Epalrestat CAS 82159-09-9 Maʻemaʻe >99.5% (HPLC) Hale Hana
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui o Epalrestat (CAS: 82159-09-9) me ke kūlana kiʻekiʻe.Hiki iā Ruifu Chemical ke hāʻawi i ka hāʻawi honua, ke kumukūʻai hoʻokūkū, ka liʻiliʻi a me ka nui o ka nui.Kūʻai iā Epalrestat,Please contact: alvin@ruifuchem.com
| Inoa Kimia | Epalrestat |
| Nā huaʻōlelo like | Epalrest;ONO-2235;Eabeth;Kinedak;Sobistat;(5Z)-5-[(2E)-2-Methyl-3-phenyl-2-propen-1-ylidene]-4-oxo-2-thioxo-3-Thiazolidineacetic Acid;2-[(5Z)-5-[(E)-3-Phenyl-2-methylprop-2-enylidene]- 4-oxo-2-thioxo-3-thiazolidinyl]acetic Acid;(E,E)-2-[5-(2-Methyl-3-phenyl-prop-2-enylidene)-4-oxo-2-sulfanylidene-thiazolidin-3-yl]acetic Acid |
| Kūlana Kūʻai | Ma ka waihona, hana nui |
| Helu CAS | 82159-09-9 |
| ʻĀpana Molekala | C15H13NO3S2 |
| Kaumaha Molecular | 319.39 g/mol |
| Lae hehee | 222.0 a 226.0 ℃ |
| ʻO ka mānoanoa | 1.43±0.10 g/cm3 |
| Ka hikiwawe | DMSO 2 mg/mL Wai <1 mg/mL Ethanol <1 mg/mL |
| Waihona Temp. | Wahi anuanu a maloo (-20 ℃) |
| COA & MSDS | Loaʻa |
| Māhele | API |
| Brand | Kemika Ruifu |
| Nā mea | Nā Kūlana Nānā | Nā hualoaʻa |
| Ka nana aku | ʻAlani a ʻAlani ʻulaʻula Crystalline pauda | Hoʻokō |
| ʻIkepili | E like me ka manawa paʻa o ka HPLC maʻamau | Holo |
| Lae hehee | 222.0 a 226.0 ℃ | 222.4~224.3 ℃ |
| Nalo ma ka maloo | <0.50% | 0.04% |
| Koena ma ka Ignition | <0.20% | 0.03% |
| Nā Metala Kaumaha (Pb) | ≤20ppm | <20ppm |
| Huina paumaele | ≤0.50% | 0.20% |
| Maʻemaʻe / Kaʻina Hanana | >99.5% (HPLC) | 99.8% |
| Infrared Spectrum | Kūlike i ka hoʻolālā | Hoʻokō |
| Ka hopena | Ua hoʻāʻo ʻia ka huahana a hoʻokō i nā kikoʻī i hāʻawi ʻia | |
Pūʻolo:ʻO ka ʻōmole, ʻeke ʻeke alumini, 25kg / pahu pahu pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E kūʻai i loko o nā pahu i hoʻopaʻa ʻia ma kahi hale kūʻai maloʻo a maloʻo (-20 ℃) mai nā mea like ʻole.E pale i ka malamalama a me ka wai.
Hoʻouna:Hāʻawi i ka honua ma FedEx / DHL Express.Hāʻawi wikiwiki a hilinaʻi hoʻi.
Pehea e kūʻai ai?E ʻoluʻolu e kelepona maiDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
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Nā pono?ʻO ke kūlana kiʻekiʻe, ke kumukūʻai kūpono, nā lawelawe ʻoihana a me ke kākoʻo ʻenehana, ka lawe wikiwiki ʻana.
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Nā laʻana?Hāʻawi ka hapa nui o nā huahana i nā laʻana manuahi no ka loiloi maikaʻi, pono e uku ʻia ke kumukūʻai e nā mea kūʻai aku.
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MOQ?ʻAʻohe MOQ.ʻAe ʻia ke kauoha liʻiliʻi.
Manawa Hoʻouna? Inā i loko o ka waihona, ʻekolu lā hoʻouna ʻia.
Kaʻahele?Ma ka Express (FedEx, DHL), ma ka Air, ma ke Kai.
Nā palapala?Ma hope o ka lawelawe kūʻai: COA, MOA, ROS, MSDS, etc.
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Kūkākūkā uku?E hoʻouna mua ʻia ka invoice Proforma ma hope o ka hōʻoia ʻana o ke kauoha, hoʻopili ʻia kā mākou ʻike panakō.Uku e T/T (Telex Transfer), PayPal, Western Union, etc.
UN ID 2811
WGK Kelemānia 3
RTECS XJ5131855
Papa Hazard 6.1
Hui Pūʻulu II
ʻO Epalrestat (CAS: 82159-09-9) ka lua o ka aldose reductase inhibitor e hoʻolauna ʻia ma ka honua a ʻo ka mea mua e hoʻokuʻu ʻia ma Iapana.Hōʻike ʻia ʻo Epalrestat no ka mālama ʻana i ka neuropathy diabetic.Ke noiʻi ʻia nei no ka retinopathy diabetes a me ka nephropathy.ʻO ka Epalrestat kahi mea hoʻopiʻi aldose reductase me IC50 o 72 nM.
Kāohi ʻo Epalrestat i ka Aldose Reductase (AR) i komo i ka pae palena palena i ka hoʻololi ʻana o ka glucose i sorbitol ma lalo o nā kūlana hyperglycemic.ʻO Aldose reductase ka pahuhopu o nā noiʻi lapaʻau he nui e mālama i ka neuropathy diabetic a me ka retinopathy.ʻO Epalrestat kahi lāʻau lapaʻau i ʻae ʻia ma Iapana a me India, i hoʻohana ʻia no ka mālama ʻana i ka neuropathy diabetic.
Hoʻohana ʻia ʻo Epalrestat e pale, hoʻomaikaʻi, a mālama i ka neuropathy peripheral (numbness, pain), vibrational paresthesia, a me ka maʻi maʻi maʻi e pili ana i ka maʻi diabetes.
ʻO ka Epalrestat ma ke ʻano he lāʻau lapaʻau e hōʻemi ana i ka hōʻiliʻili intracellular o ka fructose a me ka sorbitol ma ka hoʻihoʻi ʻana i ka hana aldose reductase, hoʻihoʻi i ka hana Na + -K + -ATPase a me ka inositol, hoʻonui i ka hoʻokumu ʻana o NO i nā cell endothelial, kaohi i ka protein kinase C ala hōʻailona, endothelial cell adhesion, glucose kiʻekiʻe. ʻO ka neutrophil a me ka endothelial adhesion factor expression mediated a hōʻemi i nā huahana carboxymethyl lysine i nā maʻi maʻi maʻi, pēlā e mālama ai i nā maʻi e like me ka maʻi diabetes a me kāna mau pilikia.
