Fingolimod Hydrochloride CAS 162359-56-0 Maʻemaʻe ≥99.0% (HPLC) API Hale Hana Maʻemaʻe Kiʻekiʻe
Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Fingolimod Hydrochloride
CAS: 162359-56-0
ʻO Fingolimod Hydrochloride kahi lāʻau lapaʻau FDA i ʻae ʻia no ka mālama ʻana i ka Multiple Sclerosis.
API no ke kūlana kiʻekiʻe, hana kālepa
Inoa Kimia | Fingolimod Hydrochloride |
Nā huaʻōlelo like | Fingolimod HCl;FTY 720 |
Helu CAS | 162359-56-0 |
Helu CAT | RF-API39 |
Kūlana Kūʻai | Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram |
ʻĀpana Molekala | C19H34ClNO2 |
Kaumaha Molecular | 343.93 |
Lae hehee | 102.0~107.0°C |
Brand | Kemika Ruifu |
'ikamu | Nā kikoʻī |
Ka nana aku | Keʻokeʻo a hiki i ka pauda keʻokeʻo |
ʻIkepili | HPLC |
Lae hehee | 102.0~106.0 ℃ |
Ka hikiwawe | Paʻa loa i ka wai |
Maʻemaʻe / Kaʻina Hanana | ≥99.0% (HPLC) |
Māmā (KF) | ≤0.50% |
Koena ma ka Ignition | ≤0.20% |
Nā Metala Kaumaha | ≤20ppm |
Nā mea hoʻoheheʻe koena | |
Dichloromethane | ≤0.05% |
Ethyl Acetate | ≤0.50% |
Ethanol | ≤0.50% |
Methanol | ≤0.30% |
Toluene | ≤0.089% |
THF | ≤0.50% |
DMF | ≤0.088% |
Na mea pili | |
Hoʻokahi haumia | ≤0.50% |
Huina paumaele | ≤1.0% |
Kūlana hoʻāʻo | Kūlana ʻoihana |
Hoʻohana | Mea Hana Lapaʻau Hoʻoikaika (API) |
Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.
Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.
ʻO Shanghai Ruifu Chemical Co., Ltd. ka mea hana nui a me ka mea hoʻolako o Fingolimod Hydrochloride (CAS: 162359-56-0) me ke kūlana kiʻekiʻe.
ʻO Fingolimod Hydrochloride ka lāʻau lapaʻau waha mua no ka mālama ʻana i ka maʻi sclerosis.Ua hoʻomohala maikaʻi ʻia e ka hui lāʻau lapaʻau Novartis, a ua ʻae ʻia no ke kūʻai ʻana e ka US Food and Drug Administration (FDA).ʻO ka maʻi sclerosis he maʻi neurological hoʻonāwaliwali e hiki ke hoʻoneʻe i ka mea maʻi i ke ʻano o ke kaulike, ʻike ʻia nā ʻiʻo spasms a me nā pilikia ʻē aʻe.ʻO Fingolimod Hydrochloride kahi modulator receptor sphingosine-l-phosphate (S1PR).Ma hope o ka phosphorylation, ua hoʻopaʻa ʻia i ka s1P receptor aia ma ka ʻili o ka lymphocyte, ka mea e hoʻololi i ka neʻe ʻana o ka lymphocyte, a hoʻolaha i nā cell i loko o ka ʻiʻo lymphatic, a pale aku i nā lymphocytes mai ka haʻalele ʻana i ka ʻiʻo lymphoid a komo i loko o ka graft.Ma laila, e pale aku ai i kēia mau cell mai ka hoʻokomo ʻana i ke kikowaena o ke kikowaena (CNS), kahi e hoʻokō ai i ka hopena o ka immunosuppression.