(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6 Maʻemaʻe >99.0% (GC) Afatinib Dimaleate Intermediate Factory
ʻO Ruifu Nā Kūwaena Hoʻolako Kimia o Afatinib
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Inoa Kimia | (Dimethylamino)acetaldehyde Diethyl Acetal |
Nā huaʻōlelo like | 2,2-Diethoxy-N,N-Dimethylethylamine;N-(2,2-Diethoxyethyl)dimethylamine;2,2-Diethoxy-N,N-Dimethylethan-1-Amine |
Helu CAS | 3616-56-6 |
Helu CAT | RF-PI2031 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C8H19NO2 |
Kaumaha Molecular | 161.25 |
ʻO ka ʻike | ʻAiʻoniʻoni |
Lae paila | 60 ℃/5 mmHg |
Lae Flash | 45 ℃ |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Wai ʻaʻohe kala ʻole |
Maʻemaʻe / Kaʻina Hanana | >99.0% (GC) |
Hōʻike Hōʻikeʻike N20/D | 1.410~1.414 |
Kaumaha kiko (20/20 ℃) | 0.865~0.870 |
Proton NMR Spectrum | Kūlike i ka hoʻolālā |
Huina paumaele | <1.00% |
Nā Metala Kaumaha (e like me Pb) | ≤20ppm |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Nā Kūwaena Lapaʻau;Afatinib Dimaleate;Sumatriptan |
Pūʻolo: Fluorinated Bottle, 25kg/Drum, a i ʻole e like me ka makemake o ka mea kūʻai aku
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;E pale i ka malamalama a me ka wai
(Dimethylamino)acetaldehyde Diethyl Acetal (CAS: 3616-56-6) hoʻohana ʻia ma ke ʻano he lāʻau waena.(Dimethylamino)acetaldehyde Diethyl Acetal hiki ke hoʻohana i ka synthesis o Afatinib Dimaleate (CAS: 850140-73-7), Sumatriptan (CAS: 103628-46-2).ʻO Afatinib (inoa kālepa ʻo Gilotrif ma US a me Giotrif ma ʻEulopa, ma mua ʻo Tomtovok a me Tovok) he lāʻau lapaʻau i ʻae ʻia ma ʻAmelika Hui Pū ʻIa, ʻEulopa, Taiwan, Mexico, Chile a me Iapana a me nā ʻāina ʻē aʻe no ka lāʻau lapaʻau mua o nā maʻi me ka ʻokoʻa. nā ʻano metastatic (EGFR mutation positive) non-small cell lung carcinoma (NSCLC), i hoʻomohala ʻia e Boehringer Ingelheim.Hana ʻo Afatinib ma ke ʻano he mea hiki ʻole ke hoʻololi i ka covalent inhibitor o thereceptor tyrosine kinases epidermal growth factor receptor (EGFR) a me erbB-2 (HER2).ʻO Sumatriptan ka triptan mua i ʻae ʻia (1991) no ka mālama ʻana i ka ʻeha o ka migraine.Loaʻa iā ia ka bioavailability haʻahaʻa ma waena o nā triptans ma muli o kona lipophilicity haʻahaʻa.ʻO ka loaʻa ʻana o nā ʻano ʻano like ʻole (ʻo ia hoʻi, he papa waha, he SC injection, nasal spray formulation, a me kahi suppository) hiki ke maʻalahi o ka hoʻoponopono ʻana i nā pono o kēlā me kēia maʻi, no laila e hana ai ka sumatriptans i lāʻau lapaʻau maikaʻi loa no ka mālama ʻana i ka migraine. poʻo poʻo.Loaʻa i ka Sumatriptan kahi wikiwiki loa o ka hana ma o SC injection a i ʻole ka hoʻokele nasal spray.