Ganciclovir CAS 82410-32-0 API BW 759 GCV Antiviral CMV Kāohi Kūlana Kiʻekiʻe

ʻO Ganciclovir (CAS 82410-32-0) aia i nā lāʻau antiviral nucleoside, ʻo ia ke ʻano o ka guanosine derivatives.ʻO Ganciclovir kahi lāʻau antiviral hoʻoikaika makua i hōʻike ʻia no nā maʻi cytomegalovirus (CMV) weliweli i ke ola i nā maʻi immunocompromised.Loaʻa iā ia nā hopena ākea ākea, kiʻekiʻe-efficient i ka maʻi herpes a ʻo ia ka lāʻau koho mua no ka mālama ʻana i ka maʻi cytomegalovirus me ka hopena ikaika i ka maʻi hepatitis B a me ka adenovirus pū kekahi.He homologue ia o ka acyclovir (ACV) me kona hopena antiviral e like me, aka, oi aku ka ikaika ma mua o ka aciclovir, me ka ikaika loa o ka hopena i ka cytomegalovirus pili me ka ma'i AIDS.Hoʻohana ʻia ia no ka mālama ʻana i ka pae induction a me ka manawa mālama i nā maʻi immunocompromised (me nā maʻi AIDS) me ka cytomegalovirus retinitis.Hiki ke hoʻohana ʻia no ka pale ʻana i ka maʻi cytomegalovirus no nā maʻi e loaʻa ana i ka hoʻololi ʻana o ke kino a i ʻole nā ​​​​mea maʻi AIDS me nā hopena maikaʻi i ka hoʻāʻo serology cytomegalovirus.

ʻO Ganciclovir (CAS 82410-32-0) he mea hoʻopiʻi maikaʻi loa, haʻahaʻa haʻahaʻa a me ke koho kiʻekiʻe i hoʻomohala ʻia e ka Syntex Company (United States).ʻO ia ka lāʻau lapaʻau mua i ʻae ʻia e ka US FDA no ka mālama ʻana i ka maʻi cytomegalovirus (CMV).Ua hāʻawi ʻia ʻo Syntex i ke kuleana kūʻokoʻa o ka hana.I Iune 1988, ua ʻae ʻia kēia papa no ka manawa mua e hoʻopaʻa inoa ʻia ma UK, a ukali ʻia e Farani, ʻAmelika Hui Pū ʻIa, Iapana, a me West Germany, Italia a me Kanada a me nā ʻāina ʻē aʻe.A hiki i ka hopena o Iune 1999, ua ʻae ʻia ia ma mua o 70 mau ʻāina a me nā ʻāina no ka pale ʻana i nā maʻi immunodeficiency a me ka maʻi cytomegalovirus o nā maʻi o ka transplantation organ.I ka makahiki 2002, ua loaʻa i nā papa Ganciclovir ka ʻae ʻia e ka FDA, e loaʻa ana i kēia manawa.