DCC CAS 538-75-0 Dicyclohexylcarbodiimide Maʻemaʻe >99.0% (GC) Hale Hana Hana Hoʻohui Petide Coupling Reagent

Hoʻohana ʻia ʻo DCC (N,N'-Dicyclohexylcarbodiimide, CAS: 538-75-0) i ka kemika peptide ma ke ʻano he mea hoʻohui.Hoʻohana nui ʻia no ka synthesis artificial o peptides Condensation o nā waikawa amino.No ka laʻana, i ka Fmoc-solid phase synthesis, ʻo ka pūʻulu carboxyl o kahi waikawa amino e hana i kahi paʻa amide me ka pūʻulu amino o kekahi waikawa amino.I mea e ʻoluʻolu ai ka pūʻulu carboxyl i ka hoʻouka ʻana o nā nucleophiles, pono e hoʻāla ʻia ka atom oxygen i hoʻopiʻi ʻia i kahi hui haʻalele maikaʻi aʻe, a ʻo DCC ke kuleana.ʻO ka oxygen atom o ka hui carboxyl ma ka amino acid e hana ma ke ʻano he nucleophile e hoʻouka i ke kalapona kalapona i waenakonu o ka mole DCC i hui ai ka DCC me ka hui carboxyl e hana i kahi ester, e hana ana i ka hoʻouka nucleophilic o ka hui amino maʻalahi e hoʻokō i ka reagent hui.

Hoʻohana ʻia ʻo DCC no ka synthesis a me ka dehydration o ka amikacin a me nā waikawa amino.he maikaʻi haʻahaʻa haʻahaʻa biochemical dehydrating agent a hoʻohana pū ʻia no ka synthesis o nā waikawa, anhydrides, aldehydes, ketones, etc. Ma Iapana, hoʻohana ʻia nā mea hoʻohana no ka glutathione no 90% o ka pau ʻana.Ke hoʻohana ʻia ka huahana e like me ka dehydration a me ka condensing agent, hiki ke hoʻopili ʻia i ka manawa pōkole ma ka lumi wela, a ʻo ka huahana ma hope o ka hopena he dicyclohexylurea.Ma muli o ka liʻiliʻi loa o ka solubility o ka huahana i loko o ka solvent organik, maʻalahi ka hoʻokaʻawale ʻana o ka huahana hopena;i ka manawa like, no ka paʻakikī o ka hoʻoheheʻe ʻana o ka huahana i ka wai, hiki ke hoʻomau i ka hopena i loko o kahi hopena wai.Hoʻohana ʻia ka huahana no ka synthesis o nā peptides a me nā waikawa nucleic.Hiki i ka hoʻohana ʻana i kēia huahana ke hoʻohui maʻalahi i nā peptides mai nā pūhui me nā hui carboxyl manuahi a me nā pūʻulu me nā pūʻulu amino manuahi i ka lumi wela, a kiʻekiʻe loa ka hua.Hoʻohana ʻia no ka hana ʻana o ka hypertensives a me ka cyclic adenosine monophosphate.hoʻohana ʻia e like me ka biochemical reagent a me ka organik synthesis dehydration condensing agent.