Entecavir Monohydrate CAS 209216-23-9 API Hale Hana Ki'eki'e Hepatitis B

ʻO ka wehewehe pōkole:

Inoa Kemika: Entecavir Monohydrate

CAS: 209216-23-9

ʻAno: Keʻokeʻo a ʻaneʻane keʻokeʻo Crystalline Powder

Hoʻohana ʻia ka lāʻau antiviral i ka mālama ʻana i ka maʻi Hepatitis B

API no ke kūlana kiʻekiʻe, hana kālepa

Inquiry: alvin@ruifuchem.com


Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

Hāʻawi Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Entecavir Monohydrate
CAS: 209216-23-9
Hoʻohana ʻia i ka mālama ʻana i ka maʻi Hepatitis B
API no ke kūlana kiʻekiʻe, hana kālepa

Na Waiwai Kemika:

Inoa Kimia Entecavir Monohydrate
Nā huaʻōlelo like Entecavir Hydrate;9-[(1S,3R,4S)-4-Hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]guanine Monohydrate
Helu CAS 209216-23-9
Helu CAT RF-API79
Kūlana Kūʻai Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram
ʻĀpana Molekala C12H17N5O4
Kaumaha Molecular 295.3
Lae hehee >220 ℃
ʻO ka mānoanoa 1.81
Kūlana Hoʻouna Hoʻouna ʻia ma lalo o ka wela ambient
Brand Kemika Ruifu

Nā kikoʻī:

'ikamu Nā kikoʻī
Ka nana aku Keʻokeʻo a ʻaneʻane keʻokeʻo Crystalline pauda
Ka hikiwawe Hiki ke hoʻoheheʻe ʻia i loko o ka Dimethylformamide, hiki ke hoʻoheheʻe ʻia i ka wai, ethanol a me ka methanol
ʻIkepili IR Kūlike ke kiko o ka hāpana me ka maʻamau kuhikuhi
ʻIke HPLC ʻO ka manawa paʻa o ka hāpana hoʻāʻo e pili ana i ka maʻamau kuhikuhi
Waiwai (na KF) 5.5%~6.5%
Hoʻololi Optical kikoʻī +24.0° a i +30.0° (DMF: MeOH=1:1 C=1%) (ma ka mea anhydrous)
Koena ma ka Ignition ≤0.10%
Na mea pili  
ʻO Furoentecavir ≤0.10%
Entecavir 1-Epimer ≤0.10%
Entecavir 3-Epimer ≤0.10%
8-Methyoxy Entecavir ≤0.10%
Entecavir 4-Epimer ≤0.10%
8-Hydroxy Entecavir ≤0.10%
4-Dimethylsilyl Entecavir ≤0.10%
Entecavir Huihui Pili A ≤0.10%
ʻO nā mea haumia ʻole i hōʻike ʻia ≤0.10%
Huina paumaele ≤0.30%
Nā mea hoʻoheheʻe koena
Methanol ≤600ppm
Dichloromethane ≤300ppm
Ethyl Acetate ≤1000ppm
Tetrahydrofuran ≤720ppm
Toluene ≤890ppm
Benzyl Chloride ≤1000ppm
Benzyl Alcohol ≤1000ppm
Palena Microbial
Huina Aerobic ≤100cfu/g
Huna a me ka Molds ≤10cfu/g
Escherichia Coli ʻAʻole pono e ʻike ʻia
Nā Metala Kaumaha ≤10ppm
Hoʻāʻo 98.0%~102.0% (HPLC; ma ke kumu anhydrous)
Ka nui o ka ʻāpana Pono ka 95% o nā ʻāpana i loko o 125um
Kūlana hoʻāʻo ʻOihana Kūlana;ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP).
Hoʻohana Hoʻohana ʻia ka lāʻau antiviral i ka mālama ʻana i ka maʻi Hepatitis B

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.

Pono:

1

FAQ:

Noi:

ʻO ka Entecavir Monohydrate (CAS 209216-23-9) he lāʻau antiviral waha i hoʻohana ʻia i ka mālama ʻana i ka maʻi Hepatitis B (HBV).ʻO ka Entecavir Monohydrate kahi analog nucleoside (ʻoi aku ka kikoʻī, kahi analogue guanine) e kāohi ana i ka hoʻohuli ʻana, ka hoʻopiʻi DNA a me ka transcription i loko o ka vira.He ʻano hou ia o ka cyclopentyl acyl guanosine anti-Hepatitis B nā lāʻau maʻi me kona hopena lāʻau lapaʻau e like me Entecavir.Hoʻohana ʻia ia i ka mālama ʻana i ka maʻi Hepatitis B maʻi maʻi i loaʻa i ka hoʻopiʻi viral ikaika, hoʻonui i ka serum transaminase ALT a i ʻole nā ​​​​ʻeha ikaika i hōʻike ʻia mai ka histology o ka ate.ʻO ka Entecavir Monohydrate he mea hoʻopaneʻe ikaika a koho i ka HBV, me kahi EC50 o 3.75 nM i loko o ka cell HepG2.ʻO Entecavir kahi mea hoʻopaneʻe transcriptase.Kāohi ia i ka Hepatitis B Virus (HBV) mai ka hoʻonui ʻana a hoʻemi i ka nui o ka maʻi maʻi i loko o ke kino.

E kākau i kāu leka ma aneʻi a hoʻouna mai iā mākou