DEPBT CAS 165534-43-0 Peptide Coupling Reagent Maʻemaʻe >99.0% (HPLC) Hale Hana

ʻO 3- (Diethoxyphosphoryloxy) -1,2,3-Benzotriazin-4 (3H) -one (DEPBT) (CAS: 165534-43-0) he mea hoʻohui peptide i hoʻohana ʻia i ka peptide synthesis.Hōʻike ia i ke kū'ē kū'ē i ka racemization.ʻO DEPBT kahi reagent hui e hoʻomaʻamaʻa i ka hoʻokumu ʻana i ka paʻa amide a kūʻē pū i ka racemization.Ua hōʻike ʻia ʻoi aku ka maikaʻi ma mua o ka phosphonium a me ka uronium coupling reagents.
ʻO DEPBT, ka reagent maikaʻi loa no ka hoʻokumu ʻana i ka paʻa amide i ka synthesizing molekole paʻakikī a no ka cyclization peptide.He kūpono no ka hoʻonā a me ka synthesis paʻa.Ua kūpono ʻo DEPBT me ka hoʻonā a me SPPS.
ʻO DEPBT kahi mea hoʻohui hui organophosphorous i hoʻohana ʻia i ka kemika peptide.Maikaʻi ka DEPBT i ka synthesis o nā peptides linear, cyclic a me sterically hindered, i ka hopena a me ka synthesis paʻa paʻa, e loaʻa ana nā hua kiʻekiʻe me nā kinetics wikiwiki a me ka paʻa ʻana o ka hoʻonohonoho.Hiki ke hoʻopili maʻalahi ʻia ka DEPBT, ʻo ia ka crystalline phosphate stable no nā mahina a hōʻike pinepine i nā hana ʻoi aku ka maikaʻi ma mua o nā paʻakai phosphonium a me uronium.ʻO ka mea nui, ma mua o DEPBT ʻaʻole pono e pale i ka hui hydroxyl i nā amino acids (e like me tyrosine, serine, a me threonine) a me ka hui imidazole o histidine.No laila, hiki ke hoʻohana ʻia ka DEPBT i ka synthesis o nā amino alcohols a me N-glycopeptides.Loaʻa ka DEPBT i ka noi i ka synthesis o nā peptides bioactive a me nā huahana kūlohelohe paʻakikī.