Ezetimibe Intermediate ZT-5 CAS 189028-95-3 Maʻemaʻe ≥98.0% (HPLC) Hale Hana Kiʻekiʻe
Inoa Kimia | (4S)-3-[(5S)-5-(4-Fluorophenyl)-5-hydroxypentanoyl]-4-phenyl-1,3-oxazolidin-2-one |
Nā huaʻōlelo like | Ezetimibe Kūwaena ZT-5 |
Helu CAS | 189028-95-3 |
Helu CAT | RF-PI146 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C20H20FNO4 |
Kaumaha Molecular | 357.38 |
Brand | ʻO Ruifu Chemical |
'ikamu | Nā kikoʻī |
Ka nana aku | Pada keʻokeʻo a i ʻole keʻokeʻo |
Maʻemaʻe / Kaʻina Hanana | ≥98.0% (HPLC) |
haumia ZT-4 | ≤1.0% |
Enantiomer | ≤0.20% |
Hoʻokahi haumia | ≤1.5% |
Huina paumaele | ≤2.0% |
Kūlana hoʻāʻo | ʻOihana Kūlana |
Hoʻohana | Ezetimibe (CAS: 163222-33-1) Kūwaena |
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o (4S) -3- [(5S) -5- (4-Fluorophenyl) -5-hydroxypentanoyl] -4-phenyl-1,3-oxazolidin-2 -hoʻokahi (CAS: 189028-95-3) me ke kūlana kiʻekiʻe.He mea waena ia o Ezetimibe (CAS: 163222-33-1)
ʻO Ezetimibe (CAS: 163222-33-1) kahi lāʻau ananti-hyperlipidemic i hoʻohana ʻia no ka hoʻohaʻahaʻa ʻana i nā pae cholesterol plasma.Hōʻike ʻia ia ma ke ʻano he lāʻau hoʻohui i ka meaʻai no ka hōʻemi ʻana i ka pae kiʻekiʻe-C, LDL-C, a me ApoB i nā poʻe maʻi e loaʻa ana i ka hypercholesterolemia mua (heterozygous familial a me non-familial).Hoʻohana pū ʻia ia i ka hui pū ʻana me ka HMG-CoA reductase inhibitors. ʻAʻole ʻo Ezetimibe e kāohi i ka synthesis cholesterol i loko o ke ake, a hoʻonui paha i ka excretion bile acid.