Diethylphosphonoacetic Acid CAS 3095-95-2 Maʻemaʻe >99.5% (HPLC) Afatinib Dimaleate Intermediate Factory

ʻO ka wehewehe pōkole:

Inoa Kemika: Diethylphosphonoacetic Acid

CAS: 3095-95-2

Maʻemaʻe: >99.5% (HPLC)

Ke ʻano: wai kala ʻole

Waena o Afatinib Dimaleate (CAS: 850140-73-7)

ʻO ke kūlana kiʻekiʻe, ka hana kālepa

E-Mail: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

ʻO Ruifu Nā Kūwaena Hoʻolako Kimia o Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
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Diethylphosphonoacetic Acid CAS 3095-95-2
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(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl) oxy)quinazolin-4-AmineCAS 314771-88-5

Na Waiwai Kemika:

Inoa Kimia	Diethylphosphonoacetic Acid
Nā huaʻōlelo like	2-(Diethoxyphosphoryl)acetic Acid;(Diethoxyphosphinyl)acetic Acid;Diethyl Carboxymethylphosphonate;NSC 272281
Helu CAS	3095-95-2
Helu CAT	RF-PI2024
Kūlana Kūʻai	Ma ka waihona, ka mana hana 30MT / mahina
ʻĀpana Molekala	(C2H5O)2P(O)CH2CO2H
Kaumaha Molecular	196.14
Lae paila	150 ℃/0.05 mmHg (māmā)
ʻO ka mānoanoa	1.220 g/mL ma 25 ℃ (māmā)
Hōʻike Hōʻike	n20/D 1.445 (māmā)
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Wai kala ʻole
ʻIkepili (HPLC)	ʻO ka manawa paʻa o ka piko nui i loaʻa mai ka hāpana i loko o 5% o ka hāpana kuhikuhi.
Maʻemaʻe / Kaʻina Hanana	>99.5% (HPLC)
Infrared Spectrum	Kūlike i ka hoʻolālā
Proton NMR Spectrum	Kūlike i ka hoʻolālā
Māmā (KF)	<0.50%
Huina paumaele	<0.50%
Kūlana hoʻāʻo	Kūlana ʻoihana
Hoʻohana	Waena o Afatinib Dimaleate (CAS: 850140-73-7)

Pūʻolo a me ka waiho ʻana:

Pūʻolo: Fluorinated Bottle, 25kg/ Drum, a i ʻole e like me ka makemake o ka mea kūʻai aku

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai

Pono:

FAQ:

Noi:

Diethylphosphonoacetic Acid (CAS: 3095-95-2), Hana ma ke ʻano he nucleophile no nā ʻano hoʻohui nucleophilic no ka synthesis o allene epoxides Reactant no: Stereoselectivity study of the Staudinger reaction;Hoʻokumu enantioselective o nā diols ma o ka epoxidation a me ka hydration reactions;Nā hopena o Horner-Wadsworth-Emmons;Hoʻonohonoho hou ʻia ka chelation mamao ʻo Ireland-Claisen;ʻO nā pane ʻo Ugi-Dieckmann no ka hoʻohui ʻana i nā derivatives waikawa tetramic;Hoʻohana ʻia e hana i nā phosphonoester intermediates no intramolecular HEW reactions.ʻO ka Diethylphosphonoacetic Acid kahi mea waena o Afatinib Dimaleate (CAS: 850140-73-7).Ua ʻae ʻia ʻo Afatinib Dimaleate e ka US Food and Drug Administration (FDA) i ka makahiki 2013 no ka mālama ʻana i ka maʻi maʻi ʻaʻai liʻiliʻi liʻiliʻi (NSCLC).Ma keʻano kikoʻī, ua ʻae ʻia ia no nā mea maʻi e hōʻike ana me nā ʻōpū NSCLC metastatic i loaʻa i ka epidermal growth factor receptor (EGFR) exon deletions a i ʻole exon 21 mutations.ʻO Afatinib Dimaleate kahi mea hoʻopaneʻe kovalent o ErbB tyrosine kinases (tyk), ka mea e hoʻohaʻahaʻa i ka hōʻailona ErbB ma o ka hoʻopaʻa ʻole ʻana o nā pūnaewele pili EGFR tyk.