Fulvestrant (ICI 182780) CAS 129453-61-8 API Hale Hana Kiʻi Kiʻekiʻe

ʻO Fulvestrant (ICI 182780) CAS 129453-61-8 API Hale Hana Kūlana Kiʻekiʻe

ʻO ka wehewehe pōkole:

Inoa: Fulvestrant (ICI 182780)

CAS: 129453-61-8

ʻAno: Keʻokeʻo a i ʻole-White Crystalline Powder

ʻIke: 97.0%~102.0% (ma ke kumu maloʻo)

Hoʻohana ʻia ʻo Fulvestrant i ka mālama ʻana i ka maʻi maʻi umauma maʻi hormone-sensitive i nā wahine postmenopausal.

API no ke kūlana kiʻekiʻe, hana kālepa

Inquiry: alvin@ruifuchem.com

E hoʻouna i ka leka uila iā mākou

Huahana Huahana

Nā Huahana Pili

Huahana Huahana

wehewehe:

Hāʻawi Mea Hana me ka Maʻemaʻe kiʻekiʻe a me ka maikaʻi paʻa
Ka inoa: Fulvestrant
CAS: 129453-61-8
Hoʻohana ʻia ʻo Fulvestrant i ka mālama ʻana i ka maʻi maʻi umauma maʻi hormone-sensitive i nā wahine postmenopausal.
API no ke kūlana kiʻekiʻe, hana kālepa

Na Waiwai Kemika:

Inoa Kimia	Fulvestrant
Nā huaʻōlelo like	(7α,17β)-7-[9-[(4,4,5,5,5-Pentafluorpentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3,17-diol;ICI 182780
Helu CAS	129453-61-8
Helu CAT	RF-API81
Kūlana Kūʻai	Ma ka waihona, ʻoi aku ka nui o ka hana a hiki i nā haneli kilogram
ʻĀpana Molekala	C32H47F5O3S
Kaumaha Molecular	606.77
Lae hehee	104.0~106.0 ℃
Ka hikiwawe	Hiki ke hoʻoheheʻe ʻia i ka Methanol, Ethanol;ʻAʻole hiki ke hoʻonā i ka wai
Brand	Kemika Ruifu

Nā kikoʻī:

'ikamu	Nā kikoʻī
Ka nana aku	Keʻokeʻo a i ka pauka kristal keʻokeʻo
ʻIkepili	Na IR, HPLC
Hoʻololi Optical kikoʻī	+108.0° a i +115.0°
Nalo ma ka maloo	≤0.50%
Koena ma ka Ignition	≤0.10%
6-Keto-Fulvestrant	≤0.10%
6,7-Fulvestrant	≤0.10%
ʻO Fulvestrant Sulfone	≤0.20%
Hoʻonui ʻia ʻo Fulvestrant	≤0.30%
ʻO Fulvestrant Sterol Dimmer	≤0.80%
ʻO kēlā me kēia kanaka ka haumia ʻole i hōʻike ʻia	≤0.10%
Huina paumaele	≤1.0%
ʻO Fulvestrant A	42.0%~48.0%
ʻO Fulvestrant B	52.0%~58.0%
DMF	≤620ppm
Nā Metala Kaumaha	≤10ppm
Hoʻāʻo	97.0%~102.0% (ma ke kumu maloʻo)
Waihona	E mālama ʻia i loko o kahi hale kūʻai i paʻa pono i ka mālamalama-kū ʻole i loko o ka friji ma 2 ~ 8 ℃
Kūlana hoʻāʻo	ʻAmelika Hui Pū ʻIa Pharmacopoeia (USP).
Hoʻohana	Estrogen Receptor Antagonist

Pūʻolo a me ka waiho ʻana:

Pūʻolo: ʻO ka ʻōmole, ʻeke ʻeke alumini, pahu pahu pahu, 25kg / pahu, a i ʻole e like me ka makemake o ka mea kūʻai aku.

Kūlana mālama:E mālama i loko o nā pahu i hoʻopaʻa ʻia ma kahi maloʻo a maloʻo;Palekana mai ka malamalama, ka ma'ū a me ka pest infestation.

Pono:

FAQ:

Noi:

ʻO Fulvestrant (ICI-182780) CAS 129453-61-8, he lāʻau hōʻoki ʻiʻo i hoʻomohala ʻia e ka hui ʻo AstraZeneca a hoʻohana ʻia i ka mālama ʻana i ka maʻi maʻi umauma maʻi maʻi hormone-sensitive i nā wahine postmenopausal.ʻO Fulvestrant wale nō ka lāʻau antiestrogen hiki ke hoʻohana nui ʻia ma hope o ka mālama ʻana i ka tamoxifen.ʻO kēia lāʻau lapaʻau he ʻano o ka endocrine therapy, no laila ʻaʻole ia e hoʻoulu i nā hopena ʻino i ʻike pinepine ʻia i ka chemotherapy, e hāʻawi ana i ka hoʻokō hoʻomanawanui maikaʻi.Ua ʻike ʻia nā hoʻokolohua lapaʻau he nui i ka 250mg Fulvestrant ka maikaʻi a me ka palekana mau ma ke ʻano he laina ʻelua o ka mālama ʻana no ka maʻi maʻi umauma kiʻekiʻe.ʻO Fulvestrant kahi mea hoʻohālikelike Estrogen Receptor (ER) Antagonist me IC50 o 0.94 nM i kahi hoʻāʻo ʻole kelepona.Hoʻokomo pū ʻo Fulvestrant i ka autophagy a me ka apoptosis a he hana antitumor.