Etravirine TMC-125 CAS 269055-15-4 Assay ≥99.0% (HPLC) API Factory Maʻemaʻe Kiʻekiʻe
Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Etravirine (TMC-125)
CAS: 269055-15-4
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | Etravirine |
Nā huaʻōlelo like | TMC-125 |
Helu CAS | 269055-15-4 |
Helu CAT | RF-API54 |
Kūlana Kūʻai | Ma ka waihona, hoʻonui ʻia a hiki i nā tona |
ʻĀpana Molekala | C20H15BrN6O |
Kaumaha Molecular | 435.28 |
ʻO ka mānoanoa | 1.439 g/cm3 |
Kūlana Hoʻouna | Ma lalo o ka mahana wela |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Pauda Paʻa Keʻokeʻo |
ʻIkepili | Na IR, HPLC |
Lae hehee | 211.0~216.0 ℃ |
Waiwai | ≤0.50% |
Koena ma ka Ignition | ≤0.20% |
Nā Metala Kaumaha | ≤20ppm |
ʻO kēlā me kēia haumia hoʻokahi | ≤0.50% |
Huina paumaele | ≤1.0% |
Hoʻāʻo | ≥99.0% (HPLC) |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Etravirine (TMC-125) (CAS 269055-15-4) ka lua o ka hanauna non-nucleoside reverse transcriptase inhibitor (NNRTI) i hoʻohana ʻia no ka mālama ʻana i ka maʻi HIV.Hōʻike ʻia ia no ka hoʻohana pū ʻana me nā lāʻau antiretroviral ʻē aʻe no ka mālama ʻana i ka maʻi HIV-1 i nā poʻe maʻi makua i ʻike i ka hoʻomaʻamaʻa ʻana i loaʻa nā hōʻike o ka replication viral a me nā maʻi HIV-1 kūʻē i nā NNRTI i loaʻa i kēia manawa a me nā mea antiretroviral ʻē aʻe.ʻO nā NNRTI, me ka nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs), he mau mea koʻikoʻi ia o ka hui pū ʻana i kēia manawa e mālama i ka maʻi HIV-1.Hana nā NRTIs/NtRTI ma ka hoʻokūkū ʻana me nā substrates nucleotide kūlohelohe o ka reverse transcriptase no ka hoʻopili ʻana i loko o ka DNA viral a me ka hoʻopau ʻana i ke kaulahao ma hope.ʻO ka ʻokoʻa, hoʻopaʻa nā NNRTI i kahi pae allosteric o ka enzyme a hoʻopau i ka hana DNA polymerase ma o ka hoʻoulu ʻana i nā loli conformational i ka pūnaewele catalytic.