Fondaparinux Sodium CAS 114870-03-0 API

ʻO ka wehewehe pōkole:

Inoa Kemika: Fondaparinux Sodium

CAS: 114870-03-0

Ke 'ano: Pada ke'oke'o i ka pauka ke'oke'o

ʻIke: 95.0%~103.0% (ma ke kumu maloʻo)

He Antithrombotic Anticoagulant, he mea pale Xa

Hoʻokaʻaʻike: Kauka Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

Hoʻolako me ka maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Inoa Kemika: Fondaparinux Sodium
CAS: 114870-03-0
He Antithrombotic Anticoagulant, he mea pale Xa
API no ke kūlana kiʻekiʻe, hana kālepa

Na Waiwai Kemika:

Inoa Kimia Fondaparinux Sodium
Helu CAS 114870-03-0
Helu CAT RF-API84
Kūlana Kūʻai Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram
ʻĀpana Molekala C31H43N3O49S8.10Na
Kaumaha Molecular 1728.08
Brand Kemika Ruifu

Nā kikoʻī:

'ikamu Nā kikoʻī
Ka nana aku Keʻokeʻo a hiki i ka pauda keʻokeʻo
Hana ʻIke / ʻIke 95.0%~103.0% (ma ke kumu maloʻo)
Ka hikiwawe Hiki ke hoʻoheheʻe ʻia i ka wai, 2.0M Sodium Chloride a me 0.5M Sodium Hydroxide a hiki ʻole i ka Ethanol.
ʻIkepili 13C-NMR Pono e nānā ʻia nā Resonances no Fondaparinux Sodium ma 58.2, 29.5, 60.5, 60.8, 68.9, 69.2, 69.6, 98.9, 100.4, 101.1, 102.4, 103.9, 176.7 a me 176.7.ʻAʻole ʻokoʻa nā hoʻololi kemika o kēia mau hōʻailona ma mua o ± 0.3ppm nā hōʻailona ʻē aʻe o nā kiʻekiʻe kiʻekiʻe a me nā hoʻololi kemika, pili i ka Fondaparinux Sodium, ʻike ʻia paha ma waena o 58.0~80.5 ppm a me 98.7~104.5ppm
ʻIke HPLC ʻO ka manawa paʻa o ka piko nui o ka hāpana hāpana e pili ana i ka hopena maʻamau
ʻIkepili AAS Pono ka Sodium i ka absorption ma 330.2nm ma lalo o ka hoʻoholo ʻana o ka sodium
pH 6.0~8.0
Sodium (Na) 11.5% ~ 15.0% (I helu ʻia ma ka anhydrous a me nā solvents manuahi)
Sulfate noa ≤0.30%
Ke koena Chloride ≤1.00%
Na mea pili
haumia A ≤0.80%
haumia B ≤0.60%
Hoʻokahi 'ē aʻe haumia ≤0.30%
Huina paumaele ≤2.00%
Nā mea hoʻoheheʻe koena
Methanol ≤3000ppm
Ethanol ≤5000ppm
Ethyl Acetate ≤5000ppm
DMF ≤880ppm
Methylbenzene ≤890ppm
Pyridine ≤50ppm
Waiwai (KF) ≤15.0%
Nā Endotoxins Bacterial ≤3.3EU/mg
Palena Microbial ʻO ka nui o nā Microorganisms ≤100cfu/g
Kūlana hoʻāʻo ʻOihana Kūlana;ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP).
Hoʻohana API, He Antithrombotic Anticoagulant, he Factor Xa Inhibitor

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.

Pono:

1

FAQ:

Noi:

ʻO Fondaparinux Sodium (CAS 114870-03-0) ka mea mua o ka papa hou o ka antithrombotic anticoagulant kemika pili i nā heparins haʻahaʻa molecular weight (LMWH).ʻO Fondaparinux sodium kahi mea Xa inhibitor e hoʻokumu i ka pae hoʻopaʻa kiʻekiʻe no ka anti-coagulant factor antithrombin III (ATIII).ʻO ka paʻa ʻana o ka sodium Fondaparinux ma kēia pūnaewele e hoʻoikaika i ka hopena inhibitory kūlohelohe o ATIII e kūʻē i ka factor Xa ma kahi o 300, e hopena i ka pale ʻana i ka hanauna thrombin.Kūʻai ʻia e GlaxoSmithKline.Ua kūʻai ʻia kahi mana maʻamau i kūkulu ʻia e Alchemia i loko o ka US e Dr. Reddy's Laboratories.Ua hoʻokomo mua ʻia ka sodium Fondaparinux i ka US no ka prophylaxis o ka thrombosis vein hohonu e hiki ke alakaʻi i ka embolism pulmonary ma hope o ke kaʻina orthopedic nui.ʻO kēia molekele synthetic holoʻokoʻa he kope ia o ka heparin pentasaccharide sequence, ʻo ka ʻāpana pōkole loa e hiki ke hoʻokaʻawale i ka antithrombin lllmediated inhibition o ka mea Xa a laila e kāohi ai i ka hana thrombin me ka hana antithrombin.

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