiki |
| Kūlana hoʻāʻo | ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP) |
| Hoʻohana | Hoʻomaha ʻAiʻo iwi.Kāleka Kāleka Kāleka |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Dantrolene Sodium Salt Hydrate (CAS 14663-23-1), he mea hoʻopaneʻe mole liʻiliʻi o Ryanodine receptor antagonist a me kahi mea hoʻopaneʻe kanal calcium.ʻO Dantrolene Sodium Salt he mea hoʻomaha hoʻomaha ʻiʻo iwi, kahi e kāohi ai i ka hoʻokuʻu ʻana o Ca 2+ intracellular mai ka sarcoplasmic reticulum.Hoʻokuʻu ʻia ka hoʻokuʻu ʻana o Ca2+ mai ka sarcoendoplasmic reticulum, pili ikaika i ka hauʻoli a me ka ʻoki ʻana o nā ʻiʻo, hoʻopuka i kahi hopena hoʻomaha hoʻomaha i hoʻopili ʻia me Dantrolene.Hoʻopili ʻia ka neurotoxicity i hōʻike ʻia e ka hana glutamate i ka piʻi nui ʻana i nā pae cytoplasmic Ca2 +, a ua hōʻike ʻia ʻo Dantrolene ma ke ʻano he neuroprotective agent e kūʻē i ka neurotrasmitter-induced excitotoxicity.ʻO Dantrolene, ʻo Sodium Salt ka mea paʻa o RyR-1 a me RyR-3.
