Doxorubicin Hydrochloride CAS 25316-40-9 API USP Hale Hana Ma'ema'e Ki'eki'e
Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Doxorubicin Hydrochloride
CAS: 25316-40-9
Antitumor Antibiotic Agen.Kāohi i ka DNA Topoisomerase II
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | ʻO Doxorubicin Hydrochloride |
Nā huaʻōlelo like | Doxorubicin HCl;Adriamycin HCL;Hydroxydaunorubicin Hydrochloride |
Helu CAS | 25316-40-9 |
Helu CAT | RF-API38 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C27H30ClNO11 |
Kaumaha Molecular | 579.98 |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | ʻAlani-ʻulaʻula a i ʻole ʻulaʻula Crystalline Powder;ʻAʻohe hōʻike ʻike ʻia o ka haumia e nā mea ʻē |
Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i ka wai a me ka methanol;hiki ke hoʻoheheʻe iki i ka ethanol;ʻaʻole hiki ke hoʻoheheʻe ʻia i ka acetone |
ʻIkepili A | Kūlike ka spectrum IR i ka spectrum IR o ka maʻamau kuhikuhi |
ʻIkepili B | ʻO ka manawa paʻa o ka doxorubicin peak i ka chromatogram o ka hoʻomākaukau Assay e pili ana i kēlā i loko o ka chromatogram o ka hoʻomākaukau maʻamau, e like me ka loaʻa ʻana ma ka Assay. |
pH | 4.0~5.5 |
Waiwai | ≤4.0% |
Na mea pili | |
haumia A (Doxorubicinol) | ≤0.50% |
ʻO nā mea haumia ʻē aʻe i ʻike ʻole ʻia | ≤0.20% |
Huina paumaele i ike ole ia | ≤0.50% |
Huina paumaele | ≤1.0% |
Hoʻāʻo | 98.0%~102.0% o C27H30ClNO11 i helu ʻia ma ke kumu anhydrous, solvent-free. |
Nā mea hoʻoheheʻe koena | |
Acetone | ≤0.50% |
Acetone + Ethanol | ≤2.5% |
Methanol | ≤0.30% |
Dichloromethane | ≤0.06% |
Kūlana hoʻāʻo | ʻAmelika Hui Pū ʻIa Pharmacopeia (USP) Reference Standard |
Hoʻohana | Mea Hana Lapaʻau Hoʻoikaika (API) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
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ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o Doxorubicin Hydrochloride (CAS: 25316-40-9) me ke kūlana kiʻekiʻe.ʻO Doxorubicin hydrochloride, kahi lāʻau antibiotic anthracycline cytotoxic, he mea hoʻohana lāʻau lapaʻau anti-cancer.ʻO ka Doxorubicin hydrochloride kahi mea hoʻopaneʻe DNA topoisomerase I a me topoisomerase II me IC50s o 0.8 μM a me 2.67 μM, kēlā me kēia.Hoʻokomo ʻo Doxorubicin hydrochloride i ka apoptosis a me ka autophagy.ʻO Doxorubicin kahi mea hana antitumour ikaika e kūʻē i kahi ākea ākea o nā maʻi maʻi, me ka leukemias, sarcomas, ka maʻi maʻi umauma, ka maʻi kanesa liʻiliʻi a me ka maʻi maʻi ovarian.
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