Desmopressin Acetate CAS 16789-98-3 Peptide Purity (HPLC) ≥98.5% Factory

Nā hōʻailona pōʻino Xn - ʻino
Nā Code Risk 20 - He pōʻino ma ka inhalation
Hōʻike Palekana 36 - E ʻaʻahu i nā lole pale kūpono.
WGK Kelemānia 3

ʻO Desmopressin Acetate (CAS: 16789-98-3) ʻo ia hoʻi, 1-cysteine ​​deamination a me 8-D-arginine ma kahi o 8-l-arginine, i ʻike ʻia ʻo arginine vasopressin, he mea hoʻohālikelike o ka arginine vasopressin maoli, kahi derivative o ʻO ka vasopressin, ʻoi aku ka ikaika o kāna hopena antidiuretic ma mua o ka vasopressin, akā ʻaʻohe hopena vasoconstrictor, nā hopena ʻaoʻao o ka lāʻau lapaʻau, ke kino no ka congenital a i ʻole ka lāʻau lapaʻau-induced platelet dysfunction, uremia, ate cirrhosis a me nā kumu i ʻike ʻole ʻia e ka lōʻihi o ke kahe koko;Hiki ke hoʻohana ʻia e hoʻomalu a pale i ke koko i ka wā o ka ʻoki liʻiliʻi;Central diabetes insipidus.I kēlā me kēia hihia, hiki i kēia huahana ke hana i ka maikaʻi i nā poʻe maʻi me nā maʻi ʻōnaehana urinary haʻahaʻa, pinepine ʻole i nā maʻi me ka maʻi Type IIB von Willebrand.
Ka hana lāʻau lapaʻau: Desmopressin Acetate aia ka desmopressin i like ke ʻano me ka arginine vasopressin maoli.ʻO ia ka ʻokoʻa ma waena o arginine vasopressin, no ka hapa nui o ka amino acid a me D arginine e pani iā ​​L Arginine.ʻO kēia mau hoʻololi hoʻololi e hoʻolōʻihi i ka lōʻihi o ka hana o ka lāʻau lapaʻau o desmopressin me ka ʻole o nā hopena ʻaoʻao o ke kaomi.Ua hōʻike ʻia kekahi mau haʻawina he mea nui ka hopena o ka anti-enuresis, ʻo ia paha ma muli o ka piʻi ʻana o nā pae arginine vasopressin i ke koko o nā keiki i ka pō, a laila hoʻopaʻa i ka mimi, hoʻemi i ka nui o ka mimi a me ke kaomi intravascular, hoʻemi i ka ʻāʻī a ʻokiʻoki detrusor.
ʻO kona kūpono, maʻalahi o ka hoʻokele (intrasal), lōʻihi ka lōʻihi o ka hana, a me ka nele o nā hopena ʻaoʻao e lilo ia i lāʻau koho no ka mālama ʻana i ka maʻi diabetesinsipidus waena.Hiki ke hāʻawi ʻia i intramuscularly a i ʻole intravenously.ʻOi aku ka maikaʻi o ka vasopressin injection a me nā antidiuretics waha no ka hoʻohana ʻana i nā keiki.Hōʻike ʻia ia i ka mālama ʻana i ka polydipsia no ka manawa lōʻihi a me ka polyuria i hui pū ʻia me ka trauma i, a i ʻole ka ʻoki ʻana i ka ʻāina pituitary.
Hoʻohana maʻi: Desmopressin, e like me kāna paʻakai acetate, he analogue synthetic o vasopressin kahi i nele ai ka N terminal Cys i kāna hana α-amino (1-Deamino) a ma kahi o Arg8 e like me kāna D-isomer (D-Arg8) , pela ka acronym kalepa DDAVP.ʻO ka heleʻana o D-Arg a me ka loaʻaʻole o ka N-terminal amine i loko o ka hale desmopressin ua hoʻonui i kona hapalua o ke ola e hiki ai ke loaʻa no ka waha, makua, a iʻole ka ihu.Hoʻohana ʻia ia e nā ʻekolu o kēia mau ala o ka hoʻokele ʻana e pale a hoʻomalu i ka polydipsia (make wai nui), polyuria, a me ka dehydration o nā mea maʻi me ka maʻi diabetes insipidus ma muli o ka hemahema o ka vasopressin.Ua ʻae ʻia hoʻi no ka mālama ʻana i ka enuresis nocturnal (bed-wetting), i manaʻo ʻia ma muli o ka nele o ka piʻi ʻana o ka pō maʻamau i nā pae vasopressin.Ua ʻike ʻia ʻo Desmopressin e hoʻonui i ka mea plasma VIII (antihemophilic factor) a me ka plasminogen activator.No laila ua ʻae ʻia ia e ka US FDA no ka hoʻohana ʻana, makua a me ka ihu, i ka hoʻohaʻahaʻa ʻana i ka manawa a i ʻole ka trauma-induced bleeding episodes i nā maʻi me ka hemophilia A a me ke ʻano I maʻi ʻo Von Willebrand, inā ʻoi aku ka nui o kā lākou plasma factor VIII ma mua o 5%.ʻO Stimate, ʻo ka ehu ihu i hoʻohana ʻia i ka mālama ʻana i nā maʻi me ka hemophilia A a me ke ʻano I ka maʻi ʻo Von Willebrand, he 15-paʻipaʻi ka nui o ka DDAVP nasal spray;Hoʻohana ʻia ka mea hope i ka mālama ʻana i ka maʻi diabetes insipidus.